A therapeutic composition and a method of producing it by light-activating hypericin in a carrier or solvent. Preferably, the composition is made by combining dried flowers and/or flower stems of St. John's Wort with edible oil and exposing the mixture to the sun for a prolonged time. This process serves to light-activate the hypericin before its use and reduce risk of skin phototoxicity. The composition can be used for treating undesirable conditions such as mouth sores and vaginal infections.

A therapeutic composition and a method of producing it by light-activating hypericin in a carrier or solvent. Preferably, the composition is made by combining dried flowers and/or flower stems of St. John's Wort with edible oil and exposing the mixture to the sun for a prolonged time. This process serves to light-activate the hypericin before its use and reduce risk of skin phototoxicity. The composition can be used for treating undesirable conditions such as mouth sores and vaginal infections.

The present invention relates to compositions comprising one or more probiotic bacterial strains and one or more lipid modifying active ingredients. The compositions can be used in the management of cholesterol and/or hypertension.

A method for the management of cancer and treatment of cancer comorbidities, including but not limited to cancer-related fatigue, cachexia, anorexia, pain, anemia, asthenia, depression, muscle weakness, nausea, vomiting, skin, and skin appendages adverse reactions; the method including the administration by the conventional and non-conventional oral, topical, parenteral routes and intra-tumoral injection, or in combination thereof, or the administration as adjuvant potentiator in other therapies using the forenamed routes, of a composition containing as active ingredient an extract of Allium species, which contains querceting, an extract of Citrus species and an extract of Pauffinia species and an extract of Theobroma species.

A method for the management of cancer and treatment of cancer comorbidities, including but not limited to cancer-related fatigue, cachexia, anorexia, pain, anemia, asthenia, depression, muscle weakness, nausea, vomiting, skin, and skin appendages adverse reactions; the method including the administration by the conventional and non-conventional oral, topical, parenteral routes and intra-tumoral injection, or in combination thereof, or the administration as adjuvant potentiator in other therapies using the forenamed routes, of a composition containing as active ingredient an extract of Allium species, which contains querceting, an extract of Citrus species and an extract of Pauffinia species and an extract of Theobroma species.

A moringa extract containing a benzyl glucosinolate in a content of 6% by mass or more, calculated as a dry solid content of the extract, wherein the extract does not substantially contain an alkaloid. The moringa extract of the present invention for solving a first aspect is useful in the field of foodstuff or the like. Also, the PPAR activator of the present invention for solving a second aspect has excellent PPAR activation action, and has no disadvantages in side effects, so that it can be ingested for long term, which can be preferably used in foodstuff and the like. Therefore, the PPAR activator of the present invention for solving a second aspect can be expected to be used as a food, a supplement or a medicament not only for prevention of disease such as insulin resistance, hyperinsulinism, Type 2 diabetes, hypertension, hyperlipidemia, arterial sclerosis and obesity, but also for fatigue recovery or endurance improvement by improving basal metabolism. In addition, a benzyl glucosinolate-containing composition for solving a third aspect is useful in the field of foodstuff or the like.

Disclosed is a method of topically applying a composition to skin. The method can include topically applying to skin the composition, where the composition comprises an extract from Kunzea ericoides, Quassia undulata, Khaya senegalensis, Biophytum petersianum, Detarium microcarpum, Crossopteryx febrofiga, Allophylus africanus, Burkea Africana, Nauclea latifolia, Bombax costatum, Buchanania reticulata, Melanorrhoea laccifera, Machilus odoratissimus, Spondias pinnata, Canthium dicoccum, Parinari annamensis, Aporosa tetrapleura, Knema globularia, Garcinia gaudichaudii, Randia dasycarpa, Capparis micrantha, or Garcinia benthami.

Disclosed is a method of topically applying a composition to skin. The method can include topically applying to skin the composition, where the composition comprises an extract from Kunzea ericoides, Quassia undulata, Khaya senegalensis, Biophytum petersianum, Detarium microcarpum, Crossopteryx febrofiga, Allophylus africanus, Burkea Africana, Nauclea latifolia, Bombax costatum, Buchanania reticulata, Melanorrhoea laccifera, Machilus odoratissimus, Spondias pinnata, Canthium dicoccum, Parinari annamensis, Aporosa tetrapleura, Knema globularia, Garcinia gaudichaudii, Randia dasycarpa, Capparis micrantha, or Garcinia benthami.

The present invention relates to a natural fermented composition of pollen using glacial snow water obtained by mixing pollen, such as bee pollen, pollen, and edible flowers, with glacial snow water and fermenting same, and a preparation method therefor. In the present invention, provided is a composition obtained by mixing glacial snow water having a pH of 7.5 to 8.8 and a density of 0.05-0.85 g/cm.sup.3 with one or more kinds of pollens selected from bee pollen, pollen, flower buds, floral leaves, and floral nectaries and fermenting the mixture for three months or longer without inoculation of microorganisms. The natural fermented composition of the pollens of the present invention contains a wide variety of nutritional and active ingredients, and can exhibit various effects. Especially, since the composition has excellent antioxidative effects, the composition may be used for foods and beverages, antioxidant drinks, etc.

The present invention relates to a natural fermented composition of pollen using glacial snow water obtained by mixing pollen, such as bee pollen, pollen, and edible flowers, with glacial snow water and fermenting same, and a preparation method therefor. In the present invention, provided is a composition obtained by mixing glacial snow water having a pH of 7.5 to 8.8 and a density of 0.05-0.85 g/cm.sup.3 with one or more kinds of pollens selected from bee pollen, pollen, flower buds, floral leaves, and floral nectaries and fermenting the mixture for three months or longer without inoculation of microorganisms. The natural fermented composition of the pollens of the present invention contains a wide variety of nutritional and active ingredients, and can exhibit various effects. Especially, since the composition has excellent antioxidative effects, the composition may be used for foods and beverages, antioxidant drinks, etc.