A method for printing a three-dimensional part with an additive manufacturing system, which includes providing a part material that compositionally has one or more semi-crystalline polymers and one or more secondary materials that are configured to retard crystallization of the one or more semi-crystalline polymers, where the one or more secondary materials are substantially miscible with the one or more semi-crystalline polymers. The method also includes melting the part material in the additive manufacturing system, forming at least a portion of a layer of the three-dimensional part from the melted part material in a build environment, and maintaining the build environment at an annealing temperature that is between a glass transition temperature of the part material and a cold crystallization temperature of the part material.

Disclosed is a system and method for splitting dual lumens using hot stamping. The system includes a die assembly having a heated die with a septum that is configured to split the dual lumen to form a split catheter by splitting the septum of the dual lumen. The die can receive a pair of mandrels therethrough, wherein the mandrels are configured to support a dual lumen loaded thereon. The dual lumen and the mandrels are pushed via a block into the die until the dual lumen passes through the septum within the die and two lumens are fully formed. The lumens are cooled with an air blast and the mandrels are removed after the lumens are cooled.

A multi-layer composite structure, or heated build platform, to serve as a build foundation for printing 3D objects and providing non-destructive, auto-ejection of the printed object. The heated build platform is comprised of one or more layers including a low surface energy thermoplastic layer, a high flatness and dimensional stability layer, a heat spreading layer, a high thermal density layer, a heater layer, an active convection cooling device, a frame, and a bed leveling device. The layers of the heated build platform are implemented to provide steady state operating conditions for printing 3D objects.

A adaptive build environment to serve as a build foundation for printing 3D objects in an environment that is controlled and isolated both from outside conditions and within the print environment itself. The adaptive build environment is comprised of one or more modular panels including an active cooling subsystem having a first thermal heat sink component, a second thermal heat sink component, a convection generating device, an inner plate, an outer plate, and a gas or fluid exit. In some implementations, a segmented gas and fluid guidance system may be included in one or more of the panels of the adaptive build environment in place of, or in addition to, the second thermal heat sink. The panels of the adaptive build environment are implemented to provide steady state operating conditions for printing 3D objects.

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

A method for printing a three-dimensional part with an additive manufacturing system, which includes providing a part material that compositionally has one or more semi-crystalline polymers and one or more secondary materials that are configured to retard crystallization of the one or more semi-crystalline polymers, where the one or more secondary materials are substantially miscible with the one or more semi-crystalline polymers. The method also includes melting the part material in the additive manufacturing system, forming at least a portion of a layer of the three-dimensional part from the melted part material in a build environment, and maintaining the build environment at an annealing temperature that is between a glass transition temperature of the part material and a cold crystallization temperature of the part material.

The present invention relates to an external cooling system for a molten film tube produced by a blown film tubular extrusion process, comprised of a divergent cooling element with a divergent cooling interface containing a cooling gas deflector spaced adjacent to the molten film tube and providing an expelled cooling gas (i) in a path opposing the flow of the molten film tube toward a first exit gap and (ii) in a path with the flow of the molten film tube toward a second exit gap. A minimum gap between the divergent cooling interface and the molten film tube occurs at the first exit gap and/or the second exit gap. Advantageously, the divergent cooling interface is provided with one or more compound angles to maximize stability and cooling efficiency. Additionally, multiple cooling elements can preferably be arranged in a stackable configuration to achieve higher throughput rates. Operation is characterized by improved film holding forces without the presence of high noise levels or detrimental vibration, flutter, and drag. Additionally, employing simplified single air delivery channels, and a stackable design, significantly reduces complexity and manufacturing costs.

A post-molding cooling apparatus directs a stream of cooling fluid against a concave interior surface of a molded article to cool the molded article. The apparatus includes an outlet positioned to direct the stream of cooling fluid into an open end of the molded article. The interior surface of the molded article is concave. The outlet is configured to direct the stream of cooling fluid in a helical direction such that at least a portion of the concave interior surface of the molded article acts as a curved surface relative to a direction of flow of the stream of cooling fluid to create turbulent flow of the stream of cooling fluid against the concave interior surface of the molded article along a length of the concave interior surface from the open end of the molded article toward a closed end of the molded article.

A three-dimensional modeling apparatus for fabricating a three-dimensional object includes a plasticizing section that plasticizes a thermoplastic material to transform into a molten material; an ejection section for ejecting the molten material; a first air blowing section that blows air from a circumference of the nozzle toward the molten material ejected from the nozzle; a platform on which the molten material ejected from the nozzle is deposited; and a control unit that changes a relative positional relationship between the ejection section and the platform.