Drug supply units are disclosed which comprise substrates having a plurality of holes formed therein.

The present disclosure relates to an encapsulated, pressurized, sublingual nano mist vapor delivery device, which may deliver a formula, including a micellized liquid nicotine formula. The device comprises a protective receptacle or housing, which preferably houses at least one canister, and a receptacle cap. The device may also comprise a custom actuator in communication with a metered valve for delivering a precise, known volume of at least one micellized liquid nicotine formula. Methods of manufacture and use are also disclosed herein.

A device and method for delivering a fluid as an ejected stream of droplets during inhalation uses inertial filtering to cause a first plurality of droplet particles generated by an ejector mechanism to pass through an airflow exit while a second plurality of droplet particles having a greater mass mean aerodynamic diameter than the first plurality of droplet particles fails to pass through the airflow exit.

A mesh nebulizer that atomizes and ejects liquid through a mesh portion includes a vibration portion including a vibration surface facing upward, a liquid supply portion that supplies liquid toward the vibration surface of the vibration portion, a sheet including the mesh portion, and a support frame that supports a peripheral edge of the sheet. The support frame includes a bottom plate that supports a lower surface of the peripheral edge of the sheet, the bottom plate having a flat annular shape, and a larger inner diameter than a diameter of the vibration surface, and a protrusion radially protruding inward from the bottom plate. The sheet including the mesh portion faces the vibration surface at an inclination angle and is in contact with a first portion of a peripheral edge of the vibration surface.

A vaporizing article, comprises a vaporizer drive circuit; one or more memories configured to store a percentage of at least one constituent in an inhalation media, one or more compensation values for at least one compensation category for the at least one constituent, and instructions; and a control circuit comprising a processor coupled with the one or more memories configured to run the instructions, the instructions configured to cause the processor to: receive a dose target for a constituent; determine whether to perform compensation for an inhalation media dose in order to ensure the dose target is met; when compensation is to be performed, determine the properly compensated inhalation media dose based on an associated compensation value for the constituent; and control the vaporizer drive circuit so as to dispense a compensated dose of the inhalation media.

Drug supply units are disclosed which comprise substrates having a plurality of holes formed therein.

Devices, and methods for generating variable inhalable products (e.g., variable density, phase, and size products) are provided. Methods for treating or preventing a disorder in a subject using variable products generated by the devices are also provided herein. Additionally, inhalers and breathing systems comprising the devices are provided.

The present disclosure relates generally to the field of nicotine delivery. The disclosure teaches a nicotine meta-salicylate. More specifically, the disclosure teaches a condensation nicotine aerosol where nicotine meta-salicylate is vaporized. This disclosure relates to aerosol nicotine delivery devices. The delivery devices can be activated by actuation mechanisms to vaporize thin films comprising a nicotine meta-salicylate. More particularly, this disclosure relates to thin films of nicotine salt with meta salicylic acid for the treatment of nicotine craving and for effecting smoking cessation.

Methods, systems, and devices are provided for generating a mist. In one embodiment, a fluid delivery device is provided that includes a housing, a fluid vaporizer disposed within the housing and configured to receive fluid and to produce an aerosol mist of liquid particles from the fluid, and a pump configured to accelerate the aerosol mist produced by the fluid vaporizer. Methods are provided for producing a mist, and the methods can include delivering a fluid to a fluid vaporizer that generates a first mist. The fluid vaporizer delivers the mist to a pump that generates a second mist from the first mist.

A device for vaporizing a composition. The device comprises a thermally conductive substrate having a surface, the surface comprising a thermally conductive surface structure. A dry composition capable of a solid to liquid phase change upon being heated to at least a select temperature is disposed on the surface structure. The surface structure is configured to form liquid droplets of the composition upon heating of the surface structure to at least the select temperature. The liquid droplets have a median diameter less than a median diameter of liquid droplets formed on a planar substrate surface heated to at least the select temperature.