A method for treating patients with COVID-19 and/or other respiratory conditions includes administering eighty-five milligrams of dapsone twice daily for twenty-one days. A variety of dapsone formulations and delivery devices are disclosed, including an inhaler, nasal spray, nasal gel, otic formulation, intravenous formulation, oral solution, oral suspension, patch and suppository.

An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. The aerosolization apparatus further comprises a puncturing mechanism within the housing. The puncturing mechanism comprises an alignment guide and a puncture member, wherein the alignment guide comprises a surface adapted to contact the capsule while the puncture member is advanced into the capsule to create an opening in the capsule. At least a portion of the surface is sloped relative to the longitudinal axis of the capsule. Alternatively or additionally, the surface may comprise one or more protrusions. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule. The alignment guide allows for more consistent puncturing of the capsule and a longer lifetime of the apparatus.

A medicament delivery device is presented having a proximal disposable part arranged with a body and a delivery member cover telescopically arranged in relation to the body wherein the proximal disposable part is configured to receive a medicament container. A distal reusable power pack is detachably arranged with the proximal disposable part such that the delivery member cover has an extension position in which the delivery member cover is extended in the proximal direction to cover a medicament delivery member of the medicament container, and a retraction position in which the delivery member cover is retracted in the distal direction to expose said medicament delivery member. The distal reusable power pack can have a power unit, a rotational drive unit and a plunger unit, where the rotational drive unit is powered by the power unit and is configured to move the plunger unit upon being triggered.

A dispenser for powdery substances contained in a separate package that has a container part with removable container cover, wherein an aspirated air flow is further sucked predominantly through the container part after removal of the container cover from the container part, such that two air flows entering through slits in a lid that can be pivoted around a pivoting axis evacuate the container part from its two ends, and after merging enter a vortex chamber upstream from a mouthpiece. Outside air inlet openings for a third air flow are formed in a housing part covered by the lid in a radial extension to the pivoting axis.

An inhaler article includes a body extending along a longitudinal axis from a mouthpiece end to a distal end. A capsule cavity may be within the body bounded downstream by a mouthpiece. An air inlet at the distal end and an air outlet at the mouthpiece end. A first mouthpiece air channel may extend from the distal air inlet, through the capsule cavity to the mouthpiece air outlet. A second mouthpiece air channel may extend from a point downstream of the separator to the mouthpiece air outlet. The second mouthpiece air channel may be separate from the first mouthpiece air channel. A coating layer of flavour may be disposed on a surface of the second mouthpiece air channel and a protective layer may be disposed on the coating layer of flavour.

Device for dispensing a pulverulent product comprising a reservoir unit (100) connected on the one hand, to an air expulsion system (200) and on the other hand to a dispensing head (300) provided with a dispensing orifice (310), said reservoir unit (100) comprising a reservoir (110) having substantially the form of a hollow cylinder, with a distal opening (111), a proximal opening (112), and a metering passage (113) connecting said distal and proximal openings (111, 112), a one-way valve (115) being positioned between said metering passage (113) and said distal opening (111), said proximal opening (112) of said reservoir (110) forming a filling cone which tapers towards said metering passage (113) to facilitate filling of said metering passage (113) with a dose of powder.

The present invention relates to a device for delivering acetylsalicylic acid or a salt thereof for the administration thereof through oral inhalation route for the preventive or curative treatment of thrombohemolytic events, in particular for myocardial infarction.

Disclosed herein are diketopiperazine microparticles having a specific surface area of less than about 67 m.sup.2/g. The diketopiperazine microparticle can be fumaryl diketopiperazine and can comprise a drug such as insulin.

A dry-powder inhaler may include a first casing portion, a second casing portion, and a hinge arrangement connecting the first casing portion and the second casing portion. The dry-powder inhaler may be assembled by folding the first casing portion and the second casing portion together. The first casing portion may include a cavity for receiving a dose blister foil, said cavity being adapted to contain a dry-powder medicament. The first casing portion and the second casing portion when folded together may be adapted to form an inlet for allowing a lidding foil extending out there from and an outlet for providing the medicament.

A vaporizer device may include a pressure sensor and an ambient pressure sensor. The pressure sensor may be configured to measure a first pressure in an air flow path in the vaporizer device. The ambient pressure sensor may be configured to measure a second pressure corresponding to an atmospheric pressure. The vaporizer device may further include a controller. The controller may be configured to transition the vaporizer device to a first standby mode when the first pressure is equal to or greater than the second pressure for a first threshold quantity of time. While the vaporizer device is in the first standby mode, the controller may be further configured to transition the vaporizer device to a second standby mode when the second pressure is a threshold quantity greater than the first pressure and no motion event is detected for a second threshold quantity of time.