The present invention relates to an elongate, flexible, medical device comprising: an elongate, flexible inner member; a support member extending around the inner member; a plurality of electrically-conductive wires, each being braided with the support member; an outer member; and at least one ionic electroactive polymer actuator, the actuator comprising: at least one polymer electrolyte layer secured adjacent to the distal end of the inner member; and a plurality of electrodes circumferentially distributed about the exterior surface of the at least one polymer electrolyte layer, wherein at least one of the plurality of electrically-conductive wires, adjacent to the distal end thereof, is electrically connected to one of the electrodes, and the at least one polymer electrolyte layer is configured to deform asymmetrically in response to the application of an electrical signal through at least one of the plurality of electrically-conductive wires to at least one of the plurality of electrodes.

A tube-containing medical device assembly or tube-containing medical device kit can include a tube-containing medical device including an access opening positionable exterior with respect to a subject, a fluid communication opening positionable within the subject to fluidically communicate with a body fluid of the subject, and an elongated lumen therebetween. A luminal wire is inserted or insertable in the elongated lumen, wherein the luminal wire has a length that is within or will be positioned with 5% to 100% of the elongated lumen. The luminal wire can have an x-y cross-sectional diameter sufficiently smaller than an x-y cross-sectional diameter of the elongated lumen to allow removal and/or insertion of the luminal wire (initially or as a replacement). The luminal wire in the present disclosure is bioactive.

A tube-containing medical device assembly or tube-containing medical device kit can include a tube-containing medical device including an access opening positionable exterior with respect to a subject, a fluid communication opening positionable within the subject to fluidically communicate with a body fluid of the subject, and an elongated lumen therebetween. A luminal wire is inserted or insertable in the elongated lumen, wherein the luminal wire has a length that is within or will be positioned with 5% to 100% of the elongated lumen. The luminal wire can have an x-y cross-sectional diameter sufficiently smaller than an x-y cross-sectional diameter of the elongated lumen to allow removal and/or insertion of the luminal wire (initially or as a replacement). The luminal wire in the present disclosure is bioactive.

Aspects of the invention relate to a metal material and article made from the metal material having biological properties, such as antibiotic properties.

An elongate body extending from a proximal end to a distal end includes a core comprising an amorphous metal alloy and includes a sheath that comprises a crystalline metallic material. The sheath surrounds the core.

An elongate body extending from a proximal end to a distal end includes a core comprising an amorphous metal alloy and includes a sheath that comprises a crystalline metallic material. The sheath surrounds the core.

The present invention relates to a perfusion balloon catheter that has an expandable (enlargeable) inner lumen with a novel design feature that allows a continuous flow through this enlarged lumen sufficient perfusion to the distal lumen of the blood vessel or air passage concurrent to and independently of balloon inflation or deflation resulting in the prolonged dilatation and avoiding the high risks of blood or air flow stricture during balloon inflation.

The present invention relates to a perfusion balloon catheter that has an expandable (enlargeable) inner lumen with a novel design feature that allows a continuous flow through this enlarged lumen sufficient perfusion to the distal lumen of the blood vessel or air passage concurrent to and independently of balloon inflation or deflation resulting in the prolonged dilatation and avoiding the high risks of blood or air flow stricture during balloon inflation.

The present invention relates to a method of preparing reduced graphene oxide, incorporation of the reduced graphene oxide into polyisoprene latex to provide a polyisoprene latex graphene composite and elastomeric articles prepared using the polyisoprene latex-graphene composite. In particular, the reduction of graphene oxide is accomplished without the use of strong reducing agents and organic solvents and incorporation of the reduced graphene oxide into polyisoprene latex is accomplished using room temperature latex mixing method or hot maturation. The resultant composite exhibits good colloid stability, and polyisoprene latex films produced the composite exhibit good mechanical properties with improved ageing resistance.

The present invention relates to a method of preparing reduced graphene oxide, incorporation of the reduced graphene oxide into polyisoprene latex to provide a polyisoprene latex graphene composite and elastomeric articles prepared using the polyisoprene latex-graphene composite. In particular, the reduction of graphene oxide is accomplished without the use of strong reducing agents and organic solvents and incorporation of the reduced graphene oxide into polyisoprene latex is accomplished using room temperature latex mixing method or hot maturation. The resultant composite exhibits good colloid stability, and polyisoprene latex films produced the composite exhibit good mechanical properties with improved ageing resistance.