A61L31/08

Implantable chemical sensor with staged activation
11571151 · 2023-02-07 · ·

Embodiments herein include implantable medical devices including chemical sensors with bioerodible masking layers to allow for staged activation of the sensors. In an embodiment, an implantable medical device includes a substrate defining wells and a first chemical sensor and a second chemical sensor disposed within separate wells of the substrate. The first chemical sensor and the second chemical sensor can be configured to detect one or more analytes. The device can include a first bioerodible masking layer disposed over the second chemical sensor, sealing off the second chemical sensor. The device can further include a protective planarization layer disposed over at least one of the first chemical sensor and the second chemical sensor such that the outermost surface of the medical device over the first sensor is flush with the outermost surface of the medical device over the second sensor. Other embodiments are also included herein.

Endovascular Prostheses
20220347356 · 2022-11-03 ·

Low profile, self-expanding endovascular prostheses having a Ni-Ti alloy stent structure that is particularly well-suited for accessing and traversing narrow anatomical passageways and providing physiologically acceptable radial or hoop strength and longitudinal flexibility.

Endovascular Prostheses
20220347356 · 2022-11-03 ·

Low profile, self-expanding endovascular prostheses having a Ni-Ti alloy stent structure that is particularly well-suited for accessing and traversing narrow anatomical passageways and providing physiologically acceptable radial or hoop strength and longitudinal flexibility.

COATINGS FOR TREATMENT DEVICE
20220347357 · 2022-11-03 · ·

A treatment device equipped with high frequency capability includes a pair of clasping jaws that serves as bipolar electrodes. Another treatment device equipped with high frequency capability includes a high-frequency knife that serves as monopolar electrode. An anti-fouling coating that minimizes or prevents adhesion of cauterized tissues is incorporated on the electrode surfaces. Durability and functioning of the anti-fouling coating is improved by one or a combination of increased coating thickness, increased density of the coating, and incorporation of glass and/or high molecular weight PFPE into the coating. The anti-fouling coating can be applied to different locations of the treatment portion, e.g., an insulated portion and a recess of an electrode, an insulated portion and a boundary portion with an electrode.

CERIUM OXIDE NANOPARTICLE, DISPERSION BODY, OXIDANT, ANTIOXIDANT, AND METHOD OF PRODUCING CERIUM OXIDE NANOPARTICLE
20230030648 · 2023-02-02 ·

A cerium oxide nanoparticle is produced by mixing a solution of an aromatic heterocyclic compound having no substituent or at least one substituent selected from the group consisting of a methyl group, an ethyl group, an amino group, an aminomethyl group, a monomethylamino group, a dimethylamino group, and a cyano group and containing 2 to 8 carbon atoms and 1 to 4 nitrogen atoms in a ring structure of the aromatic heterocyclic compound, with a solution containing a cerium (III) ion or with a cerium (III) salt, followed by addition of an oxidant.

PHARMACEUTICAL PACKAGE FOR OPHTHALMIC FORMULATIONS

A liquid formulation of an ophthalmic drug in a pharmaceutical package, for example a syringe, cartridge, or vial, made in part or in whole of a thermoplastic polymer, coated on the interior with a tie coating or layer, a barrier coating or layer, a pH protective coating or layer, and optionally a lubricity coating or layer.

Tattoo needle structure

A tattoo needle structure is provided. A tattoo needle has a plurality of needle tips, an ink holding space is formed by the arrangement of the needle tips, and a multi-component alloy film is deposited on each needle tip of the tattoo needle by sputtering technology, so that when the tattoo needle is dipped into the tattoo ink, the tattoo ink does not stick to the surface of the multi-component alloy film by the hydrophobic property of the multi-component alloy film, and the tattoo ink is contained in the ink holding space by the cohesive property of the tattoo ink. Thus, when the tattoo needle is dipped into the tattoo ink and the tattoo process is performed, the dyeing area of the skin with the tattoo ink is the cross-sectional area of the ink holding space, thereby achieving the technical effect of improving the contouring resolution of a tattoo.

Implant for covering bone defects in the jaw region and method for producing the same

The invention relates to an implant for covering bone defects in the jaw region, which comprises a magnesium film.

Medical device
11471569 · 2022-10-18 · ·

The disclosed medical device has high visibility on non-woven fabric having a color such as green, blue, or the like, excellent identifiability from other medical devices having colors such as green, blue, or the like, and also a high adhesion property and strength of a coating. The medical device comprises an elongated body and a resin layer covering at least a proximal portion of the elongated body. The resin layer is comprised of a first layer which includes a first fluororesin, an organic pigment and titanium oxide, and a second layer which is formed on the first layer and includes a second fluororesin.

Biofilm resistant medical implant

A method of incorporating silver and/or copper into a biomedical implant includes: providing an implant having an outer surface; depositing silver and/or copper onto the outer surface of the implant; diffusing the silver and/or copper into a subsurface zone adjacent the outer surface; and oxidizing or anodizing the implant after the diffusion step to form an oxidized or anodized layer that contains at least some amount of elemental silver, elemental copper or silver or copper ions or compounds.