An implantable biopolymer scaffold includes at least one braided strand comprising high strength collagen fibers and synthetic fibers, wherein the collagen fibers have a greater cross-sectional deformability than the synthetic fibers.

Technologies for fibers with nanotechnology is disclosed. In the illustrative embodiment, a preform is 3D printed with one or more sacrificial cores and one or more hollow channels. The preform is drawn into a fiber, and one or more metal core(s) is inserted into the hollow channel during the fiber draw. The fiber is then heated, breaking up the sacrificial cores into balls through capillary action. The fiber can be etched, exposing the balls made up of the sacrificial cores. The balls can be selectively etched, exposing the metal core(s) of the fiber. Additional embodiments are disclosed.

The disclosed inventions relate to an improved bioceramic coated product and methods of characterizing coated products. More specifically, the disclosed inventions relate to an improved bioceramic coated product comprising bioceramic particles that has a homogeneous or uniform application that should reliably provide consistent healing response properties after implantation. The consistent healing responses may include enhanced osteoconductive properties or bone growth, antimicrobial activity, and/or angiogenic activity.

The disclosed technology includes a bioabsorbable material configured to be delivered to tissue. The material includes a shape-memory polymer compressible in a delivery configuration and configured to swell within a predetermined period of time. The shape-memory polymer includes one or more functional groups for reversible bonding between adjacent functional groups to transition between an approximately linear polymer and an approximately non-linear polymer upon exposure to a stimulation.

Suture materials for producing medical devices are provided. The suture materials can include natural fibers, and can be suitable for making multifilament sutures and surgical meshes comprising multifilament sutures as examples of medical devices. The multifilament suture can include a plurality of filaments combined together according to a twined pattern, and at least one filament of the plurality of filaments can include natural fibers, synthetic fibers, or mineral-based fibers. A suture device can include the multifilament suture combined with a suture needle. The multifilament suture can be coated with a biocompatible coating, such as a bioactive agent, and/or include a first set of filaments that includes natural fibers and a second set of filaments that includes natural fibers that are different from the natural fibers of the first set of filaments, synthetic fibers or mineral-based fibers, for instance.

A surgical thread has a thread body with a self-sticking material configured to stick to a biological tissue upon contact with the biological tissue and/or an activator. An alternative surgical thread has a thread body and a coating that at least partially surrounds the thread body. The coating has or is made of a self-sticking material configured to stick to a biological tissue upon contact with the biological tissue and/or an activator. A surgical device or surgical kit can include the surgical threads.

The present invention is directed to an implantable medical device, comprising: a device body, with at least a portion of said body coated by a sensing coating that comprises an echogenic material or a radiopaque material, or combinations thereof, said sensing coating configured to dissolve or swell in presence of at least one infection biomarker; wherein a portion of said sensing coating is covered by a protective film, forming a protected portion, said protected portion configured not to dissolve or swell in presence of said biomarker and methods of detecting presence of biomarkers in the vicinity of an implanted medical device.

A medical device includes a surgical needle, an elongated suture, and an intervening segment. The elongated suture has a first end proximate to the needle and a second end located away from the needle. The elongated suture also includes a plurality of fibers defining a mesh wall between the first and second ends. A plurality of pores extend through the mesh wall, at least some which are in the macroporous size range of greater than 200 microns for facilitating tissue integration when introduced into a body. The intervening segment is disposed between and connected to either or both ends of the elongated suture and the needle. The intervening segment includes one or more fibers of the plurality of fibers and has a cross-sectional dimension smaller than a cross-sectional dimension of the mesh wall such that the intervening segment facilitates indirect attachment of the elongated macroporous mesh suture to the needle.

The present application relates to fibers having a diameter of 1 nm to 10,000 nm, of one or more biocompatible polymers, wherein the polymers have a backbone which includes a positively charged component from a zwitterionic moiety. Additionally, this application discloses an implantable therapeutic delivery system and its method of formation, comprising a housing defining a chamber, wherein said housing is porous and formed from the fibers. Inside of the housing includes a preparation of cells which release a therapeutic agent from the chamber. The implantable therapeutic delivery system can be used in the treatment of diabetes.

A surgical suture includes an elongated core comprising a plurality of bundles of bio-composites of fibers made from Agave americana plant leaf. A surgical bio-suture material core from Agave americana plant fibers has two ends and one end combined with a surgical needle.