Drug delivery member insertion depth sensing assemblies, drug delivery devices, and methods for determining an insertion depth of a drug delivery member are disclosed. The sensing assemblies can include electrical sensing assemblies with direct or indirect measurement components or optical sensing assemblies with one or more light sources and one or more photodiodes. A controller of the sensing assemblies can receive data associated with the drug delivery member in an insertion position. The data can then be correlated to an insertion depth of the drug delivery member.

A microneedle including a projection having a through hole formed in the projection in a direction that the projection extends, and a tubular member having an end surface configured to support the projection when the end surface is pressed against a skin and a fluid is supplied through the through hole of the projection to the skin. The projection has a length H along the direction that the projection extends and the supporting surface has an area S such that a ratio of S/H is in a range of from 2.1 to 10.5.

Methods of actuating a needle array device can include causing fluid to move through flow channels to needle apertures that are spaced apart from an inflow aperture at different distances where flow channels that have approximately equal pathway lengths and where the fluid can reach tips of the needle apertures approximately simultaneously, which can provide an approximately equal dosage or fluid volume through the tips of the needle apertures.

Methods of actuating a needle array device can include causing fluid to move through flow channels to needle apertures that are spaced apart from an inflow aperture at different distances where flow channels that have approximately equal pathway lengths and where the fluid can reach tips of the needle apertures approximately simultaneously, which can provide an approximately equal dosage or fluid volume through the tips of the needle apertures.

The disclosed system allows for the positioning of a sensor probe using a roto-linear mechanism. Specifically, the device allows for independent positioning of the probe along a linear axis and a rotary axis such that the linear axis includes a coupling that allows for arbitrary positioning of the linear axis with respect to the rotary axis. The probe can contain a plurality of sensors, such that the roto-linear mechanism can position the probe. In addition, the device allows for modular radial attachment points such that the probe can be radially positioned at arbitrary radii. The disclosed invention can be included in a system that includes software to manipulate and control the roto-linear motion of the device.

The disclosed system allows for the positioning of a sensor probe using a roto-linear mechanism. Specifically, the device allows for independent positioning of the probe along a linear axis and a rotary axis such that the linear axis includes a coupling that allows for arbitrary positioning of the linear axis with respect to the rotary axis. The probe can contain a plurality of sensors, such that the roto-linear mechanism can position the probe. In addition, the device allows for modular radial attachment points such that the probe can be radially positioned at arbitrary radii. The disclosed invention can be included in a system that includes software to manipulate and control the roto-linear motion of the device.

A cannula insertion system for inserting a cannula into a human or animal body, includes a cannula and a cannula insertion device to hold and insert the cannula into the human or animal body in an insertion direction. The cannula insertion system includes a safety device configured to retract the cannula or to release the cannula from the cannula insertion device when a force exerted on the cannula in a direction perpendicular to the insertion direction results in exceeding a respective safety threshold value.

A needle assembly includes: a needle comprising a hollow needle tube, a needle tip at a distal end of the hollow needle tube, and a cutting face disposed adjacent to the needle tip; and a needle hub that includes a tip and a base end, and holds the needle at the needle tip. The needle hub includes a needle tip side end face from which the needle tip projects. An outer diameter of the needle is within a range of 0.15 mm to 0.20 mm, inclusive. A projection needle length extending from the needle tip side end face to the needle tip is within a range of 0.50 mm to 1.25 mm, inclusive. A needle body length extending from the needle tip side end face to a proximal end of the cutting face in within a range of 0.10 mm to 0.70 mm, inclusive.

A needle assembly includes: a needle comprising a hollow needle tube, a needle tip at a distal end of the hollow needle tube, and a cutting face disposed adjacent to the needle tip; and a needle hub that includes a tip and a base end, and holds the needle at the needle tip. The needle hub includes a needle tip side end face from which the needle tip projects. An outer diameter of the needle is within a range of 0.15 mm to 0.20 mm, inclusive. A projection needle length extending from the needle tip side end face to the needle tip is within a range of 0.50 mm to 1.25 mm, inclusive. A needle body length extending from the needle tip side end face to a proximal end of the cutting face in within a range of 0.10 mm to 0.70 mm, inclusive.

A cannula insertion system for inserting a cannula into a human or animal body, includes a cannula and a cannula insertion device to hold and insert the cannula into the human or animal body in an insertion direction. The cannula insertion system includes a safety device configured to retract the cannula or to release the cannula from the cannula insertion device when a force exerted on the cannula in a direction perpendicular