In one embodiment, a method for manufacturing an aperture plate includes depositing a releasable seed layer above a substrate, applying a first patterned photolithography mask above the releasable seed layer, the first patterned photolithography mask having a negative pattern to a desired aperture pattern, electroplating a first material above the exposed portions of the releasable seed layer and defined by the first mask, applying a second photolithography mask above the first material, the second photolithography mask having a negative pattern to a first cavity, electroplating a second material above the exposed portions of the first material and defined by the second mask, removing both masks, and etching the releasable seed layer to release the first material and the second material. The first and second material form an aperture plate for use in aerosolizing a liquid. Other aperture plates and methods of producing aperture plates are described according to other embodiments.

An aerosol-generating device is provided, including: a piezoelectric transducer; drive circuitry connected to the piezoelectric transducer and configured to apply an oscillating current to the transducer; and control circuitry connected to the drive circuitry and configured to monitor a resonant behavior of the piezoelectric transducer, the control circuitry being further configured to control the operation of the drive circuitry based on the resonant behavior of the piezoelectric transducer, in which the piezoelectric transducer forms part of a transducer assembly in a liquid pump, and the transducer assembly includes a membrane or surface configured to contact a liquid aerosol-forming substrate, the transducer assembly being configured to drive the membrane or surface into vibration, the vibration of the membrane or surface forcing the liquid through an adjacent liquid valve in the liquid pump. A method of operating an aerosol generating device is also provided.

A suction device includes a heating unit that heats a base material and generates an aerosol; a communication unit that receives, through a communication link, information indicating a profile stipulating an operation of the heating unit; and a control unit that controls the operation of the heating unit in accordance with the information indicating the profile. The information indicating the profile includes a combination of information indicating time and information indicating a parameter pertaining to the operation of the heating unit at said time.

An aerosol-generating device includes: a housing having a liquid storage cavity for accommodating an aerosol-generating substrate; a metal element arranged outside the liquid storage cavity; a static electricity generating assembly including a positive terminal and a negative terminal, one of the positive terminal and the negative terminal being electrically connected to the metal element so as to cause a part of the aerosol-generating substrate that is close to the metal element in the liquid storage cavity to be charged by electrostatic induction when the static electricity generating assembly is electrified; and a vaporization sheet, that, when electrified, vaporizes the charged aerosol-generating substrate to generate a charged aerosol.

Systems and methods for providing respiratory therapy are disclosed. The system includes a nebulizer operable to aerosolize a medicament, a cylindrical mixing chamber, an impacting cap and a recirculation tube. The mixing chamber has an inlet port, an outlet port, an aerosol port in fluid communication with the nebulizer, and a drainage port. The inlet port receives a flow of breathing gas. The mixing chamber receives the aerosol via the aerosol port, entrains aerosol into the flow of breathing gas, and delivers the breathing gas entrained with aerosol to the outlet port. The impacting cap receives and coalesces a portion of the aerosol into droplets within the space defined by the mixing chamber and the impacting cap. The mixing chamber is also configured to direct rain-out resulting from the droplets to the drainage port. The system also includes a recirculation tube to return the rain-out to the nebulizer.

The present disclosure relates to drug administration. In an exemplary embodiment, a system can include a drug administration device configured to dispense a drug to a patient, a monitoring device configured to log a delivery event of drug delivery from the drug administration device into the patient, and a sensor configured to sense a patient parameter following delivery of the drug into the patient. In another exemplary embodiment, a drug administration device can include a drug holder configured to hold a drug, a dispensing mechanism configured to dispense the drug, and a sensor configured to sense a patient parameter, and the drug administration device can be configured to locally activate the drug at a target location in the patient. In another exemplary embodiment, methods, devices, and systems are provided to assess when operation of a drug dispensing mechanism is complete and to confirm whether drug administration was successful.

A nasal droplet delivery device and related methods for delivering precise and repeatable dosages to a subject via the nasal passageways and sinus cavities.

The invention relates to methods for generating an aerosol by nebulization of a composition comprising polyclonal immunoglobulin (Ig). The selection of an efficient membrane nebulizer and a composition optimized for nebulization with such membrane nebulizer results in a particularly efficient method of generating an aerosol for administration of Ig to the respiratory tract.

A substance delivery mask includes a body, an exhaling valve, an inhaled valve, and a fog module. The fog module comprises a controlling module, a container, and an atomizer. The controlling module is disposed on the body. The container is disposed on the controlling module, the container is storing a mixed liquid, and the mixed liquid includes water and a plurality of nanoparticles. The atomizer is disposed on the container, the atomizer is used to atomize the water of the mixed liquid to form fog particles, and the fog particles are wrapped several of the nanoparticles respectively. The substance delivery mask can encapsulate the water-soluble or water-insoluble medicines, or nutritional products in the fog particles generated from the atomizer. The present invention can deliver medicine, nutritional products or vaccines by inhalation or oral.

The present invention provides a system (10) for humidification of a pressurized flow of breathable gas delivered to a patient, the system comprising; a ventilator (12) for generating a pressurized flow of breathable gas; a patient circuit (14) in fluid communication with the ventilator and connectable to the respiratory system of a patient; and an aerosol generator (18). The patient circuit defines an internal space (26) for transporting the flow of breathable gas which internal space accommodates the outflow opening (20) of the aerosol generator. This enables to prevent so-called rainout and a relatively light weight portable system. The invention also relates to an insert (30) that is connectable to the patient circuit and that accommodates the aerosol generator.