An arrangement for activating an aerosol dispenser having a conveying tube for conveying a liquid; a movable holding member holding the conveying tube; a rotatable base; and a container chamber between the holding member and the base, wherein the arrangement is configured to transmit a loading rotation of the base to a substantially axial loading movement of the holding member towards the base, and wherein the holding member has a locking structure exposed to the container chamber. An aerosol dispenser having the arrangement and a method for activating an aerosol dispenser are also provided.

A tensioning arrangement for an aerosol dispenser is presented where the tensioning arrangement has a conveying tube; an elastic member arranged to store mechanical energy from a substantially axial tensioning movement of the conveying tube; a rotatable member; a transmission mechanism configured to transmit a tensioning rotation of the rotatable member to the tensioning movement of the conveying tube, wherein the transmission mechanism has a cam profile and a cam follower arranged to follow the cam profile, wherein the cam profile has at least one priming structure; and wherein the tensioning arrangement is configured such that the conveying tube makes a temporary priming movement towards an initial position when the cam follower passes each priming structure during the tensioning movement of the conveying tube by means of the tensioning rotation of the rotatable member. An aerosol dispenser is also provided.

A vaporization apparatus includes an atomizer, a channel, and a cooler. The atomizer is provided to generate vapor from a vaporization substance by heating the vaporization substance, and the channel is in fluid communication with the atomizer, to enable fluid flow through the vaporization apparatus. The cooler is provided to cool the fluid.

There is provided in accordance with an exemplary embodiment of the invention, a device and a method for controlled extraction of at least one active substance from at least one type of plant matter by application of heat, the device comprising: a heating element adapted to apply heat to an area of the plant matter to extract the substance; and a mechanism adapted for moving the plant matter relative to the heating element. Optionally, the active substance is a restricted substance. There is also provided in accordance with an exemplary embodiment of the invention, a method of monitoring and controlling inhalation of a restricted substance. There is provided in accordance with an exemplary embodiment of the invention, a method of manufacturing a tape of plant matter comprising an active substance.

An inhaler includes a mouth-piece cover, a pressure sensor, a first indicator and a second indicator. The first indicator may be configured to indicate based on a state of the cover, and the second indicator may be configured to indicate based on an output of the pressure sensor. For example, when the mouthpiece cover opens, the first indicator may illuminate and a dose of medication may be transferred from a reservoir to a dosing cup. The second indicator may illuminate if an amount of inhaled medication reaches a predetermined threshold for successful inhalation.

A tidal dry powder inhaler comprising: a miniature pressure sensor, a sensor port of said sensor being pneumatically coupled to a flow channel through which a user can inhale; a processor configured to process data received from a sensing element of the sensor to make a determination that inhalation of a spontaneous breath through said flow channel is in progress; a controller configured to, responsive to said determination, issue a start dosing signal; and a dosing mechanism configured to release dry powder medicament into the flow channel during inhalation of said spontaneous breath in response to receiving said signal.

This invention relates to a fixed-dose dry powder inhalation formulation comprising fluticasone propionate and albuterol sulfate, together with an α-lactose monohydrate carrier. In the formulation, the albuterol sulfate stabilises fluticasone propionate.

A device and associated method for the dispensation of mists for therapeutic use, comprising: a dispensing member (2) for dispensing an air flow (3) within which micronized particles of a liquid or solid therapeutic substance are dispersed; a chamber (11) having at least one inlet (12) for said air flow (3) generated by the dispensing member (2) and at least one outlet (13) for said air flow (3) present inside the chamber (11) itself; and a communication conduit (10) interposed between said dispensing member (2) and said chamber (11) in order to introduce the air flow (3) into the chamber (11) itself; said chamber (11) being switchable between an operative condition of maximum volume in which it internally defines a space (20) for containing at least one user, and a non-operative condition of minimum volume suitable for transport and/or storage.

Some embodiments are directed to a compliance monitor for monitoring patient usage of a dry powder medicament delivery device, including a store of medicament housed within a main body portion, and a base portion which is rotatable with respect to the main body portion. The medicament delivery device also includes a medicament dispensing means for dispensing a dose of medicament into an inhalation chamber, a mouthpiece through which the dose of medicament may be inhaled by a user, and a replaceable cap. The compliance monitor includes a first portion for receiving and/or retaining the base portion of the medicament delivery device, and a second portion for releasably securing the medicament delivery device to the first portion. The arrangement and construction is such that the fitting of the second portion of the compliance monitor to the first portion of the compliance monitor does not include a screw fit.

A method for generating a flow profile of an inhalation device is described. The method comprises the step of measuring acoustic emissions induced by inhalation flow through the inhalation device. The method further comprises the step of detecting peak frequencies in the measured acoustic emissions and generating a flow profile based on the detected peak frequencies. A corresponding device is also described.