A novel fibrinogen-based tissue adhesive patch is disclosed. The patch comprises a backing made from a non-permeable biocompatible polymer film into which a fibrinogen-based sealant is incorporated. In preferred embodiments of the invention, the biocompatible polymer film comprises units of a biocompatible block copolymer such as a polyethylene glycol-polycaprolactone-DL-lactide copolymer connected by urethane linkages, and the fibrinogen-based sealant comprises fibrinogen, thrombin, and CaCl.sub.2. In contrast to similar patches known in the art, the polymer backing serves to seal the tissue to which the patch is applied, and the sealant acts only to bind the patch to the affected tissue. The patch does not include any mesh, woven, or non-woven component. Methods of production and use of the patch are also disclosed.

The present invention relates to an antibacterial dressing and a method for preparing the same. According to the present invention, there are provided an antibacterial dressing containing a rapid cell membrane-penetrating component that exhibits excellent bactericidal and antibacterial activities by disrupting the structure and synthesis of protein and nucleic acid, and a method for preparing the same.

The present invention relates to an antibacterial dressing and a method for preparing the same. According to the present invention, there are provided an antibacterial dressing containing a rapid cell membrane-penetrating component that exhibits excellent bactericidal and antibacterial activities by disrupting the structure and synthesis of protein and nucleic acid, and a method for preparing the same.

Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon.

A transfer sheet including a support layer including a porous material, and a thin-film layer supported by the support layer and having a thickness of 5000 nm or less. The transfer sheet has a dry adhesion strength of 100 mN or more, and a wet adhesion strength of lower than the dry adhesion strength and 230 mN or less, where the dry adhesion strength is an adhesion strength between the support layer and the thin-film layer while the support layer and the thin-film layer are dry, and the wet adhesion strength is an adhesion strength between the support layer and the thin-film layer while the support layer and the thin-film layer are wet.

Systems and apparatuses for administering reduced pressure treatment to a tissue site include a reduced pressure source, a drape having a plurality of projections for contacting the tissue site, and an adhesive connected to at least a portion of the drape for sealing the drape to a portion of a patient's intact epidermis.

Systems and apparatuses for administering reduced pressure treatment to a tissue site include a reduced pressure source, a drape having a plurality of projections for contacting the tissue site, and an adhesive connected to at least a portion of the drape for sealing the drape to a portion of a patient's intact epidermis.

This invention, the Infection Resistant Bandage System, is an apparatus and method that uses Ultraviolet C (UVC) and B (UVB) band light to prevent the formation of bacterial biofilms that complicate wound management. The device is a bandage that irradiates the wound site with light at wavelengths of 120 to 270 nm to detect, prevent, and inactivate microorganisms. The device includes a control unit that manages the UV light irradiation protocol, the wavelength selection, the irradiation on-time, and the identification of the target bacteria. A Deep Learning Neural Network directs the irradiation protocol and the fluorescence based bacteria detection process. The device is useable in a home, clinical, or emergency field environment. The device efficacy of preventing and eradicating bacterial biofilms is 99%. There are no chemical or antibacterial substances associated with the process.

This invention, the Infection Resistant Bandage System, is an apparatus and method that uses Ultraviolet C (UVC) and B (UVB) band light to prevent the formation of bacterial biofilms that complicate wound management. The device is a bandage that irradiates the wound site with light at wavelengths of 120 to 270 nm to detect, prevent, and inactivate microorganisms. The device includes a control unit that manages the UV light irradiation protocol, the wavelength selection, the irradiation on-time, and the identification of the target bacteria. A Deep Learning Neural Network directs the irradiation protocol and the fluorescence based bacteria detection process. The device is useable in a home, clinical, or emergency field environment. The device efficacy of preventing and eradicating bacterial biofilms is 99%. There are no chemical or antibacterial substances associated with the process.

Systems and apparatuses for administering reduced pressure treatment to a tissue site include a reduced pressure source, a drape having a plurality of projections for contacting the tissue site, and an adhesive connected to at least a portion of the drape for sealing the drape to a portion of a patient's intact epidermis.