The present invention provides threads of hyaluronic acid, and/or derivatives thereof, methods of making thereof and uses thereof, for example, in aesthetic applications (e.g., dermal fillers), surgery (sutures), drug delivery, etc.

The present invention provides threads of hyaluronic acid, and/or derivatives thereof, methods of making thereof and uses thereof, for example, in aesthetic applications (e.g., dermal fillers), surgery (sutures), drug delivery, etc.

Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.

An absorbable medical article comprising: an absorbable polymeric substrate; and an absorbable composition disposed on at least a portion of a surface of the substrate, wherein the absorbable composition comprises: (i) at least one absorbable coating polymer distinct from the substrate and (ii) a colorant that is miscible with the absorbable coating polymer.

There is provided a method for decreasing leakage of matter from an object to a surrounding, said object being coated with a coating at least partially applied on the object, said coating comprising an at least partially covering layer comprising silver, said object optionally comprising area(s) without said layer, said coating comprising metal particles applied on the layer and optionally on areas without said layer, said metal particles comprising palladium and at least one metal selected from the group consisting of gold, ruthenium, rhodium, osmium, iridium, niobium, neodymium and platinum and wherein the amount of the metal particles is in the interval 0.01-8 μg/cm.sup.2. Advantages include that leakage of matter such as latex allergens of metal ions can be reduced while the coating is both biocompatible and antimicrobial. Further, the blood clotting can be reduced.

There is provided a method for decreasing leakage of matter from an object to a surrounding, said object being coated with a coating at least partially applied on the object, said coating comprising an at least partially covering layer comprising silver, said object optionally comprising area(s) without said layer, said coating comprising metal particles applied on the layer and optionally on areas without said layer, said metal particles comprising palladium and at least one metal selected from the group consisting of gold, ruthenium, rhodium, osmium, iridium, niobium, neodymium and platinum and wherein the amount of the metal particles is in the interval 0.01-8 μg/cm.sup.2. Advantages include that leakage of matter such as latex allergens of metal ions can be reduced while the coating is both biocompatible and antimicrobial. Further, the blood clotting can be reduced.

Bioresorbable medical devices, such as stents, scaffolds and other medical devices implantable in human and animal bodies, in which galvanic couples are formed. The devices include bioresorbable amalgamates, wires, laminates, layered structures or combinations thereof. Also, methods of manufacturing the devices, including laminating, folding, 110 braiding, weaving, crocheting or cold spraying of materials with different galvanic potentials Also, machining of amalgamated materials using electrical discharge machining.

Bioresorbable medical devices, such as stents, scaffolds and other medical devices implantable in human and animal bodies, in which galvanic couples are formed. The devices include bioresorbable amalgamates, wires, laminates, layered structures or combinations thereof. Also, methods of manufacturing the devices, including laminating, folding, 110 braiding, weaving, crocheting or cold spraying of materials with different galvanic potentials Also, machining of amalgamated materials using electrical discharge machining.

Cosmetic threads for reducing wrinkle size include at least one synthetic collagen fiber that wells after placement under the skin.

Cosmetic threads for reducing wrinkle size include at least one synthetic collagen fiber that wells after placement under the skin.