A61K2800/10

Method for purification of liquid compositions containing at least one sphingolipid

The present invention relates to a method for purification of liquid compositions containing at least one sphingolipid and the use of a specific clay mineral for the purification of such liquid compositions.

HYDRATABLE COSMETIC COMPOSITION

The present invention is directed to a cosmetic composition precursor that is rapidly hydratable and conducive to creating a personalized end-product. This invention thus relates to a cosmetic composition precursor having fatty acid, inorganic base, and high HLB surfactants and methods of using said precursors in creating the end-product. The invention also relates to end-use compositions made from the hydratable cosmetic composition precursor of the invention.

CROSS-LINKED COMPOSITIONS AND THEIR USE

The present disclosure relates to chemical processes and more particular to chemical processes for forming cross-linked compositions and their use.

17-hydroxyprogesterone ester-containing oral compositions and related methods

The present invention provides for bioavailable oral dosage forms containing esters of 17-hydroxyprogesterone as well as related methods. The oral dosage forms can be formulated for pregnancy support and can include a therapeutically effective amount of an ester of 17-hydroxyprogesterone and a pharmaceutically acceptable carrier. In another embodiment, a pharmaceutically acceptable oral dosage form for pregnancy support is provided. The pharmaceutically acceptable oral dosage can include a therapeutically effective amount of an ester of 17-hydroxyprogesterone and a pharmaceutically acceptable carrier. The oral dosage form can, when measured using a USP Type-II dissolution apparatus in 900 mL of deionized water with 0.5 (w/v) of sodium lauryl sulfate at 50 RPM at 37° C., release at least 20 wt % of the dose of the ester of 17-hydroxyprogesterone after 60 minutes, or in the alternative release at least 20 wt % more after 60 minutes than an equivalently dosed oral dosage form without the carrier.

ARTICLES OF MANUFACTURE WITH DEGRADABLE DELIVERY PARTICLES BASED FROM AMINE CONTAINING NATURAL MATERIALS
20230072724 · 2023-03-09 · ·

An article of manufacture is described comprising the combination of an adjunct material and a delivery particle. The delivery particle comprising a benefit agent core material and a shell encapsulating the core material is described, along with a process for forming such a delivery particle and articles of manufacture. The shell is the reaction product of: i) an isocyanate or acid chloride or acrylate with ii) an amine-containing natural material having free amino moieties, and iii) an α, β-unsaturated compound, the α, β-unsaturated compound forming C—N covalent bonds with the amine moieties of the natural material. The delivery particle of the invention has improved release characteristics, with enhanced degradation characteristics in OECD test method 301B.

Chitosan-pluronic complex and nano-carrier comprising same

The present invention relates to a transdermal nano-carrier and, more specifically, to a nano-carrier having a chitosan-based nano-sponge structure. According to the present invention, as a nano-carrier having enhanced transdermal delivery on the basis of a complex containing chitosan is provided, it is possible to effectively deliver drugs, cosmetic materials, etc. into the skin.

Silicone polymer

Provided is a polymer of the formula: ##STR00001##
and compositions comprising the same. The polymers comprise a cyclic unsaturated group (Z.sup.3) within the siloxane polymer backbone. The polymers have been found to exhibit good thermal conductivity and may find utility in a variety of applications.

Surfactant for water-in-oil emulsion
11633333 · 2023-04-25 · ·

The present invention relates to a water-in-oil surfactant consisting of a mixture of compounds of formula (I): ##STR00001##
wherein the compound of formula (I) has an average degree of polymerisation n of between 4 and 6,
R1, R2 and R3 being, independently of one another, a hydrogen atom or a group R4 derived from at least one carboxylic acid,
the carboxylic acid being 12-hydroxystearic acid or a mixture of 12-hydroxystearic acid and ricinoleic acid. The present invention also relates to a surfactant composition and to a cosmetic composition comprising this surfactant.

Plant extracts with anti-diabetic and other useful activities

This invention relates to plant extracts containing nutritionally beneficial or medicinally active compounds. Some of these extracts, or the purified compounds contained therein, may be used for the nutritional support, prevention, treatment, or possible cure of various metabolic and other diseases and disorders in human beings and animals, including type 1 and type 2 diabetes, by regulating insulin signaling. This regulatory effect may include modulations of the levels and/or activity of the Insulin Receptor (IR), the Insulin-like Growth Factor (IGF) Receptor, and/or the Insulin Receptor Substrate (IRS) proteins in cells and tissues in the body.

Additive composition for improving feel on skin of cosmetics material

The present invention relates to an additive composition for cosmetics material containing vitamin-C, the additive composition improving the feel on the skin of vitamin-C which is an anti-oxidant. High vitamin-C content can cause stinging skin irritation or be sticky to the touch, but the additive composition according to the present invention, when used in cosmetics composition with high vitamin-C content, due to the oil, can reduce irritation and stickiness, as well as provide a moisturizing effect.