The invention relates to a medical high-pressure injector for injecting a liquid provided in a syringe (2.1, 2.2) into a patient, wherein the injector has at least one syringe holder (10) with an associated drive unit for the syringe (2.1, 2.2) held therein as well as connecting lines for transmitting the liquid from the syringe (2.1, 2.2) into a patient tube and/or for filling the syringe (2.1, 2.2) that is held in the syringe holder (10), wherein the connecting lines are embodied in an interchangeable control cassette (3) and the injector has a cassette holder (11) with a receiving chamber (110) that can be opened and closed, into which the control cassette (3) can be inserted.

A catheter devices/systems and methods therefrom are described herein for treating acute kidney in-jury, especially the contrast-induced acute kidney injury wherein the devices prevent the contrast dyes from entering into kidney and/or facilitate blood flow of kidney by said catheter system.

A method of maintaining an overall flow rate during a sequential delivery of at least two fluids to a patient's blood vessel includes delivering at least a first fluid into the patient's blood vessel at a first flow rate, delivering at least a second fluid into the patient's blood vessel at a second flow rate, and adjusting at least one of a first flow profile of the first flow rate and a second flow profile of the second flow rate to dampen a transient increase in the overall flow rate during a transition between delivering one of the first fluid and the second fluid to delivering the other of the first fluid and the second fluid.

The present disclosure provides a template for marking injection sites on a biological surface prior to performance of a medical procedure, wherein the template comprises a flexible sheet having marked positions or demarcated areas for each injection site, and wherein each marked position or demarcated area is associated with a unique identifier. Also provided are methods of using such disclosed templates in a medical procedure where an agent or material is injected into a patient.

A method of determining a local cerebrospinal fluid flow rate. The method including the steps of positioning a distal end of the catheter in a flow of cerebrospinal fluid of the patient, the catheter including an infusion port and at least one temperature sensor positioned at a fixed distance from the infusion port, infusing a bolus of a temperature controlled fluid through the infusion port into the flow of cerebrospinal fluid, and monitoring a temperature sensed by the at least one temperature sensor, wherein a change in the temperature sensed by the at least one temperature sensor over time is representative of a local cerebrospinal fluid flow rate in proximity to the infusion port.

A contrast liquid injector has a controller that calculates a necessary volume of the contrast medium based on a read out necessary dose of effective component per unit weight, weight of the subject, and concentration of the effective component. The injection rate of a base-operation condition is changed based on the calculated necessary volume of the contrast medium, wherein the predetermined injection time is unchanged, for all volumes of the contrast medium, when making the injection pattern, whereby a timing of an optimum concentration of the contrast medium will be substantially unchanged for all volumes of the contrast medium.

The present invention concerns a device for injecting a liquid product contained in a bag, the device comprising a housing consisting of two half-shells articulated about an axis of rotation in order to allow the relative movement of the half-shells relative to each other between: —an open position in order to put the bag in place and—a closed position for injecting the liquid product contained in the bag, remarkable in that: —one of the half-shells comprises a deformable bladder—called the “active bladder”—having a volume that varies under the action of a hydraulic ram supplying said bladder with hydraulic fluid, and—the other of the half-shells comprises a deformable damping cushion having a constant volume—called the “passive cushion”.

Drug delivery systems and methods are disclosed herein. In some embodiments, a drug delivery system can be configured to deliver a drug to a patient in coordination with a physiological parameter of the patient (e.g., the patient’s natural cerebrospinal fluid (CSF) pulsation or the patient’s heart or respiration rate). In some embodiments, a drug delivery system can be configured to use a combination of infusion and aspiration to control delivery of a drug to a patient. Catheters, controllers, and other components for use in the above systems are also disclosed, as are various methods of using such systems.

One embodiment provides a tightly targeted minimally invasive therapy (TTMIT) parathyroid tissue ablating instrument. A substance that cytotoxically ablates parathyroidal tissue during application in the parathyroidal tissue of therapeutically sufficient units of an electromagnetic energy having a frequency only ranging from ultraviolet to visible to near infrared. A substance delivery device is configured to introduce the substance into the parathyroidal tissue. An electromagnetic energy treatment device is configured to apply the therapeutically sufficient units of the electromagnetic energy within a thermal range that is non-cytotoxic to the parathyroidal tissue to the substance after the substance has been introduced by the substance delivery device. A sensor is configured to monitor activation of the substance as the therapeutically sufficient units of the electromagnetic energy are applied. The electromagnetic energy treatment device is further configured to modulate applying the therapeutically sufficient units of the electromagnetic energy once the substance has been activated.

A pressure jacket includes a barrel having a proximal end, a distal end, and a sidewall extending substantially circumferentially between the proximal end and the distal end along a longitudinal axis. The pressure jacket also includes at least one retaining member having at least one first lug protruding radially outward relative to an outer surface of the sidewall. The at least one first lug has at least one third surface tapered axially relative to the longitudinal axis of the barrel in a proximal direction. The at least one first lug is configured for engagement with a locking mechanism associated with a port on a fluid injector to releasably lock the pressure jacket with the fluid injector. At least a portion of the at least one third surface axially ejects the pressure jacket upon rotation of the pressure jacket about the longitudinal axis.