A closed and modular fluidic system composed of one or more acoustic elements and cell processing reagents. The system employs a cellular manufacturing process for producing cell and gene therapy therapeutics.

Activation of senescent stem cells in humans to promote wound healing and other therapies, and to promote general enhancement of health by application of non-thermal atmospheric pressure plasma (NTAPP) to tissues and body fluids such as blood. In particular, the targets of the NTAPP are stem cells. The products contained in NTAPP can affect the behavior of peripheral blood stem cells (PBSC) in blood, as well as stem cells found in tissues surrounding the blood in which said products are carried.

A skin treatment system that uses ultrasound devices, and more particularly, handheld devices with an ultrasound transducer used in combination with a continuous flow of serum carrying acoustically responsive media wherein acoustic energy transmitted from the transducer causes dimensional changes in the acoustically responsive media to create acoustic pressure peaks capable of loosening paracellular junctions in the skin to enhance penetration of serum into the skin.

Harvested stem cells are activated by treating them with an amplitude modulated laser beam having a wavelength lying in the range of 405 to 980 nanometers. The frequency of the laser beam is modulated within a range of 8 to 12 MHz. Using the activated stem cells, tissue can be repaired and regenerated by preparing the unactivated stem cells, treating the unactivated stem cells with an amplitude modulated laser beam having a pre-determined frequency for obtaining activated stem cells, administering the activated stem cells into a body containing the tissue, and using a homing beam to guide the activated stem cells within the body to the location of the tissue.

A spaser device comprises a graphene resonator and a carbon nanotube (CNT) gain element coupled via exciton-plasmon interaction. The graphene resonator may be a rectangular or square graphene nanoflake (GNF), and the CNT gain element may be characterised by chirality vector (n,m) selected such that the CNT has semiconducting properties. The CNT gain element may be illuminated using a light source having a photon energy corresponding with a first exciton energy (E.sub.22) of the CNT, whereby excitons having a second exciton energy (E.sub.11) less than the first exciton energy are generated in the CNT, and coupled to a surface plasmon (SP) mode of the graphene resonator. When the rate of generation of excitons having the second exciton energy exceeds a gain threshold, continuous spasing is established within the spaser device.

The present disclosure relates to improved methods for the preparation and platelet products for administration to subjects in need thereof

Disclosed herein is a method for regenerating retinal tissue which includes preparing a luminescent scaffold, implanting the luminescent scaffold in a portion of retina, for example subretinal area, emitting a green light from the luminescent nanoparticles in a luminescence phenomenon, and absorbing the emitted light by retinal cells for regenerating retinal tissue by stimulating the retinal cells. Moreover, preparing a luminescent scaffold may comprise synthesizing a plurality of luminescent particles, dispersing the luminescent particles in a polymeric matrix to form a luminescent composite, and electrospinning the luminescent composite to form the luminescent scaffold.

A gold nanocluster of the formula Au.sub.16(RGDC).sub.14, wherein RGDC is arginine-glycine-aspartic acid-cysteine, and methods for synthesis, are described. The gold nanocluster effectively produces Type I ROS and functions as photosensitizer, and has utility in applications such as, but not limited to, biomedical applications and photocatalysis. The gold nanocluster may be useful in photodynamic therapy (PDT) in cells and tissues for treating diseases such as certain cancers.

The present invention is directed toward the use of non-thermal plasma-treated liquids as treatment options for herpes keratitis.

A method of treating atherosclerosis comprises removing AGE-modified cells from a patient. The AGE-modified cells include erythrocytes, intima cells, endothelial cells, smooth muscle cells, macrophages, and foam cells. A variety of techniques, such as ultrasound and binding with an anti-AGE antibody, may be used to identify and remove the AGE-modified cells.