A61K6/20

Phosphate crosslinked starch nanoparticle and dental treatments

A phosphorous compound such as STMP is used as a cross-linking agent while making a starch nanoparticle in an emulsion process. Negative charge of the nanoparticle is reduced or reversed by adding cations and/or cationizing the starch optionally while forming the nanoparticles. Anionic active agents, such as fluoride or fluorescein, are optionally incorporated into the nanoparticle during the formation process. For example, a fluoride salt can also be used, which promotes the crosslinking reaction while also providing fluoride in the nanoparticle. The retention of both calcium and fluoride in the nanoparticle is improved when both salts are used. Alternatively, the nanoparticle may be used without added calcium and/or fluoride. The nanoparticles may be useful for tooth remineralization, the treatment of dentinal hypersensitivity, to treat caries, or as a diagnostic agent to locate carious lesions.

Objects made of bulk-solidifying amorphous alloys and method of making same

Metallic dental prostheses made of bulk-solidifying amorphous alloys wherein the dental prosthesis has an elastic strain limit of around 1.2% or more and methods of making such metallic dental prostheses are provided.

Objects made of bulk-solidifying amorphous alloys and method of making same

Metallic dental prostheses made of bulk-solidifying amorphous alloys wherein the dental prosthesis has an elastic strain limit of around 1.2% or more and methods of making such metallic dental prostheses are provided.

COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION
20170280725 · 2017-10-05 ·

Compositions and methods for inhibiting and interrupting biofilm formation, and for destabilizing established biofilms are provided, the novel compositions including polymeric resins and monomeric non-polymerizable and polymerizable resins. More particularly, the compositions and methods enable the protection and removal of biofilms from surfaces in the context of medical, consumer, domestic, food service, environmental and industrial applications, where the effects constitute beneficial and desirable biofilm attenuating activity.

ORAL BIOFILM INHIBITOR

There is provided an oral biofilm inhibitor having an exceptional inhibitory effect on oral biofilm formation. It is an oral biofilm inhibitor comprising a curable composition containing an antimicrobial agent, wherein a compressive strength of a cured product formed by curing the composition is 150 MPa or less, and a content of the antimicrobial agent is 0.001 to 3% by weight. An oral biofilm inhibitor thus obtained is used for inhibiting biofilm formation in an oral cavity by applying a curable composition containing an antimicrobial agent to a dental defect site for allowing the composition to cure at the dental defect site, and then disintegrating the cured composition.

Shade-coordinated, veneering porcelain system for dental prostheses

The invention is related to a shaded porcelain system that contains two types of veneering porcelains: natural enamel/dentin body and opal enamel, as well as stain & glaze porcelain, with CTE that are compatible to and which can be used for veneering a dental prosthesis made of 1) lithium disilicate-based glass-ceramic substructure that is formed by hot pressing or CAD/CAM machined process or 2) YTZP zirconia-based ceramic substructure that is formed by CAD/CAM machined process in order to improve overall esthetics of final prosthesis.

Shade-coordinated, veneering porcelain system for dental prostheses

The invention is related to a shaded porcelain system that contains two types of veneering porcelains: natural enamel/dentin body and opal enamel, as well as stain & glaze porcelain, with CTE that are compatible to and which can be used for veneering a dental prosthesis made of 1) lithium disilicate-based glass-ceramic substructure that is formed by hot pressing or CAD/CAM machined process or 2) YTZP zirconia-based ceramic substructure that is formed by CAD/CAM machined process in order to improve overall esthetics of final prosthesis.

TOOTH MINERALIZATION SOLUTION AND MINERALIZATION METHOD THEREOF
20220031575 · 2022-02-03 ·

Disclosure is a tooth mineralization solution and a mineralization method thereof. The tooth mineralization solution can be used to mineralize collagen and teeth. The mineralization solution component of the present application comprises two parts, namely, reagent A containing non-collagenous protein analogue and calcium salt, and reagent B is phosphate solution. The mineralization method of the tooth mineralization solution of the present application comprises the steps of first applying the reagent A to the surface of tooth, and then applying the reagent B to achieve tooth mineralization. In addition, the mineralization solution of the present application can also be used to achieve biomimetic mineralization of collagen by the same method, comprising the steps of soaking or floating single-layer reconstituted collagen fibril, collagen gel or collagen sponge in the reagent A, and then soaking or floating in the reagent B to achieve biomimetic mineralization.

TOOTH MINERALIZATION SOLUTION AND MINERALIZATION METHOD THEREOF
20220031575 · 2022-02-03 ·

Disclosure is a tooth mineralization solution and a mineralization method thereof. The tooth mineralization solution can be used to mineralize collagen and teeth. The mineralization solution component of the present application comprises two parts, namely, reagent A containing non-collagenous protein analogue and calcium salt, and reagent B is phosphate solution. The mineralization method of the tooth mineralization solution of the present application comprises the steps of first applying the reagent A to the surface of tooth, and then applying the reagent B to achieve tooth mineralization. In addition, the mineralization solution of the present application can also be used to achieve biomimetic mineralization of collagen by the same method, comprising the steps of soaking or floating single-layer reconstituted collagen fibril, collagen gel or collagen sponge in the reagent A, and then soaking or floating in the reagent B to achieve biomimetic mineralization.

LIGHT-CURING DENTAL COMPOSITES WITH INCREASING OPACITY
20170224591 · 2017-08-10 · ·

Radically polymerizable dental material which contains (a) at least one polyfunctional radically polymerizable monomer, (b) at least one further radically polymerizable monomer which can be monofunctional or polyfunctional, (c) at least one photoinitiator for the radical polymerization and (d) at least one filler. The material is characterized in that the mixture of the monomers (a) and (b) has a refractive index of from 1.50 to 1.70 and in that the refractive index of the monomer mixture before the curing corresponds to the refractive index of the filler used or is higher by up to 0.013 and after the curing is higher than the refractive index of the filler by at least 0.02.