Provided is a curable composition which has chargeability into silicone molds and curability at excellent levels, less causes the silicone molds to swell, and allows the silicone molds to have better durability and a longer service life in repeated use. The curable composition according to the present invention contains curable compounds and a cationic initiator and is used for production of an optical component by molding using silicone molds. The curable compounds include (A) a cycloaliphatic epoxy compound in a content of 10 weight percent or more of the totality of all the curable compounds contained in the curable composition. Of the totality of all the curable compounds contained in the curable composition, 10 to 50 weight percent is a curable compound or compounds having a molecular weight of 400 or more.

Method for producing cosmetic products, preferably lipsticks, lip salves or lip glosses, the method including the steps of: providing a containment capsule or pod (7) containing an amount of preparation (1) for cosmetic product lower than 20 g; the pod extending along a central axis to a height H; introducing the pod or capsule (7) into a pouring chamber or seat (6) to at least of H; heating the pod or capsule (7) up to a predetermined temperature adapted to cause an at least partial phase change of the preparation (1) for cosmetic product; pouring the preparation (1) for cosmetic product into a sleeve (8) provided with an inner cavity (9) reproducing the negative shape of the poured cosmetic product to be obtained; cooling the cosmetic product poured in the sleeve (8); extracting the poured cosmetic product from the sleeve (8).

Method for producing cosmetic products, preferably lipsticks, lip salves or lip glosses, the method including the steps of: providing a containment capsule or pod (7) containing an amount of preparation (1) for cosmetic product lower than 20 g; the pod extending along a central axis to a height H; introducing the pod or capsule (7) into a pouring chamber or seat (6) to at least of H; heating the pod or capsule (7) up to a predetermined temperature adapted to cause an at least partial phase change of the preparation (1) for cosmetic product; pouring the preparation (1) for cosmetic product into a sleeve (8) provided with an inner cavity (9) reproducing the negative shape of the poured cosmetic product to be obtained; cooling the cosmetic product poured in the sleeve (8); extracting the poured cosmetic product from the sleeve (8).

Disclosed is a microneedle, the microneedle including a needle body portion formed using a water-soluble material; an active ingredient coating portion configured to coat the surface of the needle body portion, and including an active ingredient transferred to the biological tissue; and a waterproof coating portion configured to coat at least a portion of the surface of the active ingredient coating portion, and to protect the needle body portion and the active ingredient coating portion from moisture.

Disclosed is a microneedle, the microneedle including a needle body portion formed using a water-soluble material; an active ingredient coating portion configured to coat the surface of the needle body portion, and including an active ingredient transferred to the biological tissue; and a waterproof coating portion configured to coat at least a portion of the surface of the active ingredient coating portion, and to protect the needle body portion and the active ingredient coating portion from moisture.

Disclosed is a method of preparing a flexible deformable photonic crystal material for structural health monitoring, comprising the following steps: washing a grating master template; preparing and assembling a mold; obtaining an assembled mold by printing a three-dimensional mold comprising an upper die and a lower die by use of a 3D printing device and installing the grating master template on the three-dimensional mold; obtaining a polydimethylsiloxane (PDMS) one-dimensional photonic crystal film by replicating a one-dimensional grating structure of a surface of the grating master template by pouring PDMS into the assembled mold; finally, obtaining the PDMS one-dimensional photonic crystal film with a one-dimensional photonic crystal structure on a middle surface and protrusion structures at both ends by demolding, wherein the PDMS one-dimensional photonic crystal film is the flexible deformable photonic crystal material. A mechanochromic photonic crystal film is prepared by using a master template with a photonic crystal structure, a process is simple and easy to operate, a preparation period of a mechanochromic material is greatly shortened, and a preparation cost is reduced.

Disclosed is a method of preparing a flexible deformable photonic crystal material for structural health monitoring, comprising the following steps: washing a grating master template; preparing and assembling a mold; obtaining an assembled mold by printing a three-dimensional mold comprising an upper die and a lower die by use of a 3D printing device and installing the grating master template on the three-dimensional mold; obtaining a polydimethylsiloxane (PDMS) one-dimensional photonic crystal film by replicating a one-dimensional grating structure of a surface of the grating master template by pouring PDMS into the assembled mold; finally, obtaining the PDMS one-dimensional photonic crystal film with a one-dimensional photonic crystal structure on a middle surface and protrusion structures at both ends by demolding, wherein the PDMS one-dimensional photonic crystal film is the flexible deformable photonic crystal material. A mechanochromic photonic crystal film is prepared by using a master template with a photonic crystal structure, a process is simple and easy to operate, a preparation period of a mechanochromic material is greatly shortened, and a preparation cost is reduced.

A mold for producing a hydrogel support for a 3-dimensional (3D) cell culture, includes: an upper mold comprising a base and a plurality of upper unit molds protruding downward from the base to form accommodating portions of a female type corresponding to shapes of hydrogel supports, having through holes at bottoms thereof, and patterned at a lower portion of the base; a lower mold where a plurality of lower unit molds are patterned, the plurality of lower unit molds formed in a female type to respectively accommodate the plurality of upper unit molds protruding downward and having sealed lower portions; and an ejecting unit for separating, from the accommodating portions of the plurality of upper unit molds, the hydrogel supports that are coagulated after being inserted into the through holes respectively formed in the plurality of upper unit molds.

A mold for producing a hydrogel support for a 3-dimensional (3D) cell culture, includes: an upper mold comprising a base and a plurality of upper unit molds protruding downward from the base to form accommodating portions of a female type corresponding to shapes of hydrogel supports, having through holes at bottoms thereof, and patterned at a lower portion of the base; a lower mold where a plurality of lower unit molds are patterned, the plurality of lower unit molds formed in a female type to respectively accommodate the plurality of upper unit molds protruding downward and having sealed lower portions; and an ejecting unit for separating, from the accommodating portions of the plurality of upper unit molds, the hydrogel supports that are coagulated after being inserted into the through holes respectively formed in the plurality of upper unit molds.

A tubular structure fabricated by additive manufacturing from non-biological building material formulations, and featuring an elongated core, a shell encapsulating the core and an intermediate shell between the core and the shell. Each of the core, the shell and the intermediate shell is made of a different material or a different combination of materials. Both the core and the intermediate shell are sacrificial. Additive manufacturing of the tubular structure is usable for fabricating an object featuring properties of a blood vessel.