A method of externally sterilizing a drug delivery device utilizing Nitrogen Dioxide (NO2) is provided, including placing the drug delivery device in a sterilization chamber, introducing into the chamber a dose of NO2 having a concentration of between about 2 and 20 milligrams per Liter by applying a vacuum level of between about 10 and 600 Torr and holding the vacuum level for a dwell time of between about 2 and 20 minutes, repeating the step of introducing into the chamber a dose of NO2 for a number of pulses between about 1 and 24, purging the sterilization chamber of at least substantially all of the NO2, and aerating the sterilization chamber.

According to the invention, there is provided a medical apparatus including: one or more sterile pre-filled syringe; one or more first protective container including the one or more sterile prefilled syringe, wherein the one or more first protective container is impermeable to moisture and/or sterilizing agents; a second protective container including one or more medical components and the one or more first protective container; and a package impermeable to bacteria including the second protective container.

A male luer cap comprising a male luer, the male luer having a tapered sealing surface configured to mate with a female tapered surface of a female luer connector to form a substantially fluid-tight seal; a distal tip having a recess defined by a recess surface that is distal to the tapered sealing surface; and a water-soluble antimicrobial composition disposed on the recess surface; wherein the male luer is configured such that, when the male cap is mated with a female connector to form a substantially fluid-tight seal, a cavity is formed between the female tapered surface and the recess surface.

A syringe having an energy source disposed therein is disclosed. The syringe is capable of both the delivery and/or aspiration of materials as well as the delivery of an effective amount of various types of energy to a target to produce a desired result. A method utilizing the syringe to administer materials and to deliver energy to the material is also disclosed.

Syringe tip caps are described herein. Such syringe tip caps may include a cup, a cap, a locking feature, a peelable seal and an absorbent material. The cap having locking features and a chamber appropriately sized to adapt to and interlock with an annular wall of the cup.

A cleaning swab device and method for cleaning a fluid coupling or connector. The device includes a generally elongate cylindrical tubular swab body, and a channel formed at an end thereof to define at least one cleaning finger for insertion into a housing and/or port of the connector to remove residual fluids, clean and disinfect the connector. The cleaning device optionally further includes a guide stem or plunger configured to extend through the tubular body of the swab, having a plug at one end for sealing debris out of a lumen of the connector during cleaning.

To provide a container for a medical device, which enables easy removal of wrapping, thereby significantly reducing the labor for unpacking at the delivery destination such as a pharmaceutical company or a medical institution. Furthermore, the provided container for the medical device enables easy removal of wrapping even during an automated process in a filling machine for medical solutions, for example. In this container for a medical device, a holder holding at least one medical device is placed inside a container body having an opening at the top, and the opening is sealed with a gas-impermeable film. When sterilizing the exterior of the container using a sterilization gas, the sterilization gas does not permeate into the container due to the gas-impermeable film, so the medical device and the holder thereof placed inside the container are never exposed to the gas.

Disclosed herein are various embodiments of a multi-chamber syringe module for use in fine needle aspiration or other procedures. The multi-chamber syringe module includes a multi-chamber cartridge. The multi-chamber cartridge can include a plurality of fluid chambers. The multi-chamber syringe module also includes a needle manifold that is rotatably coupled to the multi-chamber cartridge. The multi-chamber syringe module further includes a luer fitting hub fixedly coupled to the needle manifold at a first end and selectively coupled to a biopsy needle at a second end.

A therapeutic substance delivery device is provided for delivering therapeutic substance to the subject. A sterile fluid path includes a needle at an upstream end of the sterile fluid path and an injection assembly at a downstream end of the sterile fluid path. The delivery device engages with a prefilled therapeutic substance reservoir, such that a disinfection chamber is defined between the sterile fluid path and the reservoir. The needle penetrates the disinfection chamber and subsequently the reservoir when the therapeutic substance delivery device and the reservoir are engaged with one another. A disinfection assembly is disposed within the delivery device and configured to disinfect the disinfection chamber prior to the needle penetrating the disinfection chamber. Control circuitry activates the disinfection assembly, terminates the activation of the disinfection assembly, and subsequently drives the needle to penetrate the disinfection chamber and subsequently the reservoir.

Apparatus and a method are presented, including disinfecting a disinfection chamber that is defined between (i) a prefilled therapeutic substance reservoir and (ii) a sterile fluid path disposed within a therapeutic substance delivery device. The sterile fluid path includes a needle at an upstream end of the sterile fluid path and an injection assembly at a downstream end of the sterile fluid path. The disinfection occurs subsequently to the prefilled therapeutic substance reservoir being engaged with the therapeutic substance delivery device. Subsequently to disinfecting the disinfection chamber, the disinfection chamber and then the reservoir are penetrated with the needle. Other applications are also described.