An orthodontic adhesive includes components capable of allowing easy debonding of an orthodontic device from a patient's tooth. The adhesive includes an engineered marine mussel protein. The adhesive may include at least one photocleavable moiety. The adhesive is applied in one or more individual layers. One of the components of the adhesive is capable of binding to a tooth and the other component may be capable of binding to an orthodontic device. A method of adhering an orthodontic device to a tooth includes applying a layer of an orthodontic adhesive to either the tooth or the orthodontic device or the tooth and the orthodontic device and affixing the orthodontic device to the tooth with the orthodontic adhesive situated between the tooth and the orthodontic device. The engineered marine mussel protein includes one or more catechol moieties or one or more derivatives of a catechol moiety.

An orthodontic adhesive includes components capable of allowing easy debonding of an orthodontic device from a patient's tooth. The adhesive includes an engineered marine mussel protein. The adhesive may include at least one photocleavable moiety. The adhesive is applied in one or more individual layers. One of the components of the adhesive is capable of binding to a tooth and the other component may be capable of binding to an orthodontic device. A method of adhering an orthodontic device to a tooth includes applying a layer of an orthodontic adhesive to either the tooth or the orthodontic device or the tooth and the orthodontic device and affixing the orthodontic device to the tooth with the orthodontic adhesive situated between the tooth and the orthodontic device. The engineered marine mussel protein includes one or more catechol moieties or one or more derivatives of a catechol moiety.

A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time.

A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time.

The present invention relates in a first aspect to an adhesion material for use in an individual containing encapsulated phase-change material. In particular, the adhesion material is for cosmetical or medicinal use in the body of an individual. The adhesion material contains encapsulated phase-change material having preferably a phase transition temperature above 40° C., like above 55° C. The adhesion material is particularly useful for adhering elements, like dental restorations, e.g. crowns or bridge, or brackets on elements in the body of an individual, like teeth or implants. That is, the adhesion material is particularly useful for adhering material in dental applications. In another aspect, a method is provided allowing removing a bracket, a crown or bridge, from implants, abutments or teeth. Furthermore, dental implant restoration systems and kits for permanent fixation of implants allowing improved removal thereof are provided.

The present invention relates in a first aspect to an adhesion material for use in an individual containing encapsulated phase-change material. In particular, the adhesion material is for cosmetical or medicinal use in the body of an individual. The adhesion material contains encapsulated phase-change material having preferably a phase transition temperature above 40° C., like above 55° C. The adhesion material is particularly useful for adhering elements, like dental restorations, e.g. crowns or bridge, or brackets on elements in the body of an individual, like teeth or implants. That is, the adhesion material is particularly useful for adhering material in dental applications. In another aspect, a method is provided allowing removing a bracket, a crown or bridge, from implants, abutments or teeth. Furthermore, dental implant restoration systems and kits for permanent fixation of implants allowing improved removal thereof are provided.

The present invention provides a dental adhesive kit including a bonding material that has a good state stability, that has a good balance between photocurability for LED light irradiation and stability to ambient light, and that is capable of exhibiting high bond strengths to both enamel and dentin with small variability even when subjected to photocuring with a high-power LED irradiation device. The present invention relates to a dental adhesive kit including a primer and a bonding material. The primer includes an acid group-containing monomer, a hydrophilic monomer, and water, and the bonding material includes a hydrophilic monomer (B-1), an aromatic bifunctional monomer (B-2), an aliphatic bifunctional monomer (B-3), α-diketone (B-4), (bis)acylphosphine oxide (B-5), and a benzotriazole compound (B-6) as defined in the description. The content of (B-4) is 0.6 to 2 parts by weight per part by weight of (B-5), and the content of (B-6) is 0.01 to 3 parts by weight per 100 parts by weight of (B-3).

The present invention provides a dental adhesive kit including a bonding material that has a good state stability, that has a good balance between photocurability for LED light irradiation and stability to ambient light, and that is capable of exhibiting high bond strengths to both enamel and dentin with small variability even when subjected to photocuring with a high-power LED irradiation device. The present invention relates to a dental adhesive kit including a primer and a bonding material. The primer includes an acid group-containing monomer, a hydrophilic monomer, and water, and the bonding material includes a hydrophilic monomer (B-1), an aromatic bifunctional monomer (B-2), an aliphatic bifunctional monomer (B-3), α-diketone (B-4), (bis)acylphosphine oxide (B-5), and a benzotriazole compound (B-6) as defined in the description. The content of (B-4) is 0.6 to 2 parts by weight per part by weight of (B-5), and the content of (B-6) is 0.01 to 3 parts by weight per 100 parts by weight of (B-3).

The present invention provides a dental polymerizable composition that requires less discharging force, is easily formable, has low polymerization shrinkage stress during curing, and exhibits high stain resistance and surface gloss when cured. The present invention relates to a dental polymerizable composition including a (meth)acrylic block copolymer (A), a polymerizable monomer (B), and a polymerization initiator (C). The (meth)acrylic block copolymer (A) consists of a (meth)acrylic polymer block (a) having a curable functional group and a (meth)acrylic polymer block (b) having no curable functional group. The curable functional group has a partial structure represented by the following general formula (1):

##STR00001##

β-Ketophosphonic acid according to general formula I: ##STR00001##
in which A=an aliphatic C.sub.1-C.sub.18 radical which can be interrupted by —O—, —S—, —CO—O— or —O—CO—C—; n=1, 2, 3 or 4; m=1 or 2; X=absent or a C.sub.1-C.sub.10 radical which can be interrupted by —O—, —S—, —CO—C—, —O—CO—NH— or —CO—NR.sup.1—, wherein R.sup.1 is H or C.sub.1-C.sub.7-alkyl; and PG=a group which can undergo free radical polymerization. The β-ketophosphonic acids are suitable in particular for the preparation of dental materials.