The present disclosure relates to a control device or closed-loop control device, programmed to control or regulate a blood treatment apparatus during a treatment of a patient's blood carried out in a treatment session using an extracorporeal blood tubing set and the blood treatment apparatus while balancing liquid flows and conveying via different liquid pumps. The control device or closed-loop control device is further programmed to interrupt the balancing and/or the liquid flows at one or more predetermined interruption time points which lie within the duration of the treatment session.

A hemodiafiltration system with a disposable pumping unit is disclosed. An example system includes a medical fluid pump actuator, a medical fluid heater, a blood filter and a disposable unit. The example disposable unit includes a medical fluid cassette portion including a medical fluid cassette housing configured to be operatively connected to the medical fluid pump actuator to pump medical fluid through the medical fluid cassette portion when the medical fluid cassette portion is in fluid communication with a medical fluid source. The example medical fluid cassette portion is also configured to be placed in fluid communication with the blood filter and with an extracorporeal circuit communicating with the blood filter, the fluid communication enabling hemodiafiltration to be performed. The example disposable unit also includes a heater bag configured to be placed in operable communication with the medical fluid heater and in fluid communication with the medical fluid cassette portion.

A hemodiafiltration system with a disposable pumping unit is disclosed. An example system includes a medical fluid pump actuator, a medical fluid heater, a blood filter and a disposable unit. The example disposable unit includes a medical fluid cassette portion including a medical fluid cassette housing configured to be operatively connected to the medical fluid pump actuator to pump medical fluid through the medical fluid cassette portion when the medical fluid cassette portion is in fluid communication with a medical fluid source. The example medical fluid cassette portion is also configured to be placed in fluid communication with the blood filter and with an extracorporeal circuit communicating with the blood filter, the fluid communication enabling hemodiafiltration to be performed. The example disposable unit also includes a heater bag configured to be placed in operable communication with the medical fluid heater and in fluid communication with the medical fluid cassette portion.

The invention relates to a dialysis machine having a fluid system that has an inflow line for providing fresh dialyzing solution to a dialyzer and an outflow line for removing used dialyzing solution from the dialyzer, wherein the fluid system has a balancing system arranged between the inflow and outflow lines to balance the fluid volumes flowing through the lines, and wherein the fluid system has an ultrafiltration line that branches off from the outflow line between the dialyzer and the balancing system and has an ultrafiltration pump to be able to remove a defined volume of used dialyzing solution from the balance, and wherein an additional balancing chamber is provided that is arranged in a section of the inflow line disposed between the balancing system and the dialyzer or in a section of the outflow line disposed between the dialyzer and the branching of the ultrafiltration line.

A medical fluid line connector includes a body defining a central opening extending therethrough, a first projection extending from a first portion of the body, and a second projection extending from a second portion of the body, the second projection being circumferentially and axially offset from the first projection. The first portion of the body and second portion of the body are configured to separate from one another in response to a threshold amount of force being applied to the first projection and the second projection to rotate the first portion of the body and second portion of the body relative to one another.

Systems and methods are provided for performing a medical procedure within a patient's body that involves a thoracic duct including an ostium communicating with the patient's venous system. A distal end of a catheter is introduced through the patient's venous system into a body lumen adjacent the ostium of the thoracic duct. An expandable member on the distal end of the tubular member may be expanded adjacent the ostium, e.g., within the body lumen or the thoracic duct itself, and used to isolate the thoracic duct from the body lumen, whereupon a medical procedure may be performed via the thoracic duct. For example, lymphatic fluid may be removed from the thoracic duct through a lumen of the tubular member and/or one or more agents may be introduced into the thoracic duct through the tubular member.

In some examples, a smart assistant device may receive information associated with a previous medical treatment provided to a patient by one or more medical devices. The smart assistant device may determine, based at least in part on the received information and a medical treatment plan for the patient, an adjustment to one or more parameters of an upcoming scheduled medical treatment provided by the one or more medical devices. The smart assistant device may program or otherwise control the one or more medical devices to make the adjustment to the one or more parameters of the upcoming scheduled medical treatment provided by the one or more medical devices.

Embodiments of the technology described herein are based upon the discoveries that neutrophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries.

Embodiments of the technology described herein are based upon the discoveries that neutrophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries.

Hemofilters for in vivo filtration of blood are disclosed. The hemofilters disclosed herein provide an optimal flow of blood through the filtration channels while maintaining a pressure gradient across the filtration channel walls to enhance filtration and minimize turbulence and stagnation of blood in the hemofilter.