A thrombectomy system may include an elongate shaft that defines a high pressure lumen and a low pressure lumen. The high pressure lumen may terminate near an end of the low pressure lumen. An expandable capture basket may be disposed near the end of the low pressure lumen. A thrombectomy apparatus may include an elongate shaft, an evacuation lumen extending within the elongate shaft and a high pressure lumen extending within the elongate shaft. A capture apparatus may be disposed within a wire lumen that extends within the elongate shaft such that the capture apparatus extends distally from the wire lumen.

An insertable device is designed to control uterine hemorrhaging after birth by facilitating contractile movement of the uterus. An insertable device comprises a tube having a connecting portion and a suction portion and a seal positioned along the length of the connecting portion proximal to the suction portion. Upon insertion of the suction portion and seal into the uterus, the seal abuts a vaginal canal and forms a seal between a vaginal opening and the uterus. The suction portion comprises a first loop having an opening that is oriented away from an interior wall of the uterus when inserted into the uterus. The connecting portion of the tube couples to a pump that when actuated generates a negative pressure within the uterus, resulting in a uniform mechanical stimulus to the uterine wall in order to facilitate tamponade and contractile movement of the tissue.

A method for aspirating thrombus in a subject, the method including providing an aspiration catheter having a supply lumen, an aspiration lumen, and a first connector hydraulically coupled to the aspiration lumen. The method further includes providing a pressure sensor having an internal passageway and having a distal connector configured to hydraulically couple to the first connector, a proximal connector configured to couple to a vacuum source, and a valve disposed between the distal connector and the proximal connector, the valve having an open state and a closed state. Following inserting at least a distal portion of the aspiration catheter into the vasculature of a subject, changing the valve from one of the open state and closed state to the other of the open state and closed state such that a change in pressure may be detected by the control circuitry.

A system for aspirating thrombus that includes an aspiration catheter, a tubing set connected to the aspiration catheter, a pressurization element configured to couple to the tubing set and further configured to pressurize fluid from a first fluid source or allow pressurized fluid from the first fluid source to be transferred through a supply lumen of the aspiration catheter, and a sheath through which the aspiration catheter can be advanced.

A covered catheter, including a catheter body coated with a lubricant to facilitate entry into tissue of a user, and a covering sheath, including a sheath body to cover at least a portion of the catheter body in an extended position, and expose the catheter body in a retracted position, a first end cap disposed on at least a portion of a first end of the sheath body to enclose the first end of the sheath body, and a second end cap disposed on at least a portion of a second end of the sheath body to enclose the second end of the sheath body.

System and methods for stimulating cartilage formation at a first tissue site through a second tissue site is presented. The system includes a fluid source for supplying a therapeutic solution, a reduced pressure source for supplying reduced pressure, a fluid delivery manifold for deploying adjacent the first tissue site, and a vacuum manifold for deploying within the second tissue site. The fluid delivery manifold extends between a proximal end fluidly coupled to the fluid supply and a distal end having at least one aperture for delivering the therapeutic solution to the defect adjacent the articulating surface of the first tissue site. The vacuum manifold extends between a proximal end fluidly coupled to the reduced pressure source and a distal end having at least one aperture for delivering the reduced pressure to the first tissue site adjacent the opposing surface of the first tissue site.

Embodiments of negative pressure wound therapy systems and methods are disclosed. In one embodiment, an apparatus includes a housing, negative pressure source, circuit board, and one or more controllers. The circuit board can be supported by the housing and include a conductive pathway extending around at least part of a perimeter of a first side of the circuit board. The conductive pathway can be electrically coupled to an electrical ground for the circuit board. The one or more controllers can be mounted on the circuit board and activate and deactivate the negative pressure source.

A catheter for treatment of a defect internal of a human or animal body. The catheter may comprise a tube adapted for insertion into the body; an applicator disposed within and moveable relative to the tube; and a porous medium attached to the applicator; wherein the porous medium is capable of fitting inside the tube, whereby the applicator can be controlled at a proximal end of the tube to deploy the porous medium from a distal end of the tube so as to treat the defect.

A chest tube device with neurostimulation is provided, along with a method of electrically stimulating at least one of (i) one or more peripheral nerves and (ii) one or more nerve fibers of a thoracic region of a patient, to mitigate pain in patients undergoing chest tube implantation. The chest tube device includes a tubular member and an electro-analgesic region to provide neurostimulation to one or more peripheral nerves and/or nerve fibers of the thoracic region of the patient. The method includes electrically stimulating one or more peripheral nerves and/or nerve fibers of the thoracic region of the patient, and hyperpolarizing the one or more peripheral nerves and/or nerve fibers of the thoracic region to (i) reduce an amount of pain signals from being transmitted to the brain of the patient and/or (ii) prevent pain signals from being transmitted to the brain of the patient.

A method for capturing dislodged vegetative growth during a surgical procedure is provided. The method includes maneuvering, into a circulatory system, a first cannula having a distal end and an opposing proximal end, such that the first cannula is positioned to capture the vegetative growth en bloc. A second cannula is positioned in fluid communication with the first cannula, such that a distal end of the second cannula is situated in spaced relation to the distal end of the first cannula. A suction force is provided through the distal end of the first cannula so as to capture the vegetative growth. Fluid removed by the suction force is reinfused through the distal end of the second cannula. Subsequent to becoming dislodged, the vegetative growth is captured by the first cannula. A method for capturing a vegetative growth during removal of a pacemaker lead is also provided.