Reinforcing sleeves for medical device lumens are disclosed. In some embodiments reinforcing sleeves may provide resistance to crushing, kinking, or other deformation of the lumen. Reinforcing sleeves within the scope of this disclosure may be displaceable along an outer diameter of a reinforced lumen. Some reinforcing sleeves within the scope of this disclosure comprise metal alloys.

There is provided a method for decreasing leakage of matter from an object to a surrounding, said object being coated with a coating at least partially applied on the object, said coating comprising an at least partially covering layer comprising silver, said object optionally comprising area(s) without said layer, said coating comprising metal particles applied on the layer and optionally on areas without said layer, said metal particles comprising palladium and at least one metal selected from the group consisting of gold, ruthenium, rhodium, osmium, iridium, niobium, neodymium and platinum and wherein the amount of the metal particles is in the interval 0.01-8 μg/cm.sup.2. Advantages include that leakage of matter such as latex allergens of metal ions can be reduced while the coating is both biocompatible and antimicrobial. Further, the blood clotting can be reduced.

Medical tube can have a continuous inner layer having a continuous outer layer thereon, in which the inner layer includes a polyolefin such as a polyethylene or polypropylene or a functionalized polyolefin. The outer layer can include a thermoplastic polymer such as one or more of, or a blend including, a thermoplastic polyurethane (TPU), a thermoplastic olefin (TPO), a thermoplastic elastomer (TPE), a styrene-containing thermoplastic elastomer (S-TPE), a polyolefin elastomer (POE), a styrenic blocking copolymer (SBC). Advantageously, the outer layer and/or the inner layer do not include polyvinyl chloride. Such tubing can be used as medical device such as with infusion sets.

High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces. Polymers may be entrapped in pores of materials to provide a durable modification of the materials.

An insertion set system includes a base configured to be secured to a patient, and a flexible tubing on the base. The flexible tubing has a distal end portion forming a cannula to be inserted into the patient. An inserter having a needle is received by the base. The needle has a channel in which the distal end portion of the flexible tubing is received. The needle is able to slide relative to the flexible tubing, to selectively withdraw the needle off of the distal end portion of the flexible tubing. The base may include a passage for fluid flow arranged transverse to the axial dimension of the distal end portion of the flexible tubing.

This application provides methods, compositions, and kits for use in removing kinks in tubing.

The elastomer composition of the present invention comprises a thermoplastic elastomer composition which contains 20 to 80% by weight of component (A), 1 to 25% by weight of component (B), and 1 to 70% by weight of component (C): Component (A): at least one block copolymer selected from: a block copolymer having a polymer block derived from a vinyl aromatic compound and a polymer block derived from at least one selected from a conjugated diene and isobutylene; and a block copolymer obtained by hydrogenating the block copolymer; Component (B): a polypropylene resin containing component (B1): a modified polypropylene obtained by graft-modifying a polypropylene resin with a diene compound; and Component (C): a hydrocarbon softener for rubber.

The elastomer composition of the present invention comprises a thermoplastic elastomer composition which contains 20 to 80% by weight of component (A), 1 to 25% by weight of component (B), and 1 to 70% by weight of component (C): Component (A): at least one block copolymer selected from: a block copolymer having a polymer block derived from a vinyl aromatic compound and a polymer block derived from at least one selected from a conjugated diene and isobutylene; and a block copolymer obtained by hydrogenating the block copolymer; Component (B): a polypropylene resin containing component (B1): a modified polypropylene obtained by graft-modifying a polypropylene resin with a diene compound; and Component (C): a hydrocarbon softener for rubber.

An implantable device and methods for preparing and implanting said device into a subject for use in treating a medical condition when implanted therein is disclosed. The device comprises at least one coaxial fibre of a hydrophilic polymer and a hydrophobic polymer, wherein at least one of said polymers is loaded with an agent that is active towards treating the medical condition.

The invention is directed to an ion plasma deposition (IPD) method adapted to coat polymer surfaces with highly adherent antimicrobial films. A controlled ion plasma deposition (IPD) process is used to coat a metal or polymer with a selected metal/metal oxide. Exposing the coated surface to ultraviolet light significantly improves the antimicrobial properties of the deposited coatings.