Disclosed are various bioactive and/or biocompatible materials and methods of making the same.

A medical device and methods for altering lung volume are disclosed. The medical device includes a coil formed of a biodegradable material including a first bioabsorbable material that is configured to deactivate a portion of a lung as the coil degrades. The method includes positioning a first coil adjacent a first target within a patient and permitting the first coil to degenerate such that a first bioabsorbable material deactivates a first portion of a lung. The first coil is formed of a biodegradable material and includes the first bioabsorbable material.

This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.

The subject invention is directed to devices and methods for producing devices for regulating blood flow in the venous system. In particular, the invention provides for artificial valves designed to regulate the flow of blood in human vessels, wherein such artificial valves include superior properties including fatigue resistance, biocompatibility, and ease of manufacture.

Disclosed are liquid cast biodegradable arterial stents and methods for preparing liquid cast biodegradable arterial stents. The typically includes a biodegradable polymer and may include an agent for treating neointimal hyperplasia.

The present description relates to the discovery of materials, devices, systems and methods for microfabrication of engineered tissue scaffolds for the growth and culture of biological tissues for tissue repair, transplantation, disease treatment, regenerative medicine, drug testing or combinations thereof. The engineered tissue scaffolds mimic native conditions and structures, including, e.g., native physiology, tissue architecture, vasculature, and other properties of native tissues.

Medical devices utilizing shape memory alloys and associated methods are disclosed herein. One aspect of the present technology, for example, is directed toward a treatment element configured to be positioned within a body lumen and coupled to an energy source. At least a portion of the treatment element may be made of a shape memory alloy, and wherein application of thermal energy to the treatment element from the energy source transforms the treatment element from the martensitic state to the austenitic state in which the treatment element is configured to cut, ablate, resect, and/or cauterize tissue.

Injectable bone graft material having a biocompatible, resorbable polymer and a biocompatible, resorbable inorganic material exhibiting macro, meso, and microporosities.

This invention relates to shape memory block copolymers comprising: at least one switching segment having a T.sub.trans from 10 to 70° C.; and at least one soft segment, wherein at least one of the switching segments in linked to at least one of the soft segments by at least one linkage, and wherein the copolymer transforms from a first shape to a second shape by application of a first stimulus and the copolymer transforms back to the first shape from the second shape by application of a second stimulus. The shape memory block copolymers may be biocompatible and biodegradable.

Radiopaque polymer compositions and methods for making the compositions are provided. These radiopaque polymer compositions include polymer compositions comprising a crosslinked polymer network, the network comprising a first repeating unit derived from a monofunctional monomer and a second repeating unit derived from a multifunctional non-iodinated monomer wherein neither of the two monomers is fluorinated. Devices formed from radiopaque polymer compositions are also provided.