An ultrasonic medicine application device that strongly promotes medicine absorption, having a housing, a control panel and a circuit board inside the housing, a medicine supply mechanism and an ultrasonic massage mechanism on a bottom surface of the housing. The ultrasonic massage mechanism has a base panel having massage projections, and also an electrical ultrasonic vibration element, which drives the projections make high frequency ultrasonic vibration. The medicine supply mechanism is positioned between the ultrasonic massage mechanism and the circuit board, and is configured to supply medicine towards the ultrasonic massage mechanism.

A deliver device for a compound including: a housing, vial holding a compound; and a source of propellant, wherein the housing provides an inlet and an outlet for the vial, wherein the inlet is in fluid communication with the source of propellant and is directed against the compound and the outlet allows for delivery of the compound.

A deliver device for a compound including: a housing, vial holding a compound; and a source of propellant, wherein the housing provides an inlet and an outlet for the vial, wherein the inlet is in fluid communication with the source of propellant and is directed against the compound and the outlet allows for delivery of the compound.

A system for respiration-controlled application of aerosol in powder form during artificial respiration or assisted respiration of a patient including an interface contacting the patient's respiratory tract, a unit for generating a respiratory gas flow, at least one inspiration line through gas flow is conducted to the interface, an aerosol generator, at least one aerosol line through which the generated aerosol is conducted from the aerosol generator to the interface, and a respiration sensor that detects the patient's respiration signal. A valve in the at least one aerosol line is controlled based on the detected respiratory signal. An intermediate store for generated aerosol in powder form is arranged between the valve and the aerosol generator. The gas flow has a first pressure that is higher than or equal to ambient pressure and the aerosol has a second pressure that is higher than or equal to the first pressure.

A system for respiration-controlled application of aerosol in powder form during artificial respiration or assisted respiration of a patient including an interface contacting the patient's respiratory tract, a unit for generating a respiratory gas flow, at least one inspiration line through gas flow is conducted to the interface, an aerosol generator, at least one aerosol line through which the generated aerosol is conducted from the aerosol generator to the interface, and a respiration sensor that detects the patient's respiration signal. A valve in the at least one aerosol line is controlled based on the detected respiratory signal. An intermediate store for generated aerosol in powder form is arranged between the valve and the aerosol generator. The gas flow has a first pressure that is higher than or equal to ambient pressure and the aerosol has a second pressure that is higher than or equal to the first pressure.

A device for delivering a compound to the olfactory region of the nasal cavity includes an actuator body and a tip configured to removably couple to the actuator body. The actuator body comprises a propellant channel in fluid communication with a propellant canister. The tip comprises a tip stem, a dip tube, a delivery channel, one or more puncture members, and an outlet orifice. The tip stem receives a compound container containing the compound and the compound container moves between a sealed state and an unsealed state. The one or more puncture members are each configured to puncture the compound container when the compound container is in the unsealed state. Propellant released from the canister travels through the propellant channel and into the punctured compound container, thereby contacting the compound and propelling the compound through the delivery channel and out the outlet orifice.

A device for delivering a compound to the olfactory region of the nasal cavity includes an actuator body and a tip configured to removably couple to the actuator body. The actuator body comprises a propellant channel in fluid communication with a propellant canister. The tip comprises a tip stem, a dip tube, a delivery channel, one or more puncture members, and an outlet orifice. The tip stem receives a compound container containing the compound and the compound container moves between a sealed state and an unsealed state. The one or more puncture members are each configured to puncture the compound container when the compound container is in the unsealed state. Propellant released from the canister travels through the propellant channel and into the punctured compound container, thereby contacting the compound and propelling the compound through the delivery channel and out the outlet orifice.

Systems and methods are provided for delivering one or more drugs. In some embodiments, a drug delivery system includes a housing having a distal end with an inlet through which an inspiratory flow of air passes into the housing, a proximal end having a patient interface attached thereto, the patient interface being configured to interface with a user, and an inspiratory flow pathway extending from the distal end to the proximal end of the housing. A nitric oxide (NO) source is positioned within the housing and is configured to deliver NO-containing gas to the patient interface. A secondary drug source is positioned within the housing and is configured to deliver a secondary drug to the patient interface. A controller is configured to control an amount of NO-containing gas and an amount of the secondary drug delivered using a control scheme.

Provided is a system comprising at least one inhaler. Each of the at least one inhaler comprises a use determination system configured to determine at least one value of a usage parameter relating to use of the respective inhaler by a subject. The system further comprises a user interface and a processing module. The user interface is configured to enable user-inputting of an indication of a status of a respiratory disease being experienced by the subject. The processing module is configured to control the user interface to issue a prompt to input the indication based on the at least one value.

An apparatus for applying positive pressure nebulized liquid to a patient includes a funneled T-connector having a funnel with a first opening of a first diameter, a second opening of a second diameter smaller than the first diameter, and a funnel wall extending between the first and second openings. The funneled T-connector further has a cylindrical nebulizer port that extends outwardly from the funnel wall. A nebulizer cup assembly includes a nebulizer cup to contain liquid and a nebulizer cap to removably attach to a top region of the nebulizer cup. The nebulizer cap has a cylindrical nebulizer outlet sized to removably attach to the cylindrical nebulizer port. The cylindrical nebulizer outlet extends upwardly through the nebulizer passage, beyond the cylindrical nebulizer port, and into the internal funnel space such that a top edge of the cylindrical nebulizer outlet is located within the internal funnel space.