A61M5/007

Multiple fluid delivery system with multi-use disposable set and features thereof

A multi-use disposable set (MUDS) has at least one syringe having a proximal end and a distal end spaced apart from the proximal end along a longitudinal axis. The MUDS further has a plunger reciprocally movable within a syringe interior between the proximal end and the distal end. A manifold is in fluid communication with the distal end of the at least one syringe. At least one valve is in fluid communication with the syringe interior. The at least one valve is operable between a filling position for filling the syringe interior with fluid and a delivery position for delivering the fluid from the syringe interior. At least one connection port is in fluid communication with the manifold and the syringe interior when the at least one valve is in the delivery position. A multi-fluid delivery system having the medical connector and MUDS is also provided. Various features of the MUDS system are also described.

METHODS AND SYSTEMS FOR ESTABLISHING RETROGRADE CAROTID ARTERIAL BLOOD FLOW

Interventional procedures on the carotid arteries are performed through a transcervical access while retrograde blood flow is established from the internal carotid artery to a venous or external location. A system for use in accessing and treating a carotid artery includes an arterial access device, a shunt fluidly connected to the arterial access device, and a flow control assembly coupled to the shunt and adapted to regulate blood flow through the shunt between at least a first blood flow state and at least a second blood flow state. The flow control assembly includes one or more components that interact with the blood flow through the shunt.

PIEZOELECTRIC MEMBRANE PUMP FOR THE INFUSION OF LIQUIDS
20230097237 · 2023-03-30 ·

An infusion pump (10) includes a fluid chamber (28) having an outlet valve (34) and a piezo-stack actuator (36) comprising a stack of piezo-electric layers (38). An electronic processor (18) is programmed to operate the outlet valve and the piezo-stack actuator to pump fluid through the fluid chamber at a programmed flow rate.

RUBIDIUM ELUTION SYSTEM
20220347377 · 2022-11-03 ·

Provided are .sup.82Sr/.sup.82Rb elution systems that accept patient weight as a input function in order to determine an optimal quantity of radioactive rubidium-82 for delivery to a patient pursuant to an imaging scan. Also disclosed are systems that deliver a saline flush to remove residual .sup.82Rb from the system downstream of the generator, and preferably deliver the removed residual .sup.82Rb to the patient. Other disclosed systems measure the total volume of saline that flows through a .sup.82Sr/.sup.82Rb generator, a total volume of saline that flows through the generator and through a bypass line, or a total volume of saline received by a waste reservoir, in order to monitor system components so that optimal system functioning is assured.

AUTOMATED CORONARY ANGIOGRAPHY ANALYSIS
20220351369 · 2022-11-03 ·

A method and apparatus for analyzing diagnostic image data are provided in which a plurality of acquisition images of a vessel of interest having been acquired with a pre-defined acquisition method is received at a trained classifying device and classified, by the classifying device, to extract at least one quantitative feature of the vessel of interest from at least one acquisition image of the plurality of acquisition images. The at least one quantitative feature is then output associated with the at least one acquisition image while the acquisition of the diagnostic image data is still in progress and one or more adjustable image acquisition settings are adjusted based on the at least one quantitative feature to optimize the acquisition of the diagnostic image data.

RADIOPHARMACEUTICAL GENERATION AND INFUSION SYSTEMS
20230093338 · 2023-03-23 · ·

Provided herein are the safety features for radiopharmaceutical infusion system for treatment or diagnostic purpose, wherein infusion system comprises a controller, a source of radiopharmaceutical including other components. The controller is configured to perform automated quality control steps at the start of the system during daily quality control and ensure that system complies to desired technical attributes prior to administration to patients. The quality control steps comprise calibration, breakthrough testing, checking for unauthorized connection and/or malware in the system, network or other connected devices.

PHARMACEUTICAL PREPARATION WITH TRACING FUNCTION AND DELIVERY SYSTEM THEREFOR
20230089830 · 2023-03-23 · ·

Disclosed are a pharmaceutical preparation with a tracing function, and a delivery system therefor. The pharmaceutical preparation comprises a first drug and a second drug in a liquid or gaseous state, wherein the first drug and the second drug are each divided into multiple sections, which are arranged in series at intervals in a conduit. One of the first drug and the second drug is a tracer drug that can be developed in a medical imaging device in the human body. The first drug and the second drug are immiscible and satisfy compatibility requirements. The pharmaceutical preparation can comprise an aerobic contrast agent, an aerobic embolic agent and an aerobic perfusion agent. Same can be applied to a variety of contrast techniques by means of a one-step simple operation, saving the dosage of a drug while maintaining a high concentration of the drug.

Injector state logic with hemodynamic monitoring
11607489 · 2023-03-21 · ·

A fluid injection system including a graphical user interface, a fluid control module operatively connected to the graphical user interface, a monitoring control module provided in at least one of the graphical user interface and the fluid control module, a fluid injector operatively connected to the graphical user interface and the fluid control module, at least one fluid path set in fluid communication with the fluid control module, and a hemodynamic monitoring system operatively connected to the fluid path set and the monitoring control module. The hemodynamic monitoring system may be configured to receive electrical signals regarding pressure waves formed in medical fluid directed through the fluid path set based on a location of the fluid path set in a patient's vasculature, to convert the electrical signals to pressure wave form information, and to send the pressure wave form information to the monitoring control module.

EXPANDABLE DEVICE FOR TISSUE COLLECTION FROM AN AERODIGESTIVE BODY LUMEN
20230084261 · 2023-03-16 · ·

A device for obtaining tissue from the aerodigestive tract is provided. The device may have internal and external folds and a tissue collection surface for collecting a tissue sample from a body lumen, such as the nose or throat. The present invention is also directed to methods of collecting a tissue sample using the devices, described herein.

CALCULATING A FRACTIONAL FLOW RESERVE
20230084748 · 2023-03-16 ·

A method for vascular assessment is disclosed. The method, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to produce a stenotic model over the vasculature, the stenotic model having measurements of the vasculature at one or more locations along vessels of the vasculature. The method, in some embodiments, further comprises obtaining a flow characteristic of the stenotic model, and calculating an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.