Patent classifications
A61L29/02
Methods of manufacturing monophasic action potential mapping catheters
A method for manufacturing a distal portion of a mapping and/or ablation device with fewer components and manufacturing steps than are required for presently known devices. The method generally includes aligning one or more electrodes and electrode wires within a housing mold, overmolding a biocompatible material over the one or more wires and a portion of each of the one or more electrodes, creating a housing component that integrates a dome component and an insulation component. Alternatively, the method generally includes aligning one or more wires within a housing mold so that at least a portion of each wire protrudes from the mold, overmolding a biocompatible material over the one or more wires, thus creating a housing component that integrates a dome component and insulation component. The protruding wire portions are cleaved off and at least a portion of the housing component is coated with a layer of conductive material.
Methods of manufacturing monophasic action potential mapping catheters
A method for manufacturing a distal portion of a mapping and/or ablation device with fewer components and manufacturing steps than are required for presently known devices. The method generally includes aligning one or more electrodes and electrode wires within a housing mold, overmolding a biocompatible material over the one or more wires and a portion of each of the one or more electrodes, creating a housing component that integrates a dome component and an insulation component. Alternatively, the method generally includes aligning one or more wires within a housing mold so that at least a portion of each wire protrudes from the mold, overmolding a biocompatible material over the one or more wires, thus creating a housing component that integrates a dome component and insulation component. The protruding wire portions are cleaved off and at least a portion of the housing component is coated with a layer of conductive material.
Layered Tube for Improved Kink Resistance
A catheter shaft is produced by forming a first polymeric layer onto a flexible inner core while maintaining the inner core in a solid state, and solidifying the first polymeric layer, wherein the solidified first polymeric layer fails to bond with the inner core and is slidable thereon upon flexion of the shaft. A second polymeric layer may be formed over the first polymeric layer, and is slidable thereon when the shaft bends.
Layered Tube for Improved Kink Resistance
A catheter shaft is produced by forming a first polymeric layer onto a flexible inner core while maintaining the inner core in a solid state, and solidifying the first polymeric layer, wherein the solidified first polymeric layer fails to bond with the inner core and is slidable thereon upon flexion of the shaft. A second polymeric layer may be formed over the first polymeric layer, and is slidable thereon when the shaft bends.
METAL MATERIAL HAVING BIOLOGICAL PROPERTIES
Aspects of the invention relate to a metal material and product made from the metal material having biological properties, such as antibiotic properties.
MEDICAL DEVICES COMPRISING DETACHABLE BALLOONS AND METHODS OF MANUFACTURING AND USE
The present disclosure relates to medical devices comprising detachable balloons and catheter assemblies, wherein the detachable balloons are polymer balloons, metal balloons, polymer-coated metal balloons, and metalized polymer balloons. Various means of attachment and detachment of the balloons to the catheter assemblies are described. Kits and uses of systems having one or more medical devices, detachable balloons, and elongated or expandable bodies are also disclosed.
MEDICAL DEVICES COMPRISING DETACHABLE BALLOONS AND METHODS OF MANUFACTURING AND USE
The present disclosure relates to medical devices comprising detachable balloons and catheter assemblies, wherein the detachable balloons are polymer balloons, metal balloons, polymer-coated metal balloons, and metalized polymer balloons. Various means of attachment and detachment of the balloons to the catheter assemblies are described. Kits and uses of systems having one or more medical devices, detachable balloons, and elongated or expandable bodies are also disclosed.
Ureteral Catheter Structure
A ureteral catheter structure, comprising a catheter body (1). The catheter body (1) comprises a stepped braided tube (2), a bending tube (3), and a plastic catheter tip (14) which are spliced with each other. A first stainless steel outer tube (4) supports and connects the stepped braided tube (2) and the bending tube (3) at a splice therebetween, and a first PET heat-shrinkable film (5) is coated on the first stainless steel outer tube (4). A second stainless steel outer tube (6) supports and connects the bending tube (3) and the plastic catheter tip (14) at a position therebetween, and a second PET heat-shrinkable film (7) is coated on the second stainless steel outer tube (6). A traction wire (8) is provided within the catheter body (1), an end of the traction wire (8) being fixed on the bending tube (3), while the other end passing through the stepped braided tube (2). A heat-shrinkable sleeve (9) is provided outside the bending tube (3). An end of the ureteral catheter may be independently bent in multiple sections, thereby achieving a good detection effect, and solving the technical problem of instability when an end of the ureteral catheter is deflected.
Ureteral Catheter Structure
A ureteral catheter structure, comprising a catheter body (1). The catheter body (1) comprises a stepped braided tube (2), a bending tube (3), and a plastic catheter tip (14) which are spliced with each other. A first stainless steel outer tube (4) supports and connects the stepped braided tube (2) and the bending tube (3) at a splice therebetween, and a first PET heat-shrinkable film (5) is coated on the first stainless steel outer tube (4). A second stainless steel outer tube (6) supports and connects the bending tube (3) and the plastic catheter tip (14) at a position therebetween, and a second PET heat-shrinkable film (7) is coated on the second stainless steel outer tube (6). A traction wire (8) is provided within the catheter body (1), an end of the traction wire (8) being fixed on the bending tube (3), while the other end passing through the stepped braided tube (2). A heat-shrinkable sleeve (9) is provided outside the bending tube (3). An end of the ureteral catheter may be independently bent in multiple sections, thereby achieving a good detection effect, and solving the technical problem of instability when an end of the ureteral catheter is deflected.
Synergistic antibacterial activity of medium polarity oils in combination with antibacterial agents on bacterial biofilms
The compositions of the present invention comprise at least one medium polarity oil and at least one antibacterial agent, the combination of which produces a synergistic antibacterial effect against bacterial biofilms. Methods are disclosed for the reduction of bacteria in and/or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms.