The present invention relates to a device for measuring, recording, and acting in response to changes in air pressures encountered through the lumen of a connected needle. The device signals when it has been powered and signals when the device recognizes both pressures and pressure change rates indicative of synovial cavity joint penetration, such as knee joint penetration. Synovial cavity pressures detected and acted upon may either be supra- (positive) or sub-atmospheric (negative). Internal light emitting diodes and a laptop connected display are demonstrated as signaling and communication mechanisms. Methods for delivering medicaments into human and animal intra-articular cavities or joints such as synovial cavities are provided. Furthermore, methods for facilitating the diagnoses of joint effusion also are provided.

Systems and methods for automatic intravenous injection in accordance with embodiments of the invention are illustrated. One embodiment includes a method for automatically injecting a needle into a vein. The method includes steps for identifying an injection position using a first set of one or more sensors, positioning an injection mechanism at the identified injection position, and vertically inserting a needle until entry in a vein is detected using a second set of one or more sensors.

Provided are systems and methods for reducing pain during an injection or an insertion of an object into the skin of a subject.

A kit to facilitate creation of and compliance with a personalized injection site rotation plan includes a plurality of disposable injection devices adapted for giving an injection of a medication to a patient in need thereof, each disposable injection device having a permanent, distinctive mark that may be the same as or different from the distinctive mark on other disposable injection devices in the kit; and a plurality of user-defined association tools, wherein for each unique distinctive mark on a disposable injection device, at least one user-defined association tool has a distinctive mark that corresponds to the unique distinctive mark.

A hollow puncture needle includes: a needle body portion; a needle distal end portion that extends from the needle body portion in a distal direction and that includes a blade surface that is inclined with respect to an axis of the puncture needle; and an ultrasonic wave reflecting structure including at least one reflecting portion having a concave or hole shape that opens on an inner peripheral surface of the needle distal end portion. An inner surface of the reflecting portion includes a pair of inclined surfaces that face each other, wherein a distance between the inclined surfaces becomes smaller in a direction towards an outer peripheral surface side of the needle distal end portion. The inclined surfaces is parallel to the axis of the puncture needle.

An injector for delivering a therapeutic product may include a base having a flexible surface that conforms to various body contours of a patient and defines one or more an injection chambers. The injector may have a height that is substantially less than its width, thereby defining a low profile, which provides a larger more stable base that can pinch or stretch the skin in a controlled manner. The larger base can also accommodate larger volumes via multiple injection chambers and/or large combined primary containers.

A catheter assembly is provided that includes a puncture tool and a catheter. The puncture tool includes a hollow puncture needle configured to puncture a blood vessel, a detection portion that protrudes forward from a tip of the puncture needle and detects pulsation of the blood vessel, and a determination portion that determines whether the blood vessel is a vein or an artery based on the pulsation of the blood vessel detected by the detection portion. The detection portion includes a probe provided inside the hollow puncture needle that is configured to advance and retreat in an axial direction, and a sensor that detects pulsation of a blood vessel transmitted via the probe.

A puncture site patch includes: an elastomeric, self-sealing membrane with an exterior face and interior face; a spacer including an outer face and inner face, where the outer face of the spacer is coupled to the interior face of the membrane, and where the spacer further includes an aperture forming a cavity defined by the interior face of the membrane, spacer, and skin when applied to a user; an adhesive film that can adhere to skin, the adhesive film on the inner face of the spacer; at least one elongated tab that can move between a first position and a second position; where when in the first position the at least one elongated tab extends outward from a periphery of the spacer; and where when in the second position the puncture site patch is folded so that the aperture is sealed closed by the at least one elongated tab.

A needle assembly is disclosed, for use with an injection device. The needle assembly comprises a needle hub (20) having a needle (22) and a needle shield (40) arranged for relative axial movement with respect to the needle hub, between a retracted position in which the tip of the needle projects beyond a forward end of the shield and an extended position in which the tip of the needle does not project beyond the forward end of the shield. The needle shield (40) is axially biased towards the extended position. The needle shield (40) is further arranged to be torsionally biased for relative rotational movement with respect to the needle hub (20).

A method for gaining access to a vein includes implanting a vein localizer above or adjacent an anterior portion of a vein. The vein localizer features a fluorescent coating which emits visible light upon illumination by an external light. This makes visualization easier for a more confident vessel puncture at the first attempt. The invention is designed to reduce failed venipunctures, improve patient comfort and avoid unnecessary time and expense associated with multiple vein punctures.