The present disclosure relates to topical compositions and methods for the treatment of radiation dermatitis. The compositions include a cannabinoid and an oil comprising at least 1 wt % of at least one molecule containing an aliphatic chain with at least one cyclopropyl or cyclopropenyl group, such as a cyclopropene fatty acid or a cyclopropane fatty acid. The compositions can also include other components such as stabilizers, thinners, thickeners, fragrances, moisturizers, emollients; and components that provide anti-irritation or anti-inflammatory properties to the compositions.

The present disclosure relates to topical compositions and methods for the treatment of radiation dermatitis. The compositions include a cannabinoid and an oil comprising at least 1 wt % of at least one molecule containing an aliphatic chain with at least one cyclopropyl or cyclopropenyl group, such as a cyclopropene fatty acid or a cyclopropane fatty acid. The compositions can also include other components such as stabilizers, thinners, thickeners, fragrances, moisturizers, emollients; and components that provide anti-irritation or anti-inflammatory properties to the compositions.

A soothing lip balm composition includes a wax binder component, which includes at least two compounds selected from a C.sub.8-C.sub.30 fatty acid, esterified C.sub.8-C.sub.30 fatty acid, and C.sub.8-C.sub.30 fatty alcohols; a complex fat component, which includes at least three different compounds selected from C.sub.8-C.sub.30 fatty acids; an organic compound component, which includes at least three compounds selected from 2,5-dimethoxy-p-cymene, cumene, thymol methyl ether, 2,6-diisopropylanisole, decanal, and 1,2,2,3-tetramethylcyclopent-3-enol; and an enzymatic component, which includes cysteine endopeptidase.

A soothing lip balm composition includes a wax binder component, which includes at least two compounds selected from a C.sub.8-C.sub.30 fatty acid, esterified C.sub.8-C.sub.30 fatty acid, and C.sub.8-C.sub.30 fatty alcohols; a complex fat component, which includes at least three different compounds selected from C.sub.8-C.sub.30 fatty acids; an organic compound component, which includes at least three compounds selected from 2,5-dimethoxy-p-cymene, cumene, thymol methyl ether, 2,6-diisopropylanisole, decanal, and 1,2,2,3-tetramethylcyclopent-3-enol; and an enzymatic component, which includes cysteine endopeptidase.

Provided herein are compositions, formulations, and (e.g., oral) dosage forms comprising a compound of Formula (I). In specific instances, such compositions comprise an emulsifier, a solubilizer, a polyethylene glycol, a surfactant, and an antioxidant. In some instances, such compositions are useful for the treatment of fibrosis, cancer, and/or chronic inflammation.

The present disclosure provides compositions and methods for acidic compositions for use in optimizing the genital microbiome of a user or sexual partners of that user. The compositions may comprise a prebiotic oligosaccharide, a metal co-factor, and an essential oil comprising bornyl acetate. The compositions support the genital microbiota and are useful for, for example, hydrating, lubricating, cleaning, and/or decreasing irritation or inflammation of the urogenital and/or anogenital region of a subject, and/or enhancing the beneficial genital microbiota of a subject. Such compositions are useful before, during, and/or after sexual and/or reproductive activity. Furthermore, the compositions may have minimal or beneficial effect on gametes.

The present invention relates to antimicrobial formulations. More particularly, the invention relates to monovalent copper-containing and/or monovalent copper-generating products for healing wounds and burns, and particularly for chronic wounds, prevention of wound infections and infections in various implants as well as medical/surgical devices.

The present invention relates to antimicrobial formulations. More particularly, the invention relates to monovalent copper-containing and/or monovalent copper-generating products for healing wounds and burns, and particularly for chronic wounds, prevention of wound infections and infections in various implants as well as medical/surgical devices.

Disclosed are compositions, methods of treatment using the compositions and methods of preparing the compositions for the treatment of acne vulgaris. The compositions include succinic acid and an API selected from the group consisting of salicylic acid, azelaic acid, picolinic acid, benzoyl peroxide, antibiotic, retinoid and combinations thereof in a pharmaceutically acceptable preparation. The compositions that include the combination of succinic acid and another API produce improved efficacy in treating acne vulgaris.

Disclosed are compositions, methods of treatment using the compositions and methods of preparing the compositions for the treatment of acne vulgaris. The compositions include succinic acid and an API selected from the group consisting of salicylic acid, azelaic acid, picolinic acid, benzoyl peroxide, antibiotic, retinoid and combinations thereof in a pharmaceutically acceptable preparation. The compositions that include the combination of succinic acid and another API produce improved efficacy in treating acne vulgaris.