To prevent accidental needle stick injuries, a syringe has a plunger configured to pull the syringe into the syringe barrel after clinical use. The syringe has an additional safety feature that restricts subsequent movement of the plunger. After the needle has been retracted in its entirety within the barrel of the syringe, movement of the plunger is restricted by a two-part locking mechanism, a notch on the plunger and a T-shaped slot on the barrel with a one-way catch section to prevent the needle tip from being pushed accidentally through the barrel wall.

The present invention provides a method for generating an immune response in a subject, comprising administering to the subject's skin an immunizing composition from a SARS-CoV-2 pathogen, wherein the composition is administered with a microneedle delivery device.

The present invention provides a method for generating an immune response in a subject, comprising administering to the subject's skin an immunizing composition from a SARS-CoV-2 pathogen, wherein the composition is administered with a microneedle delivery device.

Devices, systems, and methods are provided herein for delivering medication (e.g., insulin) via a wearable pump having a patch-style form factor for adhesion to a user’s body. The reusable pump may be coupled to a disposable cap housing a microdosing system for delivering precise, repeatable doses of medication to a cannula configured to deliver medication to a target infusion area beneath the user’s outer skin layer. The system further may include an applicator for inserting the cannula into the user’s skin and/or applying an adhesive pad to the skin.

A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.

A syringe, having a front portion carrying a hollow, axially extending needle, a container, running from said front portion and forming a container rear end portion, a plunger, extending and being movable axially in the container, the needle rear end being in fluid connection with the container and the plunger being arranged to suck liquid, e.g. a liquid comprising insulin, through the needle when drawn away from the needle and to discharge liquid through the needle when pushed towards the needle, the plunger having a piston portion, turned to the needle rear end, and a coupling portion arranged to co-act with the piston portion for moving the piston portion in the container.

The present disclosure relates to a method of pairing an electronic data logging device of a drug delivery device with an external electronic device and to a respective drug delivery device. The drug delivery device comprises a housing configured to accommodate the medicament and to receive and/or mechanically engage with the electronic data logging device. The drug delivery device further comprises a first device component and a second device component. The first device component is movable relative to the second device component from a first positional state to a second positional state. The first device component comprises a first outer surface, and the second device component comprises a second outer surface. At least one of the first outer surface and the second outer surface comprises a first code portion of a pairing code for establishing a communication link between the electronic data logging device and an external electronic device.

Disclosed is a safety syringe that comprises a needle sleeve (1), a needle base (3) and a core rod (2). First claws (34) on the needle base (3) are configured to clamp in a first groove (111) on an inner wall of the needle sleeve (1), one of a proximal end of the needle base (3) and a distal end of the core rod (2) is provided with second claws (33), and the other one thereof is provided with a position-limiting member; the second claws (33) are configured to abut against the position-limiting member along a slanted surface. When the core rod (2) slides towards a distal side to perform injection, the second claws (33) are forced to slide along the slanted surface to pass over the position-limiting member and become hooked onto the position-limiting member, thereby realizing interlocking of the needle base (3) and the core rod (2), and during this process, the core rod (2) slides to drive the first claws (34) to slip out of the first groove (111); or when the core rod (2) retracts, the core rod (2) exerts a pulling force on the needle base (2) towards the proximal side so as to force the first claws (34) to slip out of the first groove (111); the needle base (3) slides towards the proximal side together with the core rod (2), thereby simplifying the structure of the safety syringe.

A safety needle device may include: a hub configured to be connected to a vessel; a needle attached to the hub, the needle extending between a distal end, configured for insertion into a patient, and an opposed proximal end, configured for connection to the vessel; a shield slidable relative to the hub and rotationally constrained, wherein the shield is irreversibly slidable from an initial position, before injection, to a locking position, after injection, passing through an intermediate position; a housing attached to the hub and surrounding: a portion of the hub, a portion of the shield when the shield is in the initial position and in the locking position, and almost totally the shield when the shield is in the intermediate position; and an elastic member biased to push the shield toward the distal end and to resist a longitudinal sliding of the shield toward the proximal end.

A safety needle device may include: a hub configured to be connected to a vessel; a needle attached to the hub, the needle extending between a distal end, configured for insertion into a patient, and an opposed proximal end, configured for connection to the vessel; a shield slidable relative to the hub and rotationally constrained, wherein the shield is irreversibly slidable from an initial position, before injection, to a locking position, after injection, passing through an intermediate position; a housing attached to the hub and surrounding: a portion of the hub, a portion of the shield when the shield is in the initial position and in the locking position, and almost totally the shield when the shield is in the intermediate position; and an elastic member biased to push the shield toward the distal end and to resist a longitudinal sliding of the shield toward the proximal end.