Patent classifications
A61K33/24
Palladium Hyaluronic Acid Particles and Methods of Managing Cancer or Angiogenic Conditions
This disclosure relates to palladium hyaluronic acid particles such as dibenzylideneacetone palladium hyaluronic acid particles. In certain embodiments, this disclosure relates to methods of managing cancer or angiogenic conditions using particles disclosed herein and pharmaceutical compositions comprising the same. In certain embodiments, an objective of this disclosure is hyaluronic acid targeting of CD44, a tumor stem cell marker. In certain embodiments, this disclosure relates to treatment with hyaluronic acid palladium particles disclosed herein for depleting CD44 cells.
Palladium Hyaluronic Acid Particles and Methods of Managing Cancer or Angiogenic Conditions
This disclosure relates to palladium hyaluronic acid particles such as dibenzylideneacetone palladium hyaluronic acid particles. In certain embodiments, this disclosure relates to methods of managing cancer or angiogenic conditions using particles disclosed herein and pharmaceutical compositions comprising the same. In certain embodiments, an objective of this disclosure is hyaluronic acid targeting of CD44, a tumor stem cell marker. In certain embodiments, this disclosure relates to treatment with hyaluronic acid palladium particles disclosed herein for depleting CD44 cells.
Palladium Hyaluronic Acid Particles and Methods of Managing Cancer or Angiogenic Conditions
This disclosure relates to palladium hyaluronic acid particles such as dibenzylideneacetone palladium hyaluronic acid particles. In certain embodiments, this disclosure relates to methods of managing cancer or angiogenic conditions using particles disclosed herein and pharmaceutical compositions comprising the same. In certain embodiments, an objective of this disclosure is hyaluronic acid targeting of CD44, a tumor stem cell marker. In certain embodiments, this disclosure relates to treatment with hyaluronic acid palladium particles disclosed herein for depleting CD44 cells.
COMPOSITIONS AND METHODS COMPRISING ENERGY ABSORBING MATERIALS FOR FOLLICULAR DELIVERY
The present invention provides compositions comprising energy (e.g., light) absorbing submicron particles (e.g., nanoparticles comprising a silica core and a gold shell) and methods for delivering such particles via topical application. This delivery is facilitated by application of mechanical agitation (e.g. massage), acoustic vibration in the range of 10 Hz-20 kHz, ultrasound, alternating suction and pressure, and microjets.
COMPOSITIONS AND METHODS COMPRISING ENERGY ABSORBING MATERIALS FOR FOLLICULAR DELIVERY
The present invention provides compositions comprising energy (e.g., light) absorbing submicron particles (e.g., nanoparticles comprising a silica core and a gold shell) and methods for delivering such particles via topical application. This delivery is facilitated by application of mechanical agitation (e.g. massage), acoustic vibration in the range of 10 Hz-20 kHz, ultrasound, alternating suction and pressure, and microjets.
TERAHERTZ MATERIAL HAVING THERAPEUTIC AND HEALTH CARE EFFECTS, PREPARATION METHOD THEREFOR AND USE THEREOF
The present invention discloses a terahertz material with therapeutic and health care effect and its preparation method and application, which includes the following raw materials in parts by weight: 15˜28 SiO.sub.2, 3˜8 Al.sub.2O.sub.3, 1˜3 selenium, 2˜5 germanium, 10˜15 Fe.sub.2O.sub.3, 35˜45 ochre, 20˜35 zinc oxide, 65˜80 CaCO.sub.3, 0.1˜0.5 rare earth palladium, 1˜10 SiO.sub.x, wherein the raw materials of components are mixed according to the above proportion, and crushing, heating to 600˜1200° C. in an oxygen free environment for 3˜8 hours, and then secondary crushing, having a fineness of 3000˜8000 mesh; and then, after crushing again and powdering processing, the fineness reaches more than 10000 mesh. After being enhanced treatment by the terahertz irradiation line, the terahertz materials with therapeutic and health care effects are obtained. They can be processed and manufactured into a variety of physiotherapy equipment, with fast action speed and stable effect on human body.
TERAHERTZ MATERIAL HAVING THERAPEUTIC AND HEALTH CARE EFFECTS, PREPARATION METHOD THEREFOR AND USE THEREOF
The present invention discloses a terahertz material with therapeutic and health care effect and its preparation method and application, which includes the following raw materials in parts by weight: 15˜28 SiO.sub.2, 3˜8 Al.sub.2O.sub.3, 1˜3 selenium, 2˜5 germanium, 10˜15 Fe.sub.2O.sub.3, 35˜45 ochre, 20˜35 zinc oxide, 65˜80 CaCO.sub.3, 0.1˜0.5 rare earth palladium, 1˜10 SiO.sub.x, wherein the raw materials of components are mixed according to the above proportion, and crushing, heating to 600˜1200° C. in an oxygen free environment for 3˜8 hours, and then secondary crushing, having a fineness of 3000˜8000 mesh; and then, after crushing again and powdering processing, the fineness reaches more than 10000 mesh. After being enhanced treatment by the terahertz irradiation line, the terahertz materials with therapeutic and health care effects are obtained. They can be processed and manufactured into a variety of physiotherapy equipment, with fast action speed and stable effect on human body.
STIMULI - OR BIO- RESPONSIVE COPOLYMERS, THE POLYMERSOMES COMPRISING THE SAME AND THEIR USE IN DRUG DELIVERY
The present invention concerns amphiphilic copolymers that may be photo- or redox-cleavable and that may assemble into polymersomes. It also concerns their process of preparation and their use as ding carriers.
Process for removing mercury ions from bodily fluids using titanium metallate ion exchange compositions
A process for removing Hg.sup.2+ toxins from bodily fluids is disclosed. The process involves contacting the bodily fluid with a titanium metallate ion exchanger to remove the metal toxins in the bodily fluid, including blood and gastrointestinal fluid. Alternatively, blood can be contacted with a dialysis solution which is then contacted with the ion exchanger. The titanium metallate ion exchangers are represented by the following empirical formula:
A.sub.mTiNb.sub.aSi.sub.xO.sub.y. A composition is provided with the combination of the titanium metallate ion exchanger and bodily fluids or dialysis solutions. Also, provided is an apparatus comprising a matrix and the titanium metallate ion exchanger.
LIQUID DRESSING COMPOSITIONS AND THEIR VETERINARY USES
Liquid dressing compositions liquid for veterinary use in the treatment or prevention of infection and/or wounds are described that comprise shellac, an anti-infective metal active and a solvent. The compositions are capable of forming a barrier when topically applied to a non-human animal subject, providing an easily applied barrier for protecting lesions and other wounds from external infective agents in a veterinary setting.