A method for occluding a blood vessel has steps for encasing a semi-rigid, circular plastic ring, open at one point, in silicon material, forming a bladder along an inside diameter of the silicon material, placing a mixture of sodium and potassium salts and polyacrylamide granules in the bladder, closing and sealing the bladder, forming a pair of opposed stirrups on an outside diameter of the silicon material, spreading the encased plastic ring by the stirrups accomplishing an opening through the ring of an extent enabling the ring to be placed over a blood vessel, placing the encased plastic ring over the blood vessel, releasing the stirrup, allowing the ring and bladder to close around the blood vessel, such that the bladder, constrained by the ring from expanding outward, absorbing moisture by osmosis over time, expands inward, and over a time t fully occludes the blood vessel.

Manufacturing an expandable body of a clot retrieval device having a first coating of radiopaque material defining a plurality of micro-columns and a second coating, the method including applying the first coating to strut elements, removing at least a portion of the first coating from at least one area of the strut elements, and cutting away regions of both the first coating and the strut elements to form an interconnected pattern of coated and uncoated regions.

Disclosed herein is a biomaterial and a method of use thereof for treating a condition. A biomaterial of the disclosure can be, for example, a surgical article. Implantation of a biomaterial disclosed herein into a subject can treat, for example, cancer.

A biosorbable magnetisable endoprosthesis, may be useful in the therapy of restenosis. A method for the treatment of prevention of restenosis or a disease of the coronary artery, comprises fitting a patent with an endoprosthesis according to the invention, which has either been magnetized prior to placement in the body or which is magnetized in situ, and administering to the patient magnetized cells capable of repairing an artery.

A method of modifying a surface of a medical device for implantation or disposition inside a patient is described. The medical device comprises a structure having at least one surface. The method includes the steps of: placing the medical device into a plasma chamber substantially free from contaminants and substantially sealing the plasma chamber from the atmosphere; removing at least an outermost layer of any oxide layer from the at least one surface of the structure by a plasma oxide-removal process, whilst maintaining the plasma chamber under seal from the atmosphere; and subsequently forming a new oxide layer at the least one surface of the structure by introducing at least one gas into the plasma chamber, whilst maintaining the plasma chamber under seal from the atmosphere. A medical device including a bulk material and an oxide layer disposed over at least one surface of the medical device. The oxide layer is substantially pure and free from contaminants.

The invention relates to compositions including magnesium-lithium alloys containing various alloying elements suitable for medical implant devices. The devices may be constructed of the compositions or have applied thereto a coating formed therefrom. Within the structure of the magnesium-lithium alloy, there is a co-existence of alpha and beta phases. The invention also relates to methods of preparing the magnesium-lithium alloys and articles, such as medical implant devices, for use in medical applications, such as but not limited to, orthopedic, dental, craniofacial and cardiovascular surgery.

The purpose of the present invention is to provide a viscoelastic composition having excellent operability, which is suitable for use in securing the field of view of an endoscope when opaque dark-colored liquid accumulates inside a canal and obstructs the field of view of the endoscope, the viscoelastic composition securing the field of view by pushing the liquid aside, and to provide a method for securing the field of view of an endoscope using the viscoelastic composition. The viscoelastic composition for securing the field of view of an endoscope comprises a substance having viscoelastic properties and water, preferably has a hardness of 550 N/m.sup.2 or less, a viscosity (25° C.) of 200 to 2,000 mPa.Math.s, and a loss tangent of 0.6 or less, and more preferably has an electrical conductivity of 250 μS/cm or less. The method for securing the field of view of an endoscope comprises feeding the viscoelastic composition from a proximal part of the endoscope, through a channel, into a distal part of the endoscope.

Systems, devices, and methods are provided for attaching and supporting a bone suture. In particular, described herein are embodiments of implantable bracing apparatuses comprising one or more curved tubes configured to be implanted in one or more bone tunnels, and further configured to pass one or more sutures therethrough. Embodiments of methods of creating a bracing apparatus in situ by injecting a fluidic agent into a bone tunnel and inducing a phase transition are also described. Furthermore, described herein are embodiments of tunneling devices for creating a bone tunnel, which can be used with any of the bracing apparatuses described herein.

Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.

Anatomically accurate brain phantoms are disclosed which may be patient specific and used for experimentally testing neuromodulation and neuroimaging procedures.