A flexible mat forming system may include an elongate, rotatable drum having a plurality of transverse rows of mold cavities about an outer periphery thereof, an elongate hopper positioned adjacent the drum, the hopper shaped to receive a hardenable paste and deposit the hardenable paste along a facing row of the plurality of transverse rows of mold cavities, a spool assembly for feeding a sheet of mesh material between the hopper and the facing row, and a retaining plate extending partially about the outer periphery of the drum and positioned on a downstream side of the elongate hopper, the retaining plate spaced sufficiently close to the outer periphery to retain the mesh material against the outer periphery of the drum and the hardenable paste within the mold cavities adjacent the retaining plate.

Multilayer riblet applique and methods of producing the same are described herein. One disclosed example method includes applying a first high elongation polymer material to a web tool, where the web tool is to be provided from a first roll, and heating, via a first heating process, the first high elongation polymer material. The disclosed example method also includes applying a second high elongation polymer material to the first high elongation polymer material, and heating, via a second heating process, the second high elongation polymer material. The disclosed example method also includes applying, via a laminating roller, a support layer to the second high elongation polymer material.

Multilayer riblet applique and methods of producing the same are described herein. One disclosed example method includes applying a first high elongation polymer material to a web tool, where the web tool is to be provided from a first roll, and heating, via a first heating process, the first high elongation polymer material. The disclosed example method also includes applying a second high elongation polymer material to the first high elongation polymer material, and heating, via a second heating process, the second high elongation polymer material. The disclosed example method also includes applying, via a laminating roller, a support layer to the second high elongation polymer material.

A method of preparing a membrane comprising the steps of: a) mixing together a membrane-forming polymer, a water-soluble polyetheramine, and a solvent, said mixture containing no component which will react chemically with the polyetheramine; and b) casting said mixture to form the polymer into a solid membrane.

A method of preparing a membrane comprising the steps of: a) mixing together a membrane-forming polymer, a water-soluble polyetheramine, and a solvent, said mixture containing no component which will react chemically with the polyetheramine; and b) casting said mixture to form the polymer into a solid membrane.

The present invention provides a microneedle patch of which continuous production is possible by a rotary method and in which a front end thereof is composed of hyaluronic acid, and a manufacturing method and a manufacturing device suitable for continuous production of the same.

The microneedle patch according to the present invention is one of which a myriad of needle-shaped parts composed of hyaluronic acid are pressed to be attached to a surface of an adhesive layer 4 laminated on a substrate 2, one of which part of the hyaluronic acid layer 8 which is coated on the surface of the adhesive layer 4 is formed into a needle-shaped part 6 so as to be pressed to be attached thereto, or one of which the hyaluronic acid layer 8 is laminated on the substrate 2 composed of a thin film and then pressed so as to be arranged into a myriad of needle-shaped parts 6. The microneedle patch is continuously manufactured by a method in which the adhesive layer 4 is coated on a substrate 2 by primary gravure coating followed by drying, and then an aqueous hyaluronic acid solution is coated by secondary gravure coating and pressed so as to form a needle-shaped part 6, or in which the hyaluronic acid layer 8 is coated on the substrate 2 and pressed so that part of the hyaluronic acid layer 8 is formed into a needle-shaped part 6. A manufacturing device which includes a first coating part 20 that coats the substrate 2 with an adhesive layer 4 or a hyaluronic acid layer 8, and a second coating part 30 including needle-forming rollers 33 and pressure rollers 35 that press the first drying part 26 and the substrate 2 so as to form a needle-shaped part 6, by a rotary method, is also included.

The present invention provides a microneedle patch of which continuous production is possible by a rotary method and in which a front end thereof is composed of hyaluronic acid, and a manufacturing method and a manufacturing device suitable for continuous production of the same.

The microneedle patch according to the present invention is one of which a myriad of needle-shaped parts composed of hyaluronic acid are pressed to be attached to a surface of an adhesive layer 4 laminated on a substrate 2, one of which part of the hyaluronic acid layer 8 which is coated on the surface of the adhesive layer 4 is formed into a needle-shaped part 6 so as to be pressed to be attached thereto, or one of which the hyaluronic acid layer 8 is laminated on the substrate 2 composed of a thin film and then pressed so as to be arranged into a myriad of needle-shaped parts 6. The microneedle patch is continuously manufactured by a method in which the adhesive layer 4 is coated on a substrate 2 by primary gravure coating followed by drying, and then an aqueous hyaluronic acid solution is coated by secondary gravure coating and pressed so as to form a needle-shaped part 6, or in which the hyaluronic acid layer 8 is coated on the substrate 2 and pressed so that part of the hyaluronic acid layer 8 is formed into a needle-shaped part 6. A manufacturing device which includes a first coating part 20 that coats the substrate 2 with an adhesive layer 4 or a hyaluronic acid layer 8, and a second coating part 30 including needle-forming rollers 33 and pressure rollers 35 that press the first drying part 26 and the substrate 2 so as to form a needle-shaped part 6, by a rotary method, is also included.

The present invention relates to a method for manufacturing an aerogel sheet. The method for manufacturing the aerogel sheet includes: a step (a) of preparing silica sol; a step (b) of preparing a gelling catalyst; a step (c) of injecting the silica sol, which is prepared in the step (a), to a surface of a blanket to impregnate the silica sol; a step (d) of injecting the gelling catalyst, which is prepared in step (b), to the surface of the blanket, into which the silica sol is impregnated, to gelate the silica sol; and a step (e) of cutting the blanket, in which the silica sol is gelated, to obtain a sheet in which the silica sol is gelated.

The present invention relates to a method for manufacturing an aerogel sheet. The method for manufacturing the aerogel sheet includes: a step (a) of preparing silica sol; a step (b) of preparing a gelling catalyst; a step (c) of injecting the silica sol, which is prepared in the step (a), to a surface of a blanket to impregnate the silica sol; a step (d) of injecting the gelling catalyst, which is prepared in step (b), to the surface of the blanket, into which the silica sol is impregnated, to gelate the silica sol; and a step (e) of cutting the blanket, in which the silica sol is gelated, to obtain a sheet in which the silica sol is gelated.

Multilayer riblet applique and methods of producing the same are described herein. One disclosed example method includes applying a first high elongation polymer material to a web tool, where the web tool is to be provided from a first roll, and heating, via a first heating process, the first high elongation polymer material. The disclosed example method also includes applying a second high elongation polymer material to the first high elongation polymer material, and heating, via a second heating process, the second high elongation polymer material. The disclosed example method also includes applying, via a laminating roller, a support layer to the second high elongation polymer material.