A process for coating parylene onto a metal surface, such as a medical device, that has been textured by a series of laser pulses. The laser pulses can be overlapping or rastered. The textured portion of the metal surface and parylene coating can form a strong mechanical interlock. The bond created by using the laser texturing process can result in a cohesive failure of the parylene and not an adhesive failure of the bonding.

An endovascular apparatus, including an elongated catheter having an inner lumen extending therethrough; a balloon affixed to the catheter for expansion into the inner lumen of the catheter when the balloon is inflated; and a tube secured relative to the balloon, wherein the tube is configured to enable selective inflation and deflation of the balloon, and wherein an outer diameter of a portion of the catheter adjacent the balloon is substantially the same when the balloon is inflated and when the balloon is deflated.

Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The medical device can include a composite cover formed of a deposited metallic film. The cover may include one or more filaments, e.g., wires, which cooperate with the film to provide desirable mechanical properties. The wires may be integrated with the film by depositing the film over the wires.

A vascular implant, comprising a sheet comprising thin film nickel titanium (NiTi), wherein the sheet has at least one super-hydrophilic surface having a water contact angle of less than approximately 5 degrees. The sheet is configured to have a compacted form having a first internal diameter and a deployed form having a second internal diameter larger than the first internal diameter. The sheet may be delivered into a blood vessel in the compacted form and expanded to its deployed form at a treatment location within the blood vessel, wherein the stent is configured to expand onto an internal surface of the blood vessel and exert a radial force on said internal surface.

An implant comprises a substrate and a coating on a surface of the substrate, and the coating comprises silicon nitride and has a thickness of from about 1 to about 15 micrometer. A method of providing the implant comprises coating a surface of the implant substrate with the coating comprising silicon nitride and having a thickness of from about 1 to about 15 micrometer by physical vapour deposition.

The invention relates to endovascular medical implant devices and materials of composition for forming these devices to provide improved mechanical properties and biodegradability. The devices include a combination or integration of superelastic material, biodegradable metal and, thin film nitinol and/or biodegradable polymer. A structural frame is formed of individual elongated pieces composed of biodegradable metal. These pieces are joined together by connector pieces composed of superelastic material. At least a portion of the structural frame has deposited thereon the thin film nitinol and/or biodegradable polymer. The structural frame of the device is collapsible for insertion in a delivery tube and, recoverable for deployment and placement in a vascular location of a patient body.

A degradable iron-based alloy stem comprises an iron-based alloy substrate and a degradable polymer in contact with the surface of the substrate. The weight-average molecular weight of the degradable polymer is in the range of [1, 100]*10.sup.4, and the polydispersity index of the degradable polymer is in the range of (1.0. 50]. The degradable polymer is selected from a degradable polyamino acid that can generate an acidic amino acid after degradation; or a mixture of the degradable polyamino acid and a degradable polyester, or a copolymer of monomers of the two; or a mixture of the degradable polyamino acid and a degradable polymer that does not generate acidic products after degradation, or a copolymer of the monomers of the two; or a mixture of the degradable polyamino acid, the degradable polyester and the degradable polymer that does not generate acidic products after degradation, or a copolymer of monomers of the three, or a mixture of a copolymer of monomers of any two of the three with the remaining one.

A degradable iron-based alloy stem comprises an iron-based alloy substrate and a degradable polymer in contact with the surface of the substrate. The weight-average molecular weight of the degradable polymer is in the range of [1, 100]*10.sup.4, and the polydispersity index of the degradable polymer is in the range of (1.0. 50]. The degradable polymer is selected from a degradable polyamino acid that can generate an acidic amino acid after degradation; or a mixture of the degradable polyamino acid and a degradable polyester, or a copolymer of monomers of the two; or a mixture of the degradable polyamino acid and a degradable polymer that does not generate acidic products after degradation, or a copolymer of the monomers of the two; or a mixture of the degradable polyamino acid, the degradable polyester and the degradable polymer that does not generate acidic products after degradation, or a copolymer of monomers of the three, or a mixture of a copolymer of monomers of any two of the three with the remaining one.

Ophthalmic devices having elastic electrodes are disclosed herein. An example ophthalmic device may be an intraocular lens that includes a support structure, two optical windows, two immiscible fluids, and an elastic electrode. The support structure may have an inner surface defining an aperture with first and second optical windows disposed on opposite sides of the support structure and spanning the aperture. The two immiscible liquids may be disposed in a cavity formed by the aperture and the first and second optical windows, and the elastic electrode may be disposed on the inner surface. The elastic electrode may be formed from an elastic metal alloy having a minimum yield strain of 0.25%.

A medical device and a method and process for at least partially forming a medical device, which medical device has improved physical properties.