A coating agent can be applied to various materials without using radiation, and a medical material using the same. The coating agent containing a copolymer that contains: a monomer unit (unit A) containing a Si—O bond; a vinyl carboxylate monomer unit (unit B); and a monomer unit (unit C) containing a hydrophilic group.

The present disclosure provides synthetic collagen and methods of making and using synthetic collagen that include a synthetic collagen that facilitates wound closure comprising an isolated and purified triple helical backbone protein that facilitates wound closure comprising one or more alteration in a triple helical backbone protein sequence, that stabilize the isolated and purified triple helical backbone protein and does not disrupt an additional collagen ligand interaction; and one or more integrin binding motifs, wherein the isolated and purified triple helical backbone protein facilitates wound closure.

The present invention provides a coated article, which can be used in in-vitro diagnostics, in particular in the diagnostic testing of body fluids, such as in blood coagulation testing. The coated article is made of a polymer material and coated with a polymer material, which may be the same or different. The present invention furthermore provides a method of preparing such a coated article and a method of performing such diagnostics, e.g. coagulation analysis.

The present invention provides a coated article, which can be used in in-vitro diagnostics, in particular in the diagnostic testing of body fluids, such as in blood coagulation testing. The coated article is made of a polymer material and coated with a polymer material, which may be the same or different. The present invention furthermore provides a method of preparing such a coated article and a method of performing such diagnostics, e.g. coagulation analysis.

The present invention provides a coated article, which can be used in in-vitro diagnostics, in particular in the diagnostic testing of body fluids, such as in blood coagulation testing. The coated article is made of a polymer material and coated with a polymer material, which may be the same or different. The present invention furthermore provides a method of preparing such a coated article and a method of performing such diagnostics, e.g. coagulation analysis.

The present invention provides a coated article, which can be used in in-vitro diagnostics, in particular in the diagnostic testing of body fluids, such as in blood coagulation testing. The coated article is made of a polymer material and coated with a polymer material, which may be the same or different. The present invention furthermore provides a method of preparing such a coated article and a method of performing such diagnostics, e.g. coagulation analysis.

The present invention provides a coated article, which can be used in in-vitro diagnostics, in particular in the diagnostic testing of body fluids, such as in blood coagulation testing. The coated article is made of a polymer material and coated with a polymer material, which may be the same or different. The present invention furthermore provides a method of preparing such a coated article and a method of performing such diagnostics, e.g. coagulation analysis.

The present invention provides a coated article, which can be used in in-vitro diagnostics, in particular in the diagnostic testing of body fluids, such as in blood coagulation testing. The coated article is made of a polymer material and coated with a polymer material, which may be the same or different. The present invention furthermore provides a method of preparing such a coated article and a method of performing such diagnostics, e.g. coagulation analysis.

An example medical device includes a vascular device, such as a catheter, and an anti-thrombogenic coating on a surface of the vascular device, such as a surface likely to contact blood. The anti-thrombogenic coating includes one or more peptides configured to interact with fibrinogen in the blood, such as a first type of peptides configured to bind to fibrinogen a second type of peptides configured to inhibit conversion of fibrinogen to fibrin. The anti-thrombogenic coating also includes a polymer, such as a hydrocolloid polymer, a tunable polyethylene glycol (PEG), or other controlled release polymer configured to control release of the one or more peptides and maintain a concentration of the peptides at the surface of the anti-thrombogenic coating above a minimum inhibitory concentration, thereby inhibiting thrombin formation on the intravascular medical device.

An example medical device includes a vascular device, such as a catheter, and an anti-thrombogenic coating on a surface of the vascular device, such as a surface likely to contact blood. The anti-thrombogenic coating includes one or more peptides configured to interact with fibrinogen in the blood, such as a first type of peptides configured to bind to fibrinogen a second type of peptides configured to inhibit conversion of fibrinogen to fibrin. The anti-thrombogenic coating also includes a polymer, such as a hydrocolloid polymer, a tunable polyethylene glycol (PEG), or other controlled release polymer configured to control release of the one or more peptides and maintain a concentration of the peptides at the surface of the anti-thrombogenic coating above a minimum inhibitory concentration, thereby inhibiting thrombin formation on the intravascular medical device.