Medical dressings and methods of using same. The medical dressing can include a fluid management article. The fluid management article can include a fibrous substrate and porous polymeric particles. At least 50% of the porous polymeric particles are bound to the fibrous substrate. Methods of using the medical dressings can include applying the medical dressing to the target site, such that the fluid management article is in fluid communication with the target site.

Medical dressings and methods of using same. The medical dressing can include a fluid management article. The fluid management article can include a fibrous substrate and porous polymeric particles. At least 50% of the porous polymeric particles are bound to the fibrous substrate. Methods of using the medical dressings can include applying the medical dressing to the target site, such that the fluid management article is in fluid communication with the target site.

A diaper for collecting biological samples relates to light industry, and more particularly to a diaper for use in medical examinations and in diagnosing a person's state of health on the basis of an analysis of secretions and/or excreta of the individual. The technical aim of the invention is to create a diaper for the quick and efficient collection of biological samples, the use of which is not restricted by a particular type of indicator substance, and the structural characteristics of which provide for simple, convenient and efficient use. The present diaper (1) for collecting biological samples consists of at least a secretion and/or excreta absorbing base and a detachable absorbing layer (3). The secretion and/or excreta absorbing base of the diaper is provided with at least one through-hole (2). The hole is hermetically sealed on the outside by a sampling element consisting of the detachable absorbing layer and also of a water-impermeable layer (4) and a retaining layer (5).

An adhesive formulation is provided for use in a film wound dressing. The adhesive formulation includes a medical-grade adhesive and an antimicrobial substance. This adhesive formulation may be coated onto one or more surfaces of a medical-grade transparent film suitable for a wound dressing. The antimicrobial material may be a silane quaternary ammonium salt. The silane quaternary ammonium salt may comprise 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride. The 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride may constitute about 72% of the silane quaternary ammonium salt. The medical-grade adhesive may comprise an acrylic adhesive. Further, the adhesive formulation may include about 0.01% to about 60% of the antimicrobial substance. The transparent film dressing may further include a release liner applied over the coated side(s) of the transparent film. The transparent film may comprise polyurethane.

An adhesive formulation is provided for use in a film wound dressing. The adhesive formulation includes a medical-grade adhesive and an antimicrobial substance. This adhesive formulation may be coated onto one or more surfaces of a medical-grade transparent film suitable for a wound dressing. The antimicrobial material may be a silane quaternary ammonium salt. The silane quaternary ammonium salt may comprise 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride. The 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride may constitute about 72% of the silane quaternary ammonium salt. The medical-grade adhesive may comprise an acrylic adhesive. Further, the adhesive formulation may include about 0.01% to about 60% of the antimicrobial substance. The transparent film dressing may further include a release liner applied over the coated side(s) of the transparent film. The transparent film may comprise polyurethane.

The present invention relates to a mattress for preventing and treating bedsores comprising a main body (1) and an exchangeable element (2, 3, 4), said exchangeable element (2, 3, 4) comprising an absorbent composition (7) and a disinfectant composition (8).

The present invention also relates to a method for manufacturing such a mattress, and comprising the following steps: production of the main body (1), covered with a cover (5), in particular in plasticized jersey, with a housing for at least one exchangeable element (2, 3, 4), production of an exchangeable element (2, 3, 4) in honeycomb cardboard or viscoelastic cellular foam, deposition of an absorbent composition (7) in the exchangeable element, deposition of a disinfectant composition (8) on the absorbent composition, arrangement of an envelope (11) around the exchangeable element (2, 3, 4), made in particular of a permeable nonwoven textile, placement of the exchangeable element (2, 3, 4) in the car responding housing of the main body (1).

The present invention relates to a therapeutic compound comprising: an agent that inhibits the activity of at least one gene selected from the group consisting of MAF, MEOX2, SIX2 and homologues thereof having at least 50% identity with said genes and/or an agent that enhances the activity of at least one gene selected from the group consisting of CREB5, E2F1, EGR2, HIC1, IRF7, JUN, MYC, SRF, STAT4, TCF4, FOXS1, GLI1, SOX9 and homologues thereof having at least 50% identity with said gene for use in the treatment of wounds, preferably chronic wounds.

The present invention relates to a therapeutic compound comprising: an agent that inhibits the activity of at least one gene selected from the group consisting of MAF, MEOX2, SIX2 and homologues thereof having at least 50% identity with said genes and/or an agent that enhances the activity of at least one gene selected from the group consisting of CREB5, E2F1, EGR2, HIC1, IRF7, JUN, MYC, SRF, STAT4, TCF4, FOXS1, GLI1, SOX9 and homologues thereof having at least 50% identity with said gene for use in the treatment of wounds, preferably chronic wounds.

Methods and apparatus for a biodegradable multi-layer device suitable for medical applications are provided, wherein the device is formed from multiple film-layers configured to have different characteristics from one another such as different release profiles for therapeutic agents, adhesive properties, stiffness properties, and solubility properties. The film-layers may include a solid fibrinogen component. A device having multiple film-layers may take a non-adherent form during delivery to a target location within or on tissue, and thereafter may be exposed to moisture to take an adherent form on the tissue. The device may include a number of additives, including materials to improve the mechanical properties of the device, or one or more therapeutic or contrast agents.