Embodiments for a Mooreville Needle Introducer, and methods for using and making the same are disclosed. The Mooreville Needle Introducer can be constructed of a first part and a second part that can be joined together to form an enclosure for receiving a pusher. The first part and the second part can also be formed with pairs of complementing adapters that fasten together for secure alignment. The first part can be detached from the second part by applying force to a set of handles. When the first part and the second part are detached, they can be effectively cleansed and sterilized, eliminating any lingering bacteria.

A neurovascular catheter extension segment is provided, such as for distal neurovascular access or aspiration. The neurovascular catheter extension segment includes 1) an elongate flexible control wire having a proximal end and a distal end and 2) a tubular extension segment having a side wall defining a central lumen carried by the distal end of the control wire. The side wall of the tubular extension segment includes a tubular inner liner, a tie layer separated from the lumen by the inner liner, a helical coil surrounding the tie layer, and an outer jacket surrounding the helical coil. The extension segment may be introduced into the proximal end of a neurovascular catheter and advanced distally to extend beyond the catheter and thereby extend the reach of the catheter.

A medical device and a method and process for at least partially forming a medical device, which medical device has improved physical properties. The one or more improved physical properties of the novel metal alloy can be achieved in the medical device without having to increase the bulk, volume and/or weight of the medical device.

The present invention relates to a medical Au—Pt—Pd alloy including Au, Pt, Pd, and inevitable impurities. The alloy has an alloy composition inside a polygon (A1-A2-A3-A4-A5-A6) surrounded by straight lines connected at point A1 (Au: 37.9 atom %, Pt: 0.1 atom %, and Pd: 62 atom %), point A2 (Au: 79.9 atom %, Pt: 0.1 atom %, and Pd: 20 atom %), point A3 (Au: 79.9 atom %, Pt: 20 atom %, and Pd: 0.1 atom %), point A4 (Au: 69.9 atom %, Pt: 30 atom %, and Pd: 0.1 atom %), point A5 (Au: 49 atom %, Pt: 30 atom %, and Pd: 21 atom %), and point A6 (Au: 39 atom %, Pt: 40 atom %, and Pd: 21 atom %) in a Au—Pt—Pd ternary state diagram. The metal structure of the alloy is optimized, and the metal structure is close to a single-phase structure, and has little precipitation of a Au-rich phase and a Pt-rich phase different in composition from a mother phase.

An intravascular Doppler ultrasonic device comprises a tip region forming a fraction of a catheter body at a distal end thereof and carrying an ultrasound probe. The tip region is bendable in a direction perpendicular to a longitudinal direction. An actuator is provided in the tip region, which is configured to receive actuation drive power provided through the catheter body and to exert to the tip region a bending moment of a controllable amount. An actuation controller is configured to control actuation drive power delivery to the actuator so as to control the amount of the bending moment. A Doppler spectrum analysis unit is configured to receive Doppler spectrum data and to determine from it a Doppler signal quality measure indicative of a signal quality of the Doppler spectrum. The actuation controller is configured to determine the actuation drive power in dependence on the determined Doppler signal quality measure.

An intravascular Doppler ultrasonic device comprises a tip region forming a fraction of a catheter body at a distal end thereof and carrying an ultrasound probe. The tip region is bendable in a direction perpendicular to a longitudinal direction. An actuator is provided in the tip region, which is configured to receive actuation drive power provided through the catheter body and to exert to the tip region a bending moment of a controllable amount. An actuation controller is configured to control actuation drive power delivery to the actuator so as to control the amount of the bending moment. A Doppler spectrum analysis unit is configured to receive Doppler spectrum data and to determine from it a Doppler signal quality measure indicative of a signal quality of the Doppler spectrum. The actuation controller is configured to determine the actuation drive power in dependence on the determined Doppler signal quality measure.

A medical device includes a base layer, and a lubrication layer supported on at least a part of the base layer, wherein the lubrication layer contains a block copolymer (A) composed of a first constituting unit derived from a reactive monomer that has an epoxy group and a second constituting unit derived from at least one hydrophilic monomer selected from the group consisting of acrylamide and an acrylamide derivative, and a polymer (B) composed of a constituting unit derived from at least one hydrophilic monomer selected from the group consisting of acrylamide and an acrylamide derivative, wherein the block copolymer (A) is contained in a proportion of 20 to 80% by weight relative to the total weight of the block copolymer (A) and the polymer (B), and wherein the block copolymer (A) is crosslinked or polymerized to form a mesh structure.

A medical device includes a base layer, and a lubrication layer supported on at least a part of the base layer, wherein the lubrication layer contains a block copolymer (A) composed of a first constituting unit derived from a reactive monomer that has an epoxy group and a second constituting unit derived from at least one hydrophilic monomer selected from the group consisting of acrylamide and an acrylamide derivative, and a polymer (B) composed of a constituting unit derived from at least one hydrophilic monomer selected from the group consisting of acrylamide and an acrylamide derivative, wherein the block copolymer (A) is contained in a proportion of 20 to 80% by weight relative to the total weight of the block copolymer (A) and the polymer (B), and wherein the block copolymer (A) is crosslinked or polymerized to form a mesh structure.

Provided is a super elastic alloy for biological use having a high biocompatibility, good processability and super elasticity, said super elastic alloy being a super elastic zirconium alloy for biological use comprising 27-54 mol % inclusive of titanium, 5-9 mol % inclusive of niobium which is a β phase-stabilizing element capable of stabilizing the β phase of zirconium, and 1-4 mol % inclusive in total of tin and/or aluminum which are ω phase-suppressing elements capable of suppressing the ω phase of zirconium, with the balance consisting of zirconium and inevitable impurities.

Provided is a super elastic alloy for biological use having a high biocompatibility, good processability and super elasticity, said super elastic alloy being a super elastic zirconium alloy for biological use comprising 27-54 mol % inclusive of titanium, 5-9 mol % inclusive of niobium which is a β phase-stabilizing element capable of stabilizing the β phase of zirconium, and 1-4 mol % inclusive in total of tin and/or aluminum which are ω phase-suppressing elements capable of suppressing the ω phase of zirconium, with the balance consisting of zirconium and inevitable impurities.