The present invention involves the application of Semen Ziziphi Spinosae oil in the preparation of drugs for treating medicinal insomnia. Semen Ziziphi Spinosae oil has a therapeutic effect on insomnia caused by ephedrine, prednisone and other drugs, and Semen Ziziphi Spinosae oil that is prepared within the pressing temperature of 80 to 100 C. has the best efficacy for treating medicinal insomnia.

The invention relates to methods of producing extracts from cannabis plant material, where the extracts comprise cannabinoids and terpenes. The methods comprise extracting fresh or dried plant material with a cold organic solvent. The methods allow for the extraction of cannabinoids and terpenes, while leaving behind impurities such as waxes and chlorophyll that are commonly found in extractions with room temperature (RT) or warm solvent extraction methods. The methods can produce extracts having more than 90% cannabinoids.

The present disclosure relates to pharmaceutical compositions including an active substance with antimicrobial, antiviral, and immunoistimulatory activities. The disclosure further provides methods of treating bacterial or viral infections and methods of enhancing immune function using the active substance.

A method to process microalgae biomass and produce high-value chemicals from microalgae biomass is disclosed. The method uses the same biomass cells to extract more than one component such as lipids, water-soluble chemicals, carotenoids, polysaccharides and algae meal. The method is a sequence of physical and chemical treatments. Water soluble polysaccharides produced by the method exhibit properties of low viscosity at low shear thinning. A method for extracting dietary fiber from microalgal biomass is disclosed. Compositions of water-soluble polysaccharides that are fermented slowly by colon microbiota with less gas production than commercial dietary fiber FOS are disclosed. The present inventions described herein provide a method of improving colon health by increasing butyrate during a microalgal dietary fiber fermenting process by colonic microbiota.

The present invention refers to a process for preparing a salt solution comprising sodium chloride and extracts of parts of officinal plants, preferably extracts of olive tree leaves; the invention is further directed to the salt solution itself, optionally enriched in iodine, particularly in a spray formulation, and to its uses as food supplement, as flavour enhancer for reducing salt consumption and for preventing cardiovascular and renal diseases, osteoporosis, and diseases related to salt abuse and/or iodine insufficiency in the diet.

The cosmetic use of one or more absolute(s) obtained from magnolia, juniper or violet for depigmenting the skin.

A novel grape seed extract is enriched in procyanidins, has total polyphenols of less than 70%, and has a low degree of polymerization (dp). Other fractions of the extract have minimal polyphenols, fiber, and protein, but contain more than 90% sugars. In some specific examples, the individual extracts are obtained by sequential ultrafiltration of a water extract of the grape seeds. A first ultrafiltration provides a first permeate (Fraction A) enriched in sugars which is useful as a flavorant, and a first retentate. The first retentate is reconstituted and subjected to a second ultrafiltration at a higher molecular weight cutoff to produce a second permeate (Fraction B) that is enriched in low molecular weight polyphenols, and a second retentate (Fraction C) that is enriched in seed fiber. The Fractions are individually suitable for different nutraceutical products, or can be combined with each other in any combination and/or with other nutraceutical agents to enhance vascular and cognitive health.

Cannabinoids, in particular CBD and CBDA and their acid derivatives are provided for use as an active pharmaceutical substance in the treatment of nausea, vomiting, emesis, motion sickness. In particular extracts of cannabis plants are presented which are rich in these substances and suitable for pharmaceutical use.

A pharmaceutical or cosmetic composition is provided. The composition includes an Indigo Naturalis or Indigo-producing plant extract, for inhibiting Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus. A method of inhibiting Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus, is also provided. The method includes contacting a cell with an effective amount of an Indigo Naturalis or Indigo-producing plant extract.

Concentrated cannabis extract is obtained from raw cannabis plant material using a mixed solvent extraction process. The cannabis is soaked and agitated in a chilled mixture of butane, propane and isobutane. After removing the solid plant material, the remaining solvent mixture, now with dissolved extracts, is heated to remove the solvents. The remaining, viscous oil is then heated in a vacuum oven to purge the traces of solvent and result in a brittle shatter.