The invention relates to an extract of Santolina chamaecyparissus, to a process for preparing said extract, to a composition comprising it, and to its use a preservative, particularly as antioxidant, bactericidal and/or fungicidal.

A method of isolating at least one sphingolipid portion selected from a sphingoid base portion, a ceramide portion, a glycosphingolipid portion or a phosphosphingolipid portion from Cordyceps, in particular from wild-type Cordyceps, allows for obtaining sphingolipid portions having an increased amount of one of sphingoid bases, ceramides, glycosphingolipids or phosphosphingolipids. The sphingolipid portions isolated contained significant amounts of sphingolipids not reported so far, and possess exceptional immunosuppressive activities. A method of treating a subject suffering from an inflammatory disease like an autoimmune disease or an allergic disease includes administering sphingolipids isolated from Cordyceps, in particular from wild-type Cordyceps. A method of treating a subject suffering from an inflammatory disease includes administering certain sphingolipids to the subject. Still further in accordance with the present invention is a composition, in particular a pharmaceutical composition comprising at least one sphingolipid portion.

The present invention relates to a method of identifying and preferably quantifying at least one sphingolipid, in particular the sphingolipid portion in wild-type Cordyceps or Cordyceps derivates. A further aspect relates to a method of identifying wild-type Cordyceps in a Cordyceps sample as well as for identifying Cordyceps derivates in a Cordyceps sample. The methods of the present invention, thus, allow for determining the quality and safety of Cordyceps products and for advantageously differentiating between wild-type Cordyceps and Cordyceps derivates via the ratio and/or presence of certain sphingolipids especially suitable as markers.

A novel grape seed extract is enriched in procyanidins, has total polyphenols of less than 70%, and has a low degree of polymerization (dp). Other fractions of the extract have minimal polyphenols, fiber, and protein, but contain more than 90% sugars. In some specific examples, the individual extracts are obtained by sequential ultrafiltration of a water extract of the grape seeds. A first ultrafiltration provides a first permeate (Fraction A) enriched in sugars which is useful as a flavorant, and a first retentate. The first retentate is reconstituted and subjected to a second ultrafiltration at a higher molecular weight cutoff to produce a second permeate (Fraction B) that is enriched in low molecular weight polyphenols, and a second retentate (Fraction C) that is enriched in seed fiber. The Fractions are individually suitable for different nutraceutical products, or can be combined with each other in any combination and/or with other nutraceutical agents to enhance vascular and cognitive health.

Methods of extraction of one or more polyphenolic compounds from pomace are described. The invention also provides uses of the extracts in the fortification of fruit juice, vegetable juice and foods, and as an antioxidant, an anti-inflammatory and an antifungal.

Cannabinoids, in particular CBD and CBDA and their acid derivatives are provided for use as an active pharmaceutical substance in the treatment of nausea, vomiting, emesis, motion sickness. In particular extracts of cannabis plants are presented which are rich in these substances and suitable for pharmaceutical use.

The invention provides a method for extracting active therapeutic components from plant materials of the cyclanthera pedata plant which comprises immersing said plant material containing active components and selected from the group consisting of fruits, flowers, leaves, stems, twigs, bark, wood, buds, seeds, roots, and pods in a solvent for a period of time of about 30 minutes to about 10 hours to achieve transfer of active components from the plant material to the solvent, separating the solvent containing active components from the plant material, and evaporating or distilling the solvent to produce a concentrated fraction containing active components. The invention further includes compositions and therapeutic formulations of such extracts to treat hypercholesterolemia and other high lipid related diseases.

A major object of the present technology is to provide a technology for obtaining an aloe extract which has an excellent processability into foods and contains sufficient amounts of -sitosterol and aloe-derived dietary fibers as functional components. The present technology provides a method for manufacturing an aloe extract containing -sitosterol, phospholipids, and dietary fibers which involves carrying out: a homogenization step for homogenizing an aloe mesophyll solution; an enzymatic degradation step for adding a polysaccharide-degrading enzyme to the homogenized aloe mesophyll solution and degrading polysaccharides contained in the aforementioned homogenized aloe mesophyll solution; and a membrane filtration step for membrane-filtering the enzyme-degraded aloe mesophyll solution with a microfiltration membrane or an ultrafiltration membrane and recovering the retentate fraction as an aloe extract.

Provided herein are methods for treating a patient with ADHD and anxiety, comprising administering to the patient a therapeutically effective amount of psilocybin. The disclosure also provides methods for treating ADD and reducing symptoms of Tourette Syndrome using psilocybin. Additionally, methods of cultivation, extraction, and purification of psilocybin mushrooms are described. The psilocybin is obtained from mushroom species such as Psilocybe cubensis, Psilocybe cyanescens, Psilocybe semilanceata, or Psilocybe azurescens. The methods involve tissue culture, agar inoculation, grain-to-grain transfer, bulk substrate inoculation, and fruiting. Extraction and purification steps include harvesting, drying, grinding, solvent extraction, filtration, evaporation, and cryogenic separation.

An orally administered cannabis pill tailored for medicinal and recreational applications and consumption is disclosed. The pill contains decarboxylated cannabis and in some embodiments can include flavoring agents, mineral and vitamin supplements, and Lecithin. The pill is in the form of a gelatin capsule and disintegrates within the human body for providing cannabis advantages without affecting lung health. The invention also includes a method for producing the pill and includes sourcing of fresh and organic cannabis flowers containing cannabinoids. The flowers are subjected to heat and pressure to extract essential oils and produce concentrated cannabis extract discs. Decarboxylation is done to convert THCA into psychoactive THC. Subsequently, the decarboxylated cannabis extract is finely ground into a powder and encapsulated within size 00 gelatin capsules.