The present invention relates to the use of cannabidiol (CBD) for the treatment of seizures associated with rare epilepsy syndromes. In particular the seizures associated with rare epilepsy syndromes that are treated are those which are experienced inpatients with mutation in the potassium channel (KCN) gene. In a further embodiment the types of seizures include tonic, tonic-clonic, absence and focal seizures with impairment. Preferably the dose of CBD is between 5 mg/kg/day to 50 mg/kg/day.

The present disclosure provides a cannabinoid composition comprising combinations of at least two THC homologues, wherein the first THC homologue is THCB and the second THC homologue is THCP.

Compositions containing mono- and di-glycerides with at least 20% (w/w) omega-3 fatty acyl groups and methods of utilizing same.

The present technology provides composition that includes pectin and a rare sugar, polydextrose, or a combination thereof; wherein the composition is a gummy and essentially free of gelatin. The composition has less than about 50 wt % sugar, a glycemic index of about 50 or less, about 10 calories or less, or a combination of two or more thereof. The gummy can be used to treat a patient such a patient with a nutritional deficiency or preventing a nutritional deficiency.

Compositions and methods for prophylactically sustaining and/or maintaining a robust endocannabinoid system in patients for modulating excess inflammatory response and inflammatory diseases over the mammalian lifespan to mitigate age-related discomfort. Specifically, a method of uniquely treating inflammatory and neuropathic pain in a mammal by administering a synergistic pharmaceutical daily dosage form comprising: palmitoylethanolamide (PEA), beta-caryophyllene (BCP) and docosahexaenoic acid (DHA).

The present invention relates to the use of cannabidiol (CBD) for the treatment of seizures associated with rare epilepsy syndromes. In particular the seizures associated with rare epilepsy syndromes that are treated are those which are experienced in patients with PURA gene mutation. In a further embodiment the types of seizures include tonic, atonic and focal seizures with secondary generalisation. Preferably the dose of CBD is between 5 mg/kg/day to 50 mg/kg/day.

The present invention relates to the use of cannabidiol (CBD) for the treatment of seizures associated with rare epilepsy syndromes related to brain injury. In particular the seizures associated with rare epilepsy syndromes that are treated are those which are experienced in patients diagnosed with hypoxic ischaemic encephalopathy (HIE) or anoxia at birth. In a further embodiment the types of seizures include tonic, tonic-clonic, atonic, myoclonic, absence, focal seizures with impairment and spasms. Preferably the dose of CBD is between 5 mg/kg/day to 50 mg/kg/day.

The present invention relates to a formulation comprising a nano lipid carrier system comprising an active ingredient, low phase transition solid lipid, PEGylated lipid, surfactants and cosolvents etc, dispersed in water or aqueous medium. The hydrodynamic diameter of the nanocarrier system in aqueous media is less than about 1000 nm. The present invention formulation can be in the form of a liquid (solution, suspension, dispersion), liquid filled hard gelatin capsule, soft gelatin capsule or a liquid concentrate.

The invention relates to a simple, cost-effective and eco-friendly process of recovering one or more cannabinoids from complex natural products, especially cannabidiol (CBD) and/or cannabidiolic acid (CBDA) from raw Cannabis plant material or extracts thereof.

There is disclosed a composition for topical application of a cannabinoid as active ingredient comprising a solution of the cannabinoid in an excipient formulation comprising a polyhydric alcohol as partition coefficient enhancer, a saturated long-chain fatty acid or alcohol thereof as diffusion coefficient enhancer, and a co-solvent, wherein the saturated long-chain fatty acid or alcohol has a carbon chain length of from C10 to C16. The composition can be used in the treatment of a variety of conditions.