A method for making a ceramic body comprised of a ceramic material having an inhibitory effect on bacterial growth is provided. A dental prosthesis may be made of a ceramic material that comprises a molybdenum-containing component on a portion of the prosthesis that contacts the gingival surface of a patient. In one method, a porous zirconia ceramic structure is shaped in the form of a dental prosthesis, and then infiltrated with a molybdenum-containing composition, before sintering to densify the ceramic structure.

What is described is a dental light-curable composition for elective production of a visible restoration in the anterior region or for filling of a cavity in the posterior region, comprising a total amount (A) of free-radically polymerizable monomers, where this total amount (A) consists of one, two, three or more than three free-radically polymerizable monomers and has a refractive index n.sub.A, 470nm in the range from 1.470 to 1.560, a total amount (B1) of nonaggregated and nonagglomerated inorganic filler particles having a particle size in the range from 7 to 70 nm, where this total amount (B1) has a refractive index n.sub.B1, 470nm in the range from 1.460 to 1.570 and where this total amount (B1) is in the range from 10 to 30 percent by volume, based on the overall dental light-curable composition, a total amount (B2) of inorganic filler particles having a particle size in the range from 0.12 μm to 10 μm, where this total amount (B2) has a refractive index n.sub.B2,470nm in the range from 1.450 to 1.560, and a total amount (C) of photoinitiators.

A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time.

A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time.

A phosphorous compound such as STMP is used as a cross-linking agent while making a starch nanoparticle in an emulsion process. Negative charge of the nanoparticle is reduced or reversed by adding cations and/or cationizing the starch optionally while forming the nanoparticles. Anionic active agents, such as fluoride or fluorescein, are optionally incorporated into the nanoparticle during the formation process. For example, a fluoride salt can also be used, which promotes the crosslinking reaction while also providing fluoride in the nanoparticle. The retention of both calcium and fluoride in the nanoparticle is improved when both salts are used. Alternatively, the nanoparticle may be used without added calcium and/or fluoride. The nanoparticles may be useful for tooth remineralization, the treatment of dentinal hypersensitivity, to treat caries, or as a diagnostic agent to locate carious lesions.

This invention relates to compositions and medical devices comprising anti-microbial active particles, for inhibiting microbial growth. This invention further provides methods of making such compositions and medical devices.

This invention relates to compositions and medical devices comprising anti-microbial active particles, for inhibiting microbial growth. This invention further provides methods of making such compositions and medical devices.

Lithium silicate glass ceramics and glasses containing specific oxides of divalent elements are described which crystallize at low temperatures and are suitable in particular as dental materials.

There is provided an oral biofilm inhibitor having an exceptional inhibitory effect on oral biofilm formation. It is an oral biofilm inhibitor comprising a curable composition containing an antimicrobial agent, wherein a compressive strength of a cured product formed by curing the composition is 150 MPa or less, and a content of the antimicrobial agent is 0.001 to 3% by weight. An oral biofilm inhibitor thus obtained is used for inhibiting biofilm formation in an oral cavity by applying a curable composition containing an antimicrobial agent to a dental defect site for allowing the composition to cure at the dental defect site, and then disintegrating the cured composition.

A family of cobalt based dental alloys suitable for PFM and SLM applications that do not exhibit ferromagnetism and that are capable of meeting the ADA requirements for a “noble” alloy are provided. The dental alloys comprise at least 25 wt. % of noble metals selected from either platinum alone or a combination of platinum and ruthenium, and from 23 to 32 wt. % chromium. Additional additive materials may be included in concentrations up to 3 wt. %. The ruthenium optionally comprises up to 8 wt. %, and in some embodiments from at least 5 wt. % to 8 wt. % of the noble metals such that the dental alloys are capable of meeting the ADA requirements for a “noble” alloy.