A61K38/01

INFANT NUTRITION WITH HYDROLYSED PROTEIN AND PALMITIC ACID
20170367395 · 2017-12-28 ·

The present invention relates to a composition for use in formulae for infants or young children comprising partially hydrolysed protein and an oil mix comprising palmitic acid wherein the palmitic acid esterified in the sn-2 position of triacylglycerols is in the amount of from 20% to 60% by weight of total palmitic acid. Furthermore, the invention relates to an infant formula comprising said composition and the use of said composition or infant formula.

Collagen peptide-based medicament compositions and devices and methods of production and use thereof

The present invention is in the fields of medicinal chemistry, biotechnology and pharmaceuticals. The invention provides compositions comprising one or more collagen mimetic peptides, optionally attached to one or more therapeutic compounds or one or more imaging compounds, for use in methods of treating, preventing, ameliorating, curing and diagnosing certain diseases and physical disorders in humans and veterinary animals, as well as methods of manufacturing such composition. The invention also provides medical devices comprising one or more such compositions of the invention. The invention also provides methods of use of such compositions and devices in treating and diagnosing certain diseases and physical disorders in humans and veterinary animals, including ocular diseases or disorders, skin diseases or disorders, certain cancers, particularly intraluminal cancers, gastrointestinal diseases or disorders, genitourinary tract diseases or disorders, fibrotic diseases/disorders and rheumatic diseases/disorders.

Pharmaceutical composition including laminin fragments to treat or prevent the disease, disorder or symptom of tooth dentin and/or dental pulp
20230190882 · 2023-06-22 ·

A tooth dentin, pulp or pulp tissue composition for treating or preventing a disease, disorder, or symptom of a tooth dentin and/or pulp or pulp tissue includes: (a) an integrin binding fragment of Laminin, the Laminin being selected from the group consisting of Laminin 511 and Laminin 411, the integrin binding fragment comprising an integrin-binding domain of the Laminin; and (b) a mixture of odontoblast and mineralized nodules secreted from the odontoblast. A coating density of the integrin binding fragment is 1 to 8 μg/cm.sup.2. The material (b) has been mixed with the material (a) in the composition so as to form pulp capping applicable to a tooth, such that the composition is able to treat or prevent the disease, disorder or symptom of the tooth dentin and/or pulp tissue including dental caries when applied to the tooth.

ANTIFUNGAL COMPOSITION COMPRISING ANTIFUNGAL PEPTIDE AND TERPENE ALCOHOL

A composition with an enhanced antifungal activity, which comprises peptides as a protamine hydrolysate and which is suitable for industrial application at a low cost, can be provided, by using a combination of a protamine hydrolysate and a terpene alcohol as an active ingredient of a composition having an antifungal activity.

ANTIFUNGAL COMPOSITION COMPRISING ANTIFUNGAL PEPTIDE AND TERPENE ALCOHOL

A composition with an enhanced antifungal activity, which comprises peptides as a protamine hydrolysate and which is suitable for industrial application at a low cost, can be provided, by using a combination of a protamine hydrolysate and a terpene alcohol as an active ingredient of a composition having an antifungal activity.

Composition comprising specific Lactobacillus helveticus strains and reducing food and/or respiratory allergy symptoms

A composition comprising specific Lactobacillus helveticus strains is provided for reducing the symptoms of allergies originating from food, respiratory or contact allergens. Preferably the composition reduces symptoms of allergies (secondary prevention) while also able to reduce sensitization (primary prevention).

Nutritional support to prevent and/or mitigate bone marrow toxicity from a cancerous tumor

The present invention relates to methods and immunonutritional compositions for preventing or mitigating paralysis of the bone marrow, caused by a tumor or neoplasm, between cycles of and after anti-cancer therapy, thereby attaining a better efficacy of the treatment. More particularly, the present invention relates to methods and immunonutritional compositions that can transiently preventing or moderating, bone marrow paralysis or neutropenia of a subject tumor-induced apoptosis or necrosis or other cell damage such that the innate and adaptive immune functions and normal physiology of the bone marrow are preserved, at least in part, which, in turn, lead to (i) a better tolerance and increased efficacy to treatment; (ii) transient augmentation or enhancement of immunocompetence of the immune cell; and (iii) optimization of the effects of and increase of immunocompetence of the immune cell weakened due to paralysis of the bone marrow, caused by a tumor or neoplasm.

Epithelial Treatment
20170326176 · 2017-11-16 ·

Products are described for treating epithelial tissues of the human or animal body including liquid compositions containing whole blood, or parts of blood including blood plasma, blood serum, blood platelets and growth factors derivable from blood. Other compositions disclosed include solid reservoirs of collagen or amniotic membrane into which whole blood or parts of blood have been absorbed. Methods of treatment using these compositions are described, in particular for treatment of ophthalmic disorders such as dry-eye and oral disorders such as dry mouth. A range of devices (1, 11, 31, 41, 51, 61, 71, 81, 91, 101) are described for sampling, mixing, storing and/or applying blood and compositions containing blood and parts of blood.