A novel high tensile strength semi-absorbable composite suture with minimized non-absorbable mass. The suture has a core made from a bioabsorbable polymer. The core is covered by a braided sheath. The braided sheath is made from an absorbable yarn and a bioabsorbable yarn. The bioabsorbable yarn is made from a least one filament of a bioabsorbable polymer. The nonabsorbable yarn is made from at least one filament of ultra high molecular weight polyethylene.

A biomaterial for suturing comprising a physiologically compatible support material coated with a cellular population with proliferative and/or differentiation capacity, characteristics which facilitate the regeneration of the sutured tissue. This biomaterial for suturing not only brings together the two edges of an open wound, but also contributes actively to the healing process, thereby accelerating the tissue repair process. Also disclosed are methods for making the biomaterial and methods for using the biomaterials in therapy.

A suture anchor includes a threaded anchor body having a first central bore in communication with a second central bore. The suture anchor includes an internal eyelet formed of a loop disposed at least partially inside the first central bore. The ends extending from the loop are tied together to form at least one knot which is housed in the second central bore provided at the distal end of the anchor body. The knot increases the pullout strength of the suture even in soft bone, provides increased suture fixation, and eliminates the anchor pull back.

An embodiment includes a system comprising: a substrate of a medical device; an un-foamed polyurethane coating directly contacting the substrate and fixedly attached to the substrate; a thermoset polyurethane shape memory polymer (SMP) foam, having first and second states, which directly contacts the polyurethane coating and fixedly attaches to the polyurethane coating; wherein the polyurethane coating fixedly attaches the SMP foam to the substrate. Other embodiments are described herein.

A method of reducing surgical site infection (SSI), using a coated medical device having a tissue penetrating surface and an abradable coating on the medical device comprising at least one antimicrobial agent in the coating.

A suture made of a woven braid of fibers is provided. The suture includes: at least one first end; at least one second end comprising a colorable material wherein the second end has been colored a single color along an entire length of the second end; and at least one third end comprising a colorable material wherein only a portion of the third end is colored a continuous color. In another embodiment, a method of manufacture of a suture is provided. The method includes: braiding an elongate suture from a first end, a second end comprising a colorable material, and a third end comprising a colorable material; coloring the second end a single first color along an entire length of the second end; coloring only a first portion of the third end a second color.

A suture made of a woven braid of fibers is provided. The suture includes: at least one first end; at least one second end comprising a colorable material wherein the second end has been colored a single color along an entire length of the second end; and at least one third end comprising a colorable material wherein only a portion of the third end is colored a continuous color. In another embodiment, a method of manufacture of a suture is provided. The method includes: braiding an elongate suture from a first end, a second end comprising a colorable material, and a third end comprising a colorable material; coloring the second end a single first color along an entire length of the second end; coloring only a first portion of the third end a second color.

Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.

Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.

Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a cord that is flexible and elongated defining a length. The cord may include a core having a porous surface and a porosity-reducing element on at least a portion of the core.