A delivery device suitable for delivering a chemical substance, e.g. a medical device such as a catheter, a microcapsule, an implantable capsule or a P-ring, or a delivery device for use in the construction industries e.g. in the form of microcapsules comprising antifouling agent for marine paint. The delivery device includes a closed cavity, the cavity is defined by an innermost wall surface, wherein at least a section of the inner wall surface constitutes an inner surface of a delivery membrane wherein the delivery membrane includes an interpenetrating polymer network substrate comprising a host polymer and a guest polymer, where the guest polymer is interpenetrating the host polymer to form substantially continuous pathways within said host polymer.

Inserts can be formed with elution characteristics to cause the inserts to elute an antimicrobial agent when subject to a fluid within a medical device. An insert can be formed with a desired geometry to allow the insert to be compression fit within a medical device to prevent the insert from moving or becoming dislodged once inserted into the medical device. The material may also be hygroscopic so that the insert swells when subject to a fluid thereby enhancing the compression fit of the device within the medical device. In some cases, the material can be reinforced using an internal structure. Inserts can be formed in many ways including by casting, thermoforming, or extrusion. In some cases, the inserts can be formed using a peel-away sleeve or material. The peel-away sleeves can be formed of a non-sticky material which facilitates removal of the inserts once the inserts have cured.

A method for manufacturing a functional elongate instrument includes: a base material preparation step of obtaining a wire-inserted base material by inserting a first wire as an actuator member through a first through-hole of a plurality of through-holes formed in a base material and inserting a second wire opposite to the first wire through a second through-hole of the plurality of through-holes; a composite fiber formation step of obtaining a composite fiber by heating and drawing the wire-inserted base material while supplying the first wire and the second wire; a connection step of forming, at a tip portion of the composite fiber, a connection portion configured to electrically connect the first wire and the second wire; and an insulation step of forming an insulating layer on a surface of the connection portion.

High strength biomedical materials and processes for making the same are disclosed. Included in the disclosure are nanoporous hydrophilic solids that can be extruded with a high aspect ratio to make high strength medical catheters and other devices with lubricious and biocompatible surfaces. Polymers may be entrapped in pores of materials to provide a durable modification of the materials.

An ultrasonic endoscope includes: a distal end part which includes an ultrasound transmission and reception section and an imaging unit, the ultrasound transmission and reception section includes an ultrasonic oscillator and a backing material layer, and a glass transition temperature of the backing material layer is 45 degrees or lower.

The present invention provides a method of manufacturing a medical device including a substrate and a hydrophilic polymer layer, including the steps of: placing the substrate in a solution containing a hydrophilic polymer and a normal salt in an amount ranging from 1.0 to 20% by mass; and heating the solution at a temperature ranging from 50 C. to 140 C. The present invention provides a simple method of manufacturing a medical device having excellent durability and imparted with hydrophilicity.

The present invention provides a method of manufacturing a medical device including a substrate and a hydrophilic polymer layer, including the steps of: placing the substrate in a solution containing a hydrophilic polymer and a normal salt in an amount ranging from 1.0 to 20% by mass; and heating the solution at a temperature ranging from 50 C. to 140 C. The present invention provides a simple method of manufacturing a medical device having excellent durability and imparted with hydrophilicity.

A medical device includes a mottled structure containing silicone and an antibacterial agent at a surface of the medical device.

The present disclosure relates to a self-lubricating cannula for use in delivering a fluid medication to a subcutaneous site. The self-lubricating cannula comprises polyether block polyamide and an additive configured to facilitate the manufacture of a tipped self-lubricating cannula. The present disclosure also provides a method of making a self-lubricating cannula and a method of administering insulin using a self-lubricating cannula.

Disclosed is a catheter tubing having surface expression of organo-selenium compositions capable of presenting anti-microbial properties on the surface of the catheter tubing which prevent microbial growth and the formation of biofilms. The disclosed compositions and methods support a wide variety of scenarios for catheter tubing applications, as organo-selenium can be stably incorporated into catheter tubing to inhibit bacterial attachment, growth, and biofilm formation for multiple uropathogenic organisms for long-term use with minimal to no leaching.