A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time.

A pre-mixed strontium silicate-based biological hydraulic cement paste composition and preparation method and use thereof are disclosed. The pre-mixed strontium silicate-based biological hydraulic cement paste of the disclosure uses strontium silicate as the main phase and at least one non-aqueous solvent that is miscible with water, and preferably, it may further include at least one calcium phosphate compound and at least one radiopaque material, to prepare a biological hydraulic cement paste with excellent injectability. The material remains as a fluid under a sealed condition, and hydrates, solidifies and hardens when it is placed in a physiological environment and contacts with a physiological body fluid. The strontium silicate-based material having excellent biocompatibility and biological activity is used to prepare a pre-mixed strontium silicate-based cement paste, which can be used for medical and dental applications including fields of pulp capping, root canal therapy, dental restorations and the like.

A composite material including silanated filler and mixed polymerizable monomer, having a stable pasty property which keeps well and has a consistent usability. A composite material containing a silanated filler, a polymerizable monomer, and a polymerization initiator, and may be produced by a process which includes a mixed polymerizable monomer preparing step, a silanation step, a silanated filler preserving step, a composite material preparing step, a composite material preserving step, a composite material filling step, and a small quantity preserving container preserving step.

A composite material including silanated filler and mixed polymerizable monomer, having a stable pasty property which keeps well and has a consistent usability. A composite material containing a silanated filler, a polymerizable monomer, and a polymerization initiator, and may be produced by a process which includes a mixed polymerizable monomer preparing step, a silanation step, a silanated filler preserving step, a composite material preparing step, a composite material preserving step, a composite material filling step, and a small quantity preserving container preserving step.

A curable mixture and method of using the mixture are disclosed. In some embodiments, the mixture comprises an alginate polymer, and comprises properties suitable for use as a tooth filling after curing.

Dental compositions and methods of formulating a dental composition are described. In one embodiment, the dental composition comprises a polymerizable resin comprising one or more ethylenically unsaturated monomers or oligomers and nanoparticles. The nanoparticles have a refractive index of at least 1.600 and an average discrete or aggregate particle size of no greater than 100 nm. The dental composition further comprises inorganic metal oxide filler having a discrete or aggregate average particle size of at least 200 nm. The nanoparticles are present at a concentration to provide a refractive index differential between the cured polymerizable resin and inorganic metal oxide filler such that the contrast ratio of the dental composition is at least 40.

A dental liner and a manufacturing method therefor are disclosed. The dental liner is a dental liner for coupling feldspar porcelain and zirconia and includes: silicon dioxide; aluminum oxide; 1,4-butanediol for maintaining the moisture of the dental liner and preventing the generation of layers; and a zirconia powder for coupling the dental liner and zirconia by strengthening chemical bonding of the dental liner and zirconia.

The present invention relates to a kit of parts comprising Part A and Part B, Part A comprising: ascorbic acid, component(s) comprising an ascorbic acid moiety or derivative(s) thereof, optionally polymerizable component(s) without acidic moieties, optionally polymerizable component(s) with acidic moieties, and optionally filler(s), Part B comprising polymerizable component(s) without acidic moieties, polymerizable component(s) with acidic moieties, transition metal component(s), organic peroxide(s), and optionally filler(s), The invention is also directed to a redox initiator system comprising ascorbic acid, component(s) comprising an ascorbic acid moiety or derivative(s) thereof, transition metal component(s), preferably comprising a copper or iron ion containing salt, organic peroxide(s), preferably comprising a hydroperoxide or di-peroxide. The kit of parts and redox initiator system are particularly useful in the dental field.

The present invention relates to a kit of parts comprising Part A and Part B, Part A comprising: ascorbic acid, component(s) comprising an ascorbic acid moiety or derivative(s) thereof, optionally polymerizable component(s) without acidic moieties, optionally polymerizable component(s) with acidic moieties, and optionally filler(s), Part B comprising polymerizable component(s) without acidic moieties, polymerizable component(s) with acidic moieties, transition metal component(s), organic peroxide(s), and optionally filler(s), The invention is also directed to a redox initiator system comprising ascorbic acid, component(s) comprising an ascorbic acid moiety or derivative(s) thereof, transition metal component(s), preferably comprising a copper or iron ion containing salt, organic peroxide(s), preferably comprising a hydroperoxide or di-peroxide. The kit of parts and redox initiator system are particularly useful in the dental field.

A dental composite or coating that comprises at least one photopolymerizable resin, at least one inorganic filler, a photoinitator, and at lease one interference platelet. The dental composite is able to adapt and match the color and shade of adjacent tooth structure in the cavity in which it is placed, without the need for conventional dyes and pigments, although it may be desirable to use dyes and pigments in a specific shade series.