A61K35/02

COMPOSITIONS AND METHODS FOR TREATING SKIN CONDITIONS
20220257646 · 2022-08-18 ·

Provided herein are methods and compositions for the treatment or prevention of a skin disease (e.g., acne) in a subject by administering to the subject a composition comprising iron or cobalt.

NON-LETHAL DEFENSIVE FLUID COMPOSITION AND PRESSURIZED DELIVERY SYSTEM
20220244024 · 2022-08-04 ·

A lubric gel composition for personal defense includes a fatty acid at a concentration ranging from 5 wt % to 10 wt % of the composition, a thickening agent at a concentration ranging from 1.75 wt % to 8.75 wt % of the composition, a detergent at a concentration ranging from 1.03 wt % to 4.07 wt % of the composition, a surfactant at a concentration ranging from 2 wt % to 15 wt % of the composition, and water at a concentration ranging from 66 wt % to 90.21 wt % of the composition.

NON-LETHAL DEFENSIVE FLUID COMPOSITION AND PRESSURIZED DELIVERY SYSTEM
20220244024 · 2022-08-04 ·

A lubric gel composition for personal defense includes a fatty acid at a concentration ranging from 5 wt % to 10 wt % of the composition, a thickening agent at a concentration ranging from 1.75 wt % to 8.75 wt % of the composition, a detergent at a concentration ranging from 1.03 wt % to 4.07 wt % of the composition, a surfactant at a concentration ranging from 2 wt % to 15 wt % of the composition, and water at a concentration ranging from 66 wt % to 90.21 wt % of the composition.

A PHARMACEUTICAL HERBO-MINERAL METALLIC COMPOSITION AND A PROCESS FOR PREPARATION THEREOF

The present disclosure relates to a pharmaceutical herbo-mineral-metallic composition and its process of preparation. The pharmaceutical herbo-mineral-metallic composition comprises Suvarna bhasma, wherein the Suvarna bhasma is obtained by stabilizing Suvarna with fresh juice of the leaves of Ocimum sanctum, Mouktik bhasma, Guduchi sattva, and at least one excipient. The pharmaceutical herbo-mineral-metallic composition of the present disclosure can be used for alleviating disease induced and therapy induced adverse effects. It can also improve quality of life of the patients as assessed by Karnofsky score and wellbeing by QLQ CTC 30 score. The pharmaceutical herbo-mineral-metallic composition of the present disclosure can be beneficial in increasing disease free survival and overall survival in various cancers. It is not toxic in nature when consumed for a long period of time.

A PHARMACEUTICAL HERBO-MINERAL METALLIC COMPOSITION AND A PROCESS FOR PREPARATION THEREOF

The present disclosure relates to a pharmaceutical herbo-mineral-metallic composition and its process of preparation. The pharmaceutical herbo-mineral-metallic composition comprises Suvarna bhasma, wherein the Suvarna bhasma is obtained by stabilizing Suvarna with fresh juice of the leaves of Ocimum sanctum, Mouktik bhasma, Guduchi sattva, and at least one excipient. The pharmaceutical herbo-mineral-metallic composition of the present disclosure can be used for alleviating disease induced and therapy induced adverse effects. It can also improve quality of life of the patients as assessed by Karnofsky score and wellbeing by QLQ CTC 30 score. The pharmaceutical herbo-mineral-metallic composition of the present disclosure can be beneficial in increasing disease free survival and overall survival in various cancers. It is not toxic in nature when consumed for a long period of time.

Homeopathic complex
11298421 · 2022-04-12 ·

The present invention is directed to a homeopathic complex for use in the treatment of various diseases or disorders, including use as an anti-infective agent and/or in the regeneration of diseased or damaged tissue. Ideally, the anti-infective homeopathic complex of the invention may comprise a homeopathic tincture or dilutions thereof of Hepar sulphuris calcareum or other similar profiled Calcarea or Sulphur salt or acid, Lachesis muta or other remedy with a similar profile, Mercurius Solubilis or similar mercury containing remedy and Silica or other silica containing compounds.

Homeopathic complex
11298421 · 2022-04-12 ·

The present invention is directed to a homeopathic complex for use in the treatment of various diseases or disorders, including use as an anti-infective agent and/or in the regeneration of diseased or damaged tissue. Ideally, the anti-infective homeopathic complex of the invention may comprise a homeopathic tincture or dilutions thereof of Hepar sulphuris calcareum or other similar profiled Calcarea or Sulphur salt or acid, Lachesis muta or other remedy with a similar profile, Mercurius Solubilis or similar mercury containing remedy and Silica or other silica containing compounds.

Homeopathic complex
11298421 · 2022-04-12 ·

The present invention is directed to a homeopathic complex for use in the treatment of various diseases or disorders, including use as an anti-infective agent and/or in the regeneration of diseased or damaged tissue. Ideally, the anti-infective homeopathic complex of the invention may comprise a homeopathic tincture or dilutions thereof of Hepar sulphuris calcareum or other similar profiled Calcarea or Sulphur salt or acid, Lachesis muta or other remedy with a similar profile, Mercurius Solubilis or similar mercury containing remedy and Silica or other silica containing compounds.

MONOCLONAL ANTIBODY TARGETING A UNIQUE SIALOGLYCOSYLATED CANCER-ASSOCIATED EPITOPE OF CD43
20220098321 · 2022-03-31 ·

The present invention relates to a monoclonal mouse antibody produced by the hybridoma cell deposited under ICLC accession number ICLC PD n.sup.o 16001. Furthermore, the invention relates to an antibody comprising a heavy chain variable region comprising complementarity determining regions CDRH1, CDRH2 and CDRH3, and a light chain variable region comprising complementarity determining regions CDRL1, CDRL2 and CDRL3, wherein CDRH1, CDRH2, CDRH3, CDRL1, CDRL2, and CDRL3 comprise the amino acid sequences GFTFSSFGMH (SEQ ID NO: 1), YISSGSGNFYYVDTVKG (SEQ ID NO: 43), STYYHGSRGAMDY (SEQ ID NO: 3), SASSSVSSMYWY (SEQ ID NO: 4), DTSKMAS (SEQ ID NO: 5), and QQWSSYPPIT (SEQ ID NO: 6), respectively. In addition, the invention relates to antibodies recognizing the same epitope.

MONOCLONAL ANTIBODY TARGETING A UNIQUE SIALOGLYCOSYLATED CANCER-ASSOCIATED EPITOPE OF CD43
20220098321 · 2022-03-31 ·

The present invention relates to a monoclonal mouse antibody produced by the hybridoma cell deposited under ICLC accession number ICLC PD n.sup.o 16001. Furthermore, the invention relates to an antibody comprising a heavy chain variable region comprising complementarity determining regions CDRH1, CDRH2 and CDRH3, and a light chain variable region comprising complementarity determining regions CDRL1, CDRL2 and CDRL3, wherein CDRH1, CDRH2, CDRH3, CDRL1, CDRL2, and CDRL3 comprise the amino acid sequences GFTFSSFGMH (SEQ ID NO: 1), YISSGSGNFYYVDTVKG (SEQ ID NO: 43), STYYHGSRGAMDY (SEQ ID NO: 3), SASSSVSSMYWY (SEQ ID NO: 4), DTSKMAS (SEQ ID NO: 5), and QQWSSYPPIT (SEQ ID NO: 6), respectively. In addition, the invention relates to antibodies recognizing the same epitope.