Disclosed is a medical instrument coating, being coated on the surface of a nickel-titanium alloy component of a medical instrument. The medical instrument coating comprises an elementary copper phase, an amorphous titanium-containing substance and a transition layer comprising a copper-nickel intermetallic phase. Also mentioned is a preparation method for the medical instrument coating. A medical instrument comprising a copper-titanium coating has good blood compatibility, and simultaneously can inhibit the endothelialization of the medical instrument surface, thereby improving the recovery rate of the medical instrument and prolonging the recovery time window; the copper-titanium coating belongs to the group of metal composite coatings, has a certain toughness and ductility, and avoids the large-amplitude deformation process of the medical instrument damaging the coating; and the mechanical property and the coating quality of the medical instrument comprising a fine nickel-titanium alloy component are guaranteed by the method for preparing the coating.

A medical material uses a nickel-titanium alloy wherein a polyelectrolyte has a reduced thickness while a sufficient amount of an antithrombogenic compound for production of a therapeutic effect is supported. The medical material in which a porous surface is formed on a nickel-titanium alloy to allow infiltration of a polyelectrolyte into the pores, to thereby reduce the thickness of the polyelectrolyte exposed on the surface of the nickel-titanium alloy while allowing supporting of a sufficient amount of an antithrombogenic compound due to contribution of the polyelectrolyte infiltrate.

A medical device and a method and process for at least partially forming a medical device, which medical device has improved physical properties.

An improved abdominal hernia repair system is presented comprised of a silicone layer backed up with a knitted or woven polypropylene fabric layer, the silicone layer possessing a regular pattern of slits that permit equilibration of fluid pressure across the device. A variety of therapeutic substances can be applied to the hernia repair device to promote healing, including aloe and other medicinal preparations. A layer of water soluble or water insoluble anti-scar compound is also present, the preferred compound being Salinomycin.

An improved inguinal hernia repair system is presented that is identical to the above except it does not contain the hydrophobic silicone component.

Provided herein is a drug delivery system comprising: a. substrate; b. a plurality of components combined with the substrate to form the drug delivery system; wherein at least one components comprises a bioabsorbable polymer and at least one other component comprises one or more active agents; wherein at least part of the active agent is in crystalline form.

The invention relates to a magnesium alloy containing (in % by weight) more than 0.0 to 7.0% zinc, optionally more than 0.0 to 1.0% zirconium, optionally more than 0.0 to 1.0% calcium, optionally more than 0.0 to 1.0% manganese, optionally more than 0.0 to 0.5% silicon, optionally more than 0.0 to 1.0% silver, a max. up to 0.5% aluminum and at least one element selected from the group comprising more than 0.05 to 0.6% yttrium, more than 0.05 to 4.0% ytterbium, more than 0.05 to 4.0% gadolinium, with the residue being magnesium and impurities due to production. The invention also relates to a use of a magnesium alloy of this type and an implant therefrom and a method for producing a body of a magnesium alloy according to the invention.

A vertebral fixation device and corresponding method of fixation hold a spinal vertebra on a rod. The device has a fixation element including a component of substantially U-shaped cross section with a first branch, a bottom and a second branch. A loop is formed by a flexible band for connecting the vertebra to the component, and which passes through recesses provided in the branches. Adjustable means for immobilizing the flexible band are provided. Those means include a connector screw having a head for longitudinal immobilization of the screw with respect to the first branch a thread for screwing in the second branch. A removable sleeve for passage of the screw, insertable in the first branch, in longitudinal abutment with the head of the screw is provided and presents a chamfered part designed to cooperate with the rod to compress the band between the rod and the bottom of the component.

A magnetic article with a corrosion resistant barrier formed from a poly(tetrafluoro-p-xylene) conformal coating or from a parylene conformal coating having a melting point of at least about 430° C. and a moisture vapor transmission less than about 0.5 g-mm/m.sup.2/day at 90% RH and 37° C., the conformal coating being covered with a polysulfone thermoplastic overlayer.

An electrode for use with an implantable medical device includes an alloy and a conductive oxide layer on a surface of the alloy. The alloy includes iridium and at least one of cobalt and iron. The conductive oxide layer includes iridium oxide. The conductive oxide layer has a thickness greater than about 5 nanometers.

A near net shape medical device is described that is formed from a metal alloy mixture containing NiTiHf using additive manufacturing techniques. The medical device is aged to a desired ultimate tensile strength (UTS), presence of H-phase precipitate with an A.sub.f below body temperature.