A material or biomaterial comprising silicic acid condensates having a low degree of cross-linking, and methods for its production are subject-matter of the invention. A method for the production of silicic acid structures having a low degree of cross-linking is disclosed, wherein a sol is produced, wherein further condensation is prevented when specific cross-linking of the silicic acid is reached, wherein, preferably, structures having a size of 0.5-1000 nm are produced, e.g. polyhedral structures or aggregates of the same. Further condensation can be prevented by means of mixing with a polymer. In one embodiment, this comprises nano-structured, silicon dioxide (SiO.sub.2) having a low degree of cross-linking that is embedded in a polymer matrix. The material can be used in medicine for therapeutic purposes, and can enter into direct contact with biological tissue of the body in this connection. This material herein enters into chemical, physical, and biological interactions with the corresponding biological systems. It can herein be decomposed, and can act as a supplier for the silicic acid required for metabolism. Furthermore, it can have a supportive or shielding effect. It can be present as a granulate, microparticles, fiber, and as a woven or nonwoven fabric produced therefrom, or as a layer on implants or wound dressings. The material can be used as a medical device or as a nutritional supplement.

The invention relates to a biodegradable graphene oxide biocomposite fibrous membrane and a preparation method and uses thereof. The composite fibrous membrane comprises biodegradable graphene oxide biocomposite fibers, each fiber has an outer layer consisting of graphene oxide-biodegradable polymer nanofibers and an inner layer consisting of sodium alginate/polyvinyl alcohol nanocomposite fibers. The biodegradable graphene oxide biocomposite fibrous membrane of the invention has the advantages of good biocompatibility, biodegradability, swellability, bacteriostasis and good mechanical properties and chemical stability.

The invention relates to a biodegradable graphene oxide biocomposite fibrous membrane and a preparation method and uses thereof. The composite fibrous membrane comprises biodegradable graphene oxide biocomposite fibers, each fiber has an outer layer consisting of graphene oxide-biodegradable polymer nanofibers and an inner layer consisting of sodium alginate/polyvinyl alcohol nanocomposite fibers. The biodegradable graphene oxide biocomposite fibrous membrane of the invention has the advantages of good biocompatibility, biodegradability, swellability, bacteriostasis and good mechanical properties and chemical stability.

A shape memory adhesive material for adhering and contracting wounds, particularly diabetic wounds, to facilitate their closure and healing. The shape memory adhesive is pre-stretched and dried to provide an adhesive structure with a pre-programmed strain, wherein the adhesive is capable of rapid robust adhesion followed by predictive contraction upon contact with a wet surface. According to preferred embodiments, the shape memory adhesive material includes a combination of one or more hydrophilic polymers or copolymers, one or more amine coupling group, and one or more cross linkers.

A composition has an enzyme that is able to convert a substrate to release hydrogen peroxide; a substrate for the enzyme; and a superabsorbent component, such as a superabsorbent polymer. The composition is in the form of a powder and may form a gel on contact with water.

A composition, comprising a hydrogel matrix and microparticles within said matrix, said matrix comprising a cross-linkable protein and a cross-linking agent, wherein said cross-linking agent is able to cross-link said cross-linkable protein, wherein said microparticles comprise a drug.

A composition, comprising a hydrogel matrix and microparticles within said matrix, said matrix comprising a cross-linkable protein and a cross-linking agent, wherein said cross-linking agent is able to cross-link said cross-linkable protein, wherein said microparticles comprise a drug.

A curable composition apportioned between at least one Part A and at least one Part B, the Parts sealed within barrier means preventing contamination, the at least one Part A comprising: (i) one or more alkenyl-group containing prepolymers having at least one alkenyl group or moiety per molecule, and the at least one Part B comprising: (ii) one or more SiH-containing prepolymers having at least one SiH unit per molecule; the composition additionally comprising: (iii) a catalyst for curing by addition of alkenyl-containing prepolymer (i) to SiH-containing prepolymer (ii), wherein prepolymer (ii) is substantially absent from Part A and prepolymer (i) is substantially absent from Part B, methods for preparing the composition, methods for sterilisation thereof, medical and non-medical use thereof, a device incorporating the composition, and a precursor therefor including its sterilisable precursor composition, in particular a terminally sterilisable or terminally sterile composition for medical use, particularly in wound therapy, more particularly as a wound packing material which can be shaped and configured to the shape of a wound, most particularly for application in negative pressure wound therapy (NPWT).

Described herein are compositions of collagen and micronized placental tissue components, methods for producing the same and methods for using the same for wound healing, repairing damaged tendons, cosmetic applications and covering biocompatible materials and/or devices.

The present invention belongs to the field of medical materials. A nano-oxide/kaolin composite hemostatic antibacterial material includes an iron oxide/kaolin composite carrier, and zinc oxide supported on the surface of the composite carrier. The present invention further provides the preparation and application of the composite hemostatic antibacterial material. Furthermore, the present invention provides a hemostatic healing-promoting dressing including the composite hemostatic antibacterial material disclosed by the present invention. The present invention surprisingly finds from research that the zinc oxide and iron oxide/kaolin composite carrier have a synergistic effect, and further cooperated with a special loading morphology, the synergistic effect of the two is unexpectedly enhanced, the hemostatic property and antibacterial property of the material are effectively improved, and moreover, the rate of wound healing is further improved.