A coated urinary catheter or urinary stent device includes a urinary catheter or stent which, in a deployed position, includes or defines a protective surface area and a protected surface area and a coating upon at least a portion of the protective surface area. The coating includes a lubricant and an antimicrobial and/or pH buffering material. The device is configured such that, upon application of negative pressure to the catheter or stent, tissue of a urinary tract of a patient conforms or collapses onto the protective surface area and is thereby prevented or inhibited from occluding one or more protected drainage holes, ports or perforations of the catheter or stent.

The invention concerns coating composition comprising hydrophobic polymer for use as a photoreactive basecoat for a medical device or implant comprising a polymer made from monomers comprising: (a) 1 to 12 mol % of at least one photoactive monomer that is a hydrogen atom abstracter and (b) 99 to 88 mol % of one or more of acrylamides, methacrylamides, acrylates, methacrylates, and N-vinylpyrrolidone; wherein the polymer has a glass transition temperature (Tg) of less than 40° C.

A medical device includes: a substrate layer; an adhesive layer on at least a part of the substrate layer and containing a hydrophilic copolymer (1) containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO.sub.3H), a sulfuric acid group (—OSO.sub.3H), a sulfurous acid group (—OSO.sub.2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group; and a surface lubricious layer formed on at least a part of the adhesive layer and containing a hyaluronic acid or a salt thereof and a hydrophilic copolymer (2).

An ostomy appliance includes a multilayer composite film comprising at least one foam layer. An outer foam layer can function as a skin contact layer providing comfort and softness characteristics that are comparable to a nonwoven comfort layer. Preferably, at least one foam layer includes a vinyl-bond rich triblock copolymer and provides sound absorbing properties. The multilayer composite film can also include at least one layer comprising a filler to further enhance sound absorbing properties.

A liner is arranged for use in prosthetic and orthopedic devices. The liner defines first and second end portions, and inner and outer surfaces. The liner includes an inner layer having a frictional component and forms at least part of the periphery of the inner liner surface. The inner layer defines a plurality of apertures. A porous element is in communication with the inner liner surface and is connected to the inner layer such that the apertures permit a transfer of air from the inner surface to the porous element. A base layer adjoins the porous element and extends between the first and second end portions of the liner.

The disclosure provides a medical device that exhibits an excellent lubricating property. The medical device includes: a substrate layer; and a surface lubricious layer formed on at least a part of the substrate layer and containing a hyaluronic acid or a salt thereof and a hydrophilic copolymer containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO.sub.3H), a sulfuric acid group (—OSO.sub.3H), a sulfurous acid group (—OSO.sub.2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group.

A medical device includes: a substrate layer; an adhesive layer formed on at least a part of the substrate layer and containing a hydrophilic copolymer (1) containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO.sub.3H), a sulfuric acid group (—OSO.sub.3H), a sulfurous acid group (—OSO.sub.2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group; and a surface lubricious layer formed on at least a part of the adhesive layer and containing a polymer containing a structural unit derived from acrylamide and a hydrophilic copolymer (2).

Provided is a stent comprising: a stent skeleton; and a deposition layer containing a plurality of layers deposited on the stent skeleton; each layer of the deposition layer comprising crystalline cilostazol, at least one of the plurality of layers comprising a bioabsorbable polymer, wherein elution of not more than 5% by mass of the crystalline cilostazol occurs by 24 hours after the stent is brought into contact in vitro at 37° C. with an elution medium of a phosphate-buffered sodium chloride solution containing 0.25% by mass of sodium lauryl sulfate.

The present disclosure is related to inorganic, biocompatible material compositions for bioactivatable devices, devices, and products comprising transition metal chalcogenides, such as molybdenum sulfides, that can be converted in vivo from a non-bioactive state to a bioactive state upon exposure to physiological conditions, wherein the bioactivated transition metal chalcogenide derivatives, such as molybdenum sulfide derivatives, exhibit copper-chelating activities. Various methods for the application of these compositions for enhancing biocompatibility and reducing or modulating copper-dependent biological reactions are provided.

Methods for transferring graphene to substrates include at least a method for transferring a graphene-metal bilayer to a substrate to form a laminate thereof. The method can include applying a first continuous polymer layer to a graphene layer of the graphene-metal bilayer; applying a first discontinuous polymer layer to the first continuous polymer layer; applying a second continuous polymer layer to a metal layer of the graphene-metal bilayer; applying a second discontinuous polymer layer to the second continuous polymer layer; etching the first continuous polymer layer with a first etchant through the first discontinuous polymer layer; laminating the substrate by pressing the face of the graphene layer into a surface of the substrate; etching the second continuous polymer layer with a second etchant through the second discontinuous polymer layer, thereby transferring the graphene-metal bilayer to the substrate to form the laminate.