The present invention discloses an anti-hair loss and hair growth integrated core-shell microneedle patch, comprising a backing and a core-shell microneedle array attached to one side of the backing, the core-shell microneedle array comprises a plurality of microneedles arranged on the backing to form an array, each microneedle comprises a shell substrate material and an internal core, and the shell substrate material is loaded with nano-enzyme for removing excessive active oxygen. The present invention uses an anti-hair loss and hair growth integrated core-shell microneedle patch of the above mentioned structure, wherein the shell substrate material is rapidly degraded after the microneedle patch is applied to the skin, the nano-enzyme loaded by the shell substrate material can be passively released to remove active oxygen and promote angiogenesis in the microenvironment around hair follicles, the internal core of the microneedle is loaded with mesenchymal stem cell-derived exosomes, and the internal exosomes are released and conveyed to hair follicle niches after the shell substrate material is degraded, so that improvement of pigmentation and promotion of hair regrowth are possible.

Disclosed herein is a method of manufacturing heating elements for vehicle interior materials, which includes forming a base part having the same shape as a curved surface of a subject, forming an electrode part on an upper surface of the base part, and stacking a heating part on upper surfaces of the base part and electrode part. Accordingly, the heating element is manufactured in advance to have the same shape as the curved surface of the subject and then adhered to the subject so that the heating element is overlapped on and pressed against the subject without deformation. Thus, it is possible to make overall temperature distribution uniform and improve product quality.

A method and system reprocess soiled animal bedding material commingled with animal manure. In one aspect the soiled animal bedding material is separated in a shaker to send at least a preponderance of the manure to a holding tank. In another aspect the bedding is cleaned, rinsed and color is restored. The bedding material is subsequently dried and a bedding product, fertilizer product, and/or compacted product is formed. Alternatively, the bedding material is dried (without a compacting step) to form a product. In yet another aspect, the steps of separation, cleaning, rinsing and/or color restoration may be omitted.

An imprint lithography apparatus having a first frame to be mounted on a floor, a second frame mounted on the first frame via a kinematic coupling, an alignment sensor mounted on the second frame, to align an imprint lithography template arrangement with a target portion of a substrate, and a position sensor to measure a position of the imprint lithography template arrangement and/or a substrate stage relative to the second frame.

A method may comprise: laying up a first plurality of plies of material comprising thermoplastic resin and fiber to form an inner skin preform, the inner skin preform being a continuous sheet including alternating peaks and valleys; laying up a second plurality of plies of material comprising thermoplastic resin and fiber to form an outer skin preform; and joining the inner skin preform to the outer skin preform.

An elastic membrane having a physical property required for each portion of the elastic membrane and capable of uniformly polishing a workpiece is disclosed. The elastic membrane includes: a contact portion having a workpiece pressing surface for pressing a workpiece against a polishing surface; and a partition wall extending upward from the contact portion and forming a pressure chamber. The contact portion and at least a part of the partition wall are composed of a first rubber structure and a second rubber structure which are integrally formed, the first rubber structure has a first hardness, and the second rubber structure has a second hardness lower than the first hardness, the first rubber structure includes the workpiece pressing surface, and the second rubber structure includes the at least a part of the partition wall.

A shaping system comprises a dispensing station configured to dispense formable material on a substrate, a shaping station configured to contact the dispensed formable material on the substrate with a plate, a positioning system configured to move the substrate having the dispensed formable material from the dispensing system to the shaping station, and a cover having one or more walls. While the substrate having the dispensed formable material is moved by the positioning system from the dispensing station to the shaping station, the cover is positioned to enclose the substrate and the dispensed formable material such that a ratio of a diameter of the substrate to a distance between the cover and the substrate to 80:1 to 30:1.

An imprint apparatus that forms a pattern made of an imprint material on each of a plurality of shot regions of a substrate, includes a user interface configured to allow a user to perform editing for assigning each of the plurality of shot regions to any one of a plurality of groups such that each of the plurality of groups is formed by at least one shot region onto which the imprint material is continuously supplied from a dispenser.

Disclosed are methods for forming a double-sided optical sheet, and a vehicle lamp assembly having the double-sided optical sheet integrated therein. A first optical pattern is imprinted on a first side of a material, and a second optical pattern is imprinted on a second side of the material, opposite the first side. The first and second optical patterns are thereby formed on opposing sides of the same sheet. When oriented adjacent a light source, the double-sided optical sheet homogenizes light emitted from the light source. For a light source having a plurality of lighting elements, the double-sided optical sheet is configured to blend light emitted from the plurality of lighting elements to form one homogenous beam of light output resulting from a single light-modifying member.

A diffraction light guide plate comprising an optical layer having diffraction lattice pattern formed as an integrated structure without an interface on one surface thereof, where the optical layer having diffraction lattice pattern is a continuous phase of polymer comprising an episulfide compound, a thiol compound, and an aromatic cyclic compound having two or more hydroxyl groups, the diffraction light guide plate having excellent thickness uniformity and flatness as well as low haze and excellent visibility, and excellent mechanical properties such as pencil hardness and strength, and a method for manufacturing the diffraction light guide plate.