A medical implant includes a first implant body and a pre-coating covering at least a portion of an outer surface of the first implant body. The pre-coating has a negative Poisson's ratio. A method of making a medical implant includes applying a precursor material on a surface of a first implant body, the first implant body having a positive Poisson's ratio. A stimulus is applied to the precursor material, the stimulus causing the precursor material to form a coating having a negative Poisson's ratio

The present disclosure features adhesive compositions and methods of use thereof related to the medical, veterinary, and dental fields.

The present disclosure provides a bone-implantable device and methods of use. The bone-implantable device comprises a body having an exterior surface, wherein a portion of the exterior surface includes a cured osteostimulative material comprising MgO.

A hip implant system includes an artificial acetabular cup and an artificial acetabular liner. The liner includes or consists of a metal or an alloy, and is coated at least in sections with a ceramic coating.

In the present disclosure, an artificial joint stem includes a base including one or more grooves disposed on a surface of the base, and a coating film containing a calcium phosphate-based material and an antimicrobial material disposed on a part of the surface of the base. When among the one or more grooves, the groove located in a region where the coating film is disposed is defined as a first groove, and the groove located in a region where the surface of the base is exposed is defined as a second groove, a total length of the first groove is smaller than a total length of the second groove.

The invention provides a method for lubricating one or more surfaces, comprising applying gel-phase liposomes onto said one or more surfaces, wherein the temperature of said surface(s) at the time of lubrication is below the phase transition temperature T.sub.m of said liposomes. The method can be used for lubricating non-biological surfaces, and also for lubricating the surfaces of a biological tissue in a mammalian subject, e.g., for treating joint dysfunction.

The present disclosure provides a bone-implantable device and methods of use. The bone-implantable device comprises a body having an exterior surface, wherein a portion of the exterior surface includes a cured osteostimulative material comprising MgO.

The present invention relates to a medical implant for cartilage and/or bone repair at an articulating surface of a joint. The implant comprises a contoured implant body and at least one extending post. The implant body has an articulating surface configured to face the articulating part of the joint and a bone contact surface configured to face the bone structure of a joint, where the said articulating and bone contact surfaces face mutually opposite directions and said bone contact surface is provided with the extending post. A cartilage contact surface connects the articulating and the bone contact surfaces and is configured to contact the cartilage surrounding the implant body in a joint. The articulating surface has a layer that consists of titanium nitride (TiN) as the wear-resistant material. The cartilage contact surface has a coating that substantially consists of a material having chondrointegration properties.

Compositions and methods for the prevention and/or treatment of conditions involving disease or damage in mammalian cartilage and bone, using mesenchymal stem cells isolated with anti-integrin α10 antibodies are disclosed.

The present invention provides a new method related to regenerative medicine for the treatment of cartilage disorders, osteoarthritis and cartilage injury in particular. More particularly, it relates to an FGF-18 compound for use in tissue engineering and graft procedures, such as osteochondral or cartilage transplantation or autologous chondrocyte implantation (ACI).